{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:57:39Z","timestamp":1791896259384,"version":"4.3.4"},"reference-count":84,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T00:00:00Z","timestamp":1721520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Mild cognitive impairment impacts a sizable segment of the older population, and often evolves into dementia within a few years. At this stage, subjects may benefit from non-pharmacological therapies that can delay or stop the progression of the mild cognitive impairment into dementia and are crucial for improvement in the subject\u2019s quality of life, while also being easily accessible and safe for use. Many research studies have shown that a variety of exercises, including cognitive training, have the potential to enhance or optimize cognitive function and general well-being. Recently, many authors have suggested video games as a promising approach for cognitive training and neurorehabilitation in older people, thanks to their increasing motivation and training effects through immersion in stimulating environments. Under this premise, our narrative review\u2019s objective is to discuss and summarize the body of existing material on the role of video games in improving cognitive performance, daily life activities, and depression symptoms in older individuals with different levels of cognitive decline. From the papers reviewed, it emerged that older subjects trained with video games showed a significant improvement in cognitive functions, sleep quality, and psychiatric symptoms, positioning video games as an intriguing and useful tool.<\/jats:p>","DOI":"10.3390\/brainsci14070731","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T07:57:23Z","timestamp":1721721443000},"page":"731","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Video Gaming in Older People: What Are the Implications for Cognitive Functions?"],"prefix":"10.3390","volume":"14","author":[{"given":"Liliana","family":"Dell\u2019Osso","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5437-7178","authenticated-orcid":false,"given":"Benedetta","family":"Nardi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Massoni","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Battaglini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"De Felice","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Bonelli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Pini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan Mirko","family":"Cremone","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Carpita","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1001\/archneur.56.3.303","article-title":"Mild cognitive impairment: Clinical characterization and outcome","volume":"56","author":"Petersen","year":"1999","journal-title":"Arch. Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorders, American Psychiatric Association. [5th ed.].","DOI":"10.1176\/appi.books.9780890425596"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.neubiorev.2017.10.026","article-title":"White matter microstructural abnormalities in amnestic mild cognitive impairment: A meta-analysis of whole-brain and ROI-based studies","volume":"83","author":"Yu","year":"2017","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3233\/JAD-2005-7307","article-title":"Mild cognitive impairment: Is it Alzheimer\u2019s disease or not?","volume":"7","author":"Petersen","year":"2005","journal-title":"J. Alzheimers Dis."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1056\/NEJMcp0910237","article-title":"Clinical practice. Mild cognitive impairment","volume":"364","author":"Petersen","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1212\/WNL.0000000000000055","article-title":"Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal","volume":"82","author":"Roberts","year":"2014","journal-title":"Neurology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1212\/WNL.0000000000004826","article-title":"Practice guideline update summary: Mild cognitive impairment: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology","volume":"90","author":"Petersen","year":"2018","journal-title":"Neurology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/neur.1995.0021","article-title":"Synapse loss and gliosis in the molecular layer of the cerebral cortex in Alzheimer\u2019s disease and in frontal lobe degeneration","volume":"4","author":"Brun","year":"1995","journal-title":"Neurodegeneration"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1212\/WNL.57.5.817","article-title":"Neuroanatomy of the self: Evidence from patients with frontotemporal dementia","volume":"57","author":"Miller","year":"2001","journal-title":"Neurology"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrneurol.2017.96","article-title":"A clinicopathological approach to the diagnosis of dementia","volume":"13","author":"Elahi","year":"2017","journal-title":"Nat. Rev. Neurol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000316119","article-title":"Nonpharmacological therapies in Alzheimer\u2019s disease: A systematic review of efficacy","volume":"30","author":"Olazaran","year":"2010","journal-title":"Dement. Geriatr. Cogn. Disord."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"S88","DOI":"10.1093\/geront\/gnx167","article-title":"Evidence-Based nonpharmacological practices to address behavioral and psychological symptoms of dementia","volume":"58","author":"Scales","year":"2018","journal-title":"Gerontologist"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/alz.12188","article-title":"Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations","volume":"17","author":"Sikkes","year":"2021","journal-title":"Alzheimers Dement."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1212\/CON.0000000000000313","article-title":"Mild cognitive impairment","volume":"22","author":"Petersen","year":"2016","journal-title":"CONTINUUM Lifelong Learn. Neurol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.jalz.2014.01.001","article-title":"A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer\u2019s disease","volume":"10","author":"Jessen","year":"2014","journal-title":"Alzheimers Dement."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.arr.2012.07.001","article-title":"Cognitive stimulation for dementia: A systematic review of the evidence of effectiveness from randomised controlled trials","volume":"12","author":"Aguirre","year":"2013","journal-title":"Ageing Res. Rev."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1123\/japa.2012-0272","article-title":"Physical and psychosocial function in residential aged-care elders: Effect of Nintendo Wii Sports games","volume":"22","author":"Keogh","year":"2014","journal-title":"J. Aging Phys. Act."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.18632\/aging.101970","article-title":"Comparison between physical and cognitive treatment in patients with MCI and Alzheimer\u2019s disease","volume":"11","author":"Fonte","year":"2019","journal-title":"Aging"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1186\/s12984-021-00917-0","article-title":"Comparison between the effects of exergame intervention and traditional physical training on improving balance and fall prevention in healthy older adults: A systematic review and meta-analysis","volume":"18","author":"Chen","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.23736\/S1973-9087.19.05899-4","article-title":"Using virtual reality-based training to improve cognitive function, instrumental activities of daily living and neural efficiency in older adults with mild cognitive impairment","volume":"56","author":"Liao","year":"2020","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"102146","DOI":"10.1016\/j.arr.2023.102146","article-title":"Virtual reality and cognitive rehabilitation for older adults with mild cognitive impairment: A systematic review","volume":"93","author":"Tortora","year":"2024","journal-title":"Ageing Res. Rev."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1097\/WCO.0000000000000791","article-title":"Serious video games and virtual reality for prevention and neurorehabilitation of cognitive decline because of aging and neurodegeneration","volume":"33","author":"Sokolov","year":"2020","journal-title":"Curr. Opin. Neurol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.amepre.2012.02.023","article-title":"Role of video games in improving health-related outcomes: A systematic review","volume":"42","author":"Primack","year":"2012","journal-title":"Am. J. Prev. Med."},{"key":"ref_24","first-page":"119","article-title":"Jogos Eletr\u00f4nicos como Instrumentos de Interven\u00e7\u00e3o no Decl\u00ednio Cognitivo\u2014Uma Revis\u00e3o Sistem\u00e1tica","volume":"9","author":"Cardoso","year":"2017","journal-title":"Rev. Psicol. IMED"},{"key":"ref_25","first-page":"6","article-title":"Um olhar para o uso de tecnologias no cuidado de idosos com defici\u00eancia cognitiva em tempos de pandemia","volume":"1","author":"Alves","year":"2020","journal-title":"Rev. Sci. Hist."},{"key":"ref_26","unstructured":"Entertainment Software Association (2010). Game Player Data, Entertainment Software Association. Available online: https:\/\/www.theesa.com\/data-insights\/."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1055\/s-0043-1764413","article-title":"Effects of cognitive interventions with video games on cognition in healthy elderly people: A systematic review","volume":"81","author":"Ishibashi","year":"2023","journal-title":"Arq. Neuropsiquiatr."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.appet.2017.05.009","article-title":"Gamified working memory training in overweight individuals reduces food intake but not body weight","volume":"124","author":"Dassen","year":"2018","journal-title":"Appetite"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Contreras-Somoza, L.M., Irazoki, E., and Toribio-Guzm\u00e1n, J.M. (2021). Usability and User Experience of Cognitive Intervention Technologies for Elderly People With MCI or Dementia: A Systematic Review. Front. Psychol., 12.","DOI":"10.3389\/fpsyg.2021.636116"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Michalski, S.C., Szpak, A., Saredakis, D., Ross, T.J., Billinghurst, M., and Loetscher, T. (2019). Getting your game on: Using virtual reality to improve real table tennis skills. PLoS ONE, 14.","DOI":"10.31234\/osf.io\/aw5gk"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/nn.3940","article-title":"Closed-loop training of attention with real-time brain imaging","volume":"18","author":"deBettencourt","year":"2015","journal-title":"Nat. Neurosci."},{"key":"ref_32","first-page":"55","article-title":"Interacting with the past, present, and future of exergames: At the beginning of a new life cycle of video games?","volume":"38","author":"Kooiman","year":"2015","journal-title":"Soc. Leis."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Stojan, R., and Voelcker-Rehage, C. (2019). A Systematic Review on the Cognitive Benefits and Neurophysiological Correlates of Exergaming in Healthy Older Adults. J. Clin. Med., 8.","DOI":"10.3390\/jcm8050734"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Carpita, B., Muti, D., Nardi, B., Benedetti, F., Cappelli., A., Cremone, I.M., Carmassi, C., and Dell\u2019Osso, L. (2021). Biochemical Correlates of Video Game Use: From Physiology to Pathology. A Narrative Review. Life, 11.","DOI":"10.3390\/life11080775"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Buitenweg, J.I., Murre, J.M., and Ridderinkhof, K.R. (2012). Brain training in progress: A review of trainability in healthy seniors. Front. Hum. Neurosci., 6.","DOI":"10.3389\/fnhum.2012.00183"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"van Muijden, J., Band, G.P., and Hommel, B. (2012). Online games training aging brains: Limited transfer to cognitive control functions. Front. Hum. Neurosci., 6.","DOI":"10.3389\/fnhum.2012.00221"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.bandc.2004.09.016","article-title":"Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning","volume":"56","author":"Ridderinkhof","year":"2004","journal-title":"Brain Cogn."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1080\/13825580600678442","article-title":"Differential course of executive control changes during normal aging. Neuropsychology, Development, and Cognition","volume":"14","author":"Treitz","year":"2007","journal-title":"Sect. B Aging Neuropsychol. Cogn.\/Aging Neuropsychol. Cogn."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1136\/jech.2010.111849","article-title":"Does retirement influence cognitive performance? the whitehall II study","volume":"65","author":"Roberts","year":"2011","journal-title":"J. Epidemiol. Community Health"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"735","DOI":"10.3758\/MC.36.4.735","article-title":"Rules and more rules: The effects of multiple tasks, extensive training, and aging on task-switching performance","volume":"36","author":"Buchler","year":"2008","journal-title":"Mem. Cognit."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1467-7687.2009.00846.x","article-title":"How useful is executive control training? Age differences in near and far transfer of task-switching training","volume":"12","author":"Karbach","year":"2009","journal-title":"Dev. Sci."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Buitenweg, J.I.V., van de Ven, R.M., Prinssen, S., Murre, J.M.J., and Ridderinkhof, K.R. (2017). Cognitive Flexibility Training: A Large-Scale Multimodal Adaptive Active-Control Intervention Study in Healthy Older Adults. Front. Hum. Neurosci., 11.","DOI":"10.3389\/fnhum.2017.00529"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"345","DOI":"10.2224\/sbp.1997.25.4.345","article-title":"Video games and the elderly","volume":"24","author":"Goldstein","year":"1997","journal-title":"Soc. Behav. Personal. Int. J."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1037\/a0013494","article-title":"Can training in a real-time strategy video game attenuate cognitive decline in older adults?","volume":"4","author":"Basak","year":"2008","journal-title":"Psychol. Aging"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/JGP.0b013e3181c534b5","article-title":"Exergames for subsyndromal depression in older adults: A pilot study of a novel intervention","volume":"18","author":"Rosenberg","year":"2010","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1682\/JRRD.2010.01.0011","article-title":"Stop of loss of cognitive performance during rehabilitation after total hip arthroplasty-prospective controlled study","volume":"47","author":"Brem","year":"2010","journal-title":"J. Rehabil. Res. Dev."},{"key":"ref_47","first-page":"29","article-title":"Neuropsychological testing through a Nintendo Wii console","volume":"154","author":"Gamberini","year":"2010","journal-title":"Stud. Health Technol. Inform."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1159\/000323950","article-title":"Computer-based, personalized cognitive training versus classical computer games: A randomized double-blind prospective trial of cognitive stimulation","volume":"36","author":"Peretz","year":"2011","journal-title":"Neuroepidemiology"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1037\/a0026268","article-title":"Effects of interactive physical-activity video-game training on physical and cognitive function in older adults","volume":"27","author":"Maillot","year":"2012","journal-title":"Psychol. Aging"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1089\/g4h.2017.0092","article-title":"Computer and Videogame Interventions for Older Adults\u2019 Cognitive and Everyday Functioning","volume":"8","author":"Belchior","year":"2019","journal-title":"Games Health J."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1089\/g4h.2020.0128","article-title":"Videogame and Computer Intervention Effects on Older Adults\u2019 Mental Rotation Performance","volume":"10","author":"Taylor","year":"2021","journal-title":"Games Health J."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Ramnath, U., Rauch, L., Lambert, E.V., and Kolbe-Alexander, T. (2021). Efficacy of interactive video gaming in older adults with memory complaints: A cluster-randomized exercise intervention. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0252016"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1089\/g4h.2017.0065","article-title":"Effects of Kinect Adventures Games Versus Conventional Physical Therapy on Postural Control in Elderly People: A Randomized Controlled Trial","volume":"7","author":"Bacha","year":"2018","journal-title":"Games Health J."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1007\/s00221-015-4196-x","article-title":"A 3-month intervention of Dance Dance Revolution improves interference control in elderly females: A preliminary investigation","volume":"233","author":"Chuang","year":"2015","journal-title":"Exp. Brain Res."},{"key":"ref_55","first-page":"203","article-title":"Active videogame-based physical activity vs. Aerobic exercise and cognitive performance in older adults: A randomized controlled trial","volume":"18","author":"Guimaraes","year":"2018","journal-title":"J. Phys. Educ. Sport"},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Manser, P., and de Bruin, E.D. (2021). Making the Best Out of IT: Design and Development of Exergames for Older Adults With Mild Neurocognitive Disorder\u2014A Methodological Paper. Front. Aging Neurosci., 13.","DOI":"10.3389\/fnagi.2021.734012"},{"key":"ref_57","unstructured":"Torres, A. (, January January). Cognitive effects of videogames on older people. Proceedings of the 7th ICDVRAT with ArtAbilitation, Maia, Portugal."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1017\/S1041610210001912","article-title":"Rehabilitation for dementia using enjoyable video-sports games","volume":"23","author":"Yamaguchi","year":"2011","journal-title":"Int. Psychogeriatr."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/gps.4075","article-title":"Interactive video gaming compared with health education in older adults with mild cognitive impairment: A feasibility study","volume":"29","author":"Hughes","year":"2014","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1089\/g4h.2018.0029","article-title":"Xbox 360 Kinect Cognitive Games Improve Slowness, Complexity of EEG, and Cognitive Functions in Subjects with Mild Cognitive Impairment: A Randomized Control Trial","volume":"8","author":"Amjad","year":"2019","journal-title":"Games Health J."},{"key":"ref_61","doi-asserted-by":"crossref","unstructured":"Jahouh, M., Gonz\u00e1lez-Bernal, J.J., Gonz\u00e1lez-Santos, J., Fern\u00e1ndez-L\u00e1zaro, D., Soto-C\u00e1mara, R., and Mielgo-Ayuso, J. (2021). Impact of an Intervention with Wii Video Games on the Autonomy of Activities of Daily Living and Psychological-Cognitive Components in the Institutionalized Elderly. Int. J. Environ. Res. Public Health, 18.","DOI":"10.3390\/ijerph18041570"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Lin, Y.F., Liu, M.F., Ho, M.H., Lin, Y.K., Hsiao, Y.L., Wang, M.H., Chang, C.C., and Montayre, J. (2022). A Pilot Study of Interactive-Video Games in People with Mild Cognitive Impairment. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19063536"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1007\/s40520-023-02374-2","article-title":"Effects of dance video game training on cognitive functions of community-dwelling older adults with mild cognitive impairment","volume":"35","author":"Sato","year":"2023","journal-title":"Aging Clin. Exp. Res."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"ii37","DOI":"10.1093\/ageing\/afl084","article-title":"Falls in older people: Epidemiology, risk factors and strategies for prevention","volume":"35","author":"Rubenstein","year":"2006","journal-title":"Age Ageing"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"191","DOI":"10.3109\/09593985.2015.1138009","article-title":"Comparison of the effects of virtual reality-based balance exercises and conventional exercises on balance and fall risk in older adults living in nursing homes in Turkey","volume":"32","author":"Tomruk","year":"2016","journal-title":"Physiother. Theory Pract."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.jsr.2011.02.002","article-title":"Reducing fall risk by improving balance control: Development, evaluation, and knowledge-translation of new approaches","volume":"42","author":"Maki","year":"2011","journal-title":"J. Saf. Res."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.maturitas.2013.02.009","article-title":"Risk factors for falls among older adults: A review of the literature","volume":"75","author":"Ambrose","year":"2013","journal-title":"Maturitas"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"S59","DOI":"10.1016\/S1353-8020(10)70205-4","article-title":"The effect of dance dance revolution gaming compared to conventional physical training on dual task walking costs in elderly","volume":"16","author":"Reith","year":"2010","journal-title":"Park. Relat. Disord."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3109\/07380577.2011.560627","article-title":"The effect of nintendo wii on balance: A pilot study supporting the use of the wii in occupational therapy for the well elderly","volume":"25","author":"William","year":"2011","journal-title":"Occup. Ther. Health Care"},{"key":"ref_70","doi-asserted-by":"crossref","unstructured":"Picchierri, G., Murer, K., and de Bruin, E.D. (2012). A cognitive-motor intervention using a dance video game to enhance foot placement accuracy and gait under dual task conditions in older adults: A randomized controlled trial. BMC Geriatr., 12.","DOI":"10.1186\/1471-2318-12-74"},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Schoene, D., Lord, S.R., Delbaere, K., Severino, C., Davies, T.A., and Smith, S.T. (2013). A randomized controlled pilot study of home-based step training in older people using videogame technology. PLoS ONE, 8.","DOI":"10.1371\/journal.pone.0057734"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1123\/JAPA.2013-0148","article-title":"Six weeks of unsupervised Nintendo Wii Fit gaming is effective at improving balance in independent older adults","volume":"23","author":"Nicholson","year":"2015","journal-title":"J. Aging Phys. Act."},{"key":"ref_73","first-page":"80","article-title":"Comparison of a traditional and a video game based balance training program","volume":"9","author":"Kliem","year":"2010","journal-title":"Int. J. Comput. Sci. Sport"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1097\/01.JGP.0000308881.22956.27","article-title":"Outcomes and predictors of late-life depression trajectories in older primary care patients","volume":"16","author":"Cui","year":"2008","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/JGP.0b013e3181b7f10e","article-title":"Subsyndromal depression and successful aging in older women","volume":"18","author":"Vahia","year":"2009","journal-title":"Am. J. Geriatr. Psychiatry"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1001\/archpsyc.60.7.664","article-title":"Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life","volume":"60","author":"Charney","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.neurobiolaging.2005.09.007","article-title":"Exercise training and depression in older adults","volume":"26","author":"Barbour","year":"2005","journal-title":"Neurobiol. Aging"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1089\/g4h.2019.0165","article-title":"Exergames and Depressive Symptoms in Older Adults: A Systematic Review","volume":"9","author":"Drazich","year":"2020","journal-title":"Games Health J."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1089\/g4h.2015.0100","article-title":"Exergames for Older Adults with Subthreshold Depression: Does Higher Playfulness Lead to Better Improvement in Depression?","volume":"5","author":"Li","year":"2016","journal-title":"Games Health J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1589\/jpts.29.2157","article-title":"The effect of a VR exercise program on falls and depression in the elderly with mild depression in the local community","volume":"29","author":"Yang","year":"2017","journal-title":"J. Phys. Ther. Sci."},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1089\/rej.2017.2041","article-title":"Effects of Dance Exergaming on Depressive Symptoms, Fear of Falling, and Musculoskeletal Function in Fallers and Nonfallers Community-Dwelling Older Women","volume":"21","author":"Rodrigues","year":"2018","journal-title":"Rejuvenation Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1080\/13607863.2020.1832442","article-title":"Impact of exergames on psychiatric symptoms in older adults with serious mental illness","volume":"25","author":"Heinbach","year":"2021","journal-title":"Aging Ment. Health"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jbmt.2021.07.029","article-title":"Effects of Xbox Kinect exercise training on sleep quality, anxiety and functional capacity in older adults","volume":"28","author":"Passos","year":"2021","journal-title":"J. Bodyw. Mov. Ther."},{"key":"ref_84","first-page":"264","article-title":"Development of a Videogame for the Promotion of Active Aging Through Depression Prevention, Healthy Lifestyle Habits, and Cognitive Stimulation for Middle-to-Older Aged Adults","volume":"10","author":"Otero","year":"2021","journal-title":"Games Health J."}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/14\/7\/731\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:20:43Z","timestamp":1760109643000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/14\/7\/731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,21]]},"references-count":84,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["brainsci14070731"],"URL":"https:\/\/doi.org\/10.3390\/brainsci14070731","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,21]]}}}