{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:45:09Z","timestamp":1791657909892,"version":"4.3.4"},"reference-count":69,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T00:00:00Z","timestamp":1729641600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University and University Hospital of Li\u00e8ge and its Algology Interdisciplinary Centre","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"University and University Hospital of Li\u00e8ge and its Algology Interdisciplinary Centre","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"University and University Hospital of Li\u00e8ge and its Algology Interdisciplinary Centre","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"Benoit Foundation","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"Benoit Foundation","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"Benoit Foundation","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"Fonds National pour la Recherche Scientifique (FNRS)","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"Fonds National pour la Recherche Scientifique (FNRS)","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"Fonds National pour la Recherche Scientifique (FNRS)","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"European Foundation of Biomedical Research (FERB)","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"European Foundation of Biomedical Research (FERB)","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"European Foundation of Biomedical Research (FERB)","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"National Natural Science Foundation of China","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"National Natural Science Foundation of China","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"National Natural Science Foundation of China","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"European Foundation of Biomedical Research (FERB) Onlus","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"European Foundation of Biomedical Research (FERB) Onlus","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"European Foundation of Biomedical Research (FERB) Onlus","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"Fund Generet of the King Baudouin Foundation","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"Fund Generet of the King Baudouin Foundation","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"Fund Generet of the King Baudouin Foundation","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]},{"name":"Mind Care International Foundation","award":["2017064"],"award-info":[{"award-number":["2017064"]}]},{"name":"Mind Care International Foundation","award":["C\/2020\/1357"],"award-info":[{"award-number":["C\/2020\/1357"]}]},{"name":"Mind Care International Foundation","award":["81920108023"],"award-info":[{"award-number":["81920108023"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background\/Objectives: Hypnosis shows great potential for managing patients suffering from fibromyalgia and chronic pain. Several studies have highlighted its efficacy in improving pain, quality of life, and reducing psychological distress. Despite its known feasibility and efficacy, the mechanisms of action remain poorly understood. Building on these insights, this innovative study aims to assess neural activity during hypnosis in fibromyalgia patients using high-density electroencephalography (EEG) and self-reported measures. Methods: Thirteen participants with fibromyalgia were included in this study. EEG recordings were done during resting state and hypnosis conditions. After both conditions, levels of pain, comfort, absorption, and dissociation were assessed using a numerical rating scale. Time perception was collected via an open-ended question. The study was prospectively registered in the ClinicalTrials.gov public registry (NCT04263324). Results: Neural oscillations showed increased theta power during hypnosis in the left parietal and occipital electrodes, increased beta power in the frontal and left temporal electrodes, and increased slow-gamma power in the frontal and left parietal electrodes. Functional connectivity using pairwise-phase consistency measures showed decreased connectivity in the frontal electrodes during hypnosis. Graph-based measures, the node strength, and the cluster coefficient were lower in frontal electrodes in the slow-gamma bands during hypnosis compared to resting state. Key findings indicate significant changes in neural oscillations and brain functional connectivity, suggesting potential electrophysiological markers of hypnosis in this patient population.<\/jats:p>","DOI":"10.3390\/brainsci14111047","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T04:28:43Z","timestamp":1729657723000},"page":"1047","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Exploring Electrophysiological Responses to Hypnosis in Patients with Fibromyalgia"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6378-6387","authenticated-orcid":false,"given":"Pradeep","family":"Kumar Govindaiah","sequence":"first","affiliation":[{"name":"Centre for Brain Research, Indian Institute of Science Campus, Bengaluru 560012, India"},{"name":"MILE Lab, Department of Electrical Engineering, Indian Institute of Science, Bengaluru 560012, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3386-2697","authenticated-orcid":false,"given":"A.","family":"Adarsh","sequence":"additional","affiliation":[{"name":"MILE Lab, Department of Electrical Engineering, Indian Institute of Science, Bengaluru 560012, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0960-4340","authenticated-orcid":false,"given":"Rajanikant","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of California San Francisco (UCSF), San Francisco, CA 94158, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9011-7496","authenticated-orcid":false,"given":"Olivia","family":"Gosseries","sequence":"additional","affiliation":[{"name":"Coma Science Group, GIGA Consciousness, Liege University, 4000 Liege, Belgium"},{"name":"Centre du Cerveau2, Liege University Hospital, 4000 Liege, Belgium"},{"name":"Conscious Care Lab, GIGA Consciousness, Liege University, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Malaise","sequence":"additional","affiliation":[{"name":"Interdisciplinary Algology Center, Liege University Hospital, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ir\u00e8ne","family":"Salamun","sequence":"additional","affiliation":[{"name":"Interdisciplinary Algology Center, Liege University Hospital, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luaba","family":"Tshibanda","sequence":"additional","affiliation":[{"name":"Department of Radiology, Liege University Hospital, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Laureys","sequence":"additional","affiliation":[{"name":"CERVO Brain Research Centre, Laval University, Qu\u00e9bec, QC G1V 0A6, Canada"},{"name":"Anesthesia, Critical Care and Pain Medicine Research, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA"},{"name":"Consciousness Science Institute, Hangzhou Normal University, Hangzhou 310030, China"},{"name":"Anesthesia and Perioperative Neuroscience Laboratory, GIGA Consciousness, Liege University, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6356-547X","authenticated-orcid":false,"given":"Vincent","family":"Bonhomme","sequence":"additional","affiliation":[{"name":"Interdisciplinary Algology Center, Liege University Hospital, 4000 Liege, Belgium"},{"name":"Anesthesia and Perioperative Neuroscience Laboratory, GIGA Consciousness, Liege University, 4000 Liege, Belgium"},{"name":"Department of Anesthesia and Intensive Care Medicine, Liege University Hospital, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Elisabeth","family":"Faymonville","sequence":"additional","affiliation":[{"name":"Conscious Care Lab, GIGA Consciousness, Liege University, 4000 Liege, Belgium"},{"name":"Oncology Integrated Arsen Bury Center, University Hospital of Liege, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4288-9237","authenticated-orcid":false,"given":"Audrey","family":"Vanhaudenhuyse","sequence":"additional","affiliation":[{"name":"Conscious Care Lab, GIGA Consciousness, Liege University, 4000 Liege, Belgium"},{"name":"Interdisciplinary Algology Center, Liege University Hospital, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2796-040X","authenticated-orcid":false,"given":"Aminata","family":"Bicego","sequence":"additional","affiliation":[{"name":"Conscious Care Lab, GIGA Consciousness, Liege University, 4000 Liege, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1176\/jnp.3.4.440","article-title":"Neurophysiological Correlates of Hypnosis and Dissociation","volume":"3","author":"Spiegel","year":"1991","journal-title":"J. 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