{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T20:10:05Z","timestamp":1787602205186,"version":"build-2736575974"},"reference-count":59,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Recovery and Resilience Plan (PNRR)","award":["1557"],"award-info":[{"award-number":["1557"]}]},{"name":"National Recovery and Resilience Plan (PNRR)","award":["CUP B53C22004090006"],"award-info":[{"award-number":["CUP B53C22004090006"]}]},{"name":"European Union\u2014NextGenerationEU","award":["1557"],"award-info":[{"award-number":["1557"]}]},{"name":"European Union\u2014NextGenerationEU","award":["CUP B53C22004090006"],"award-info":[{"award-number":["CUP B53C22004090006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background\/Objectives: The COVID-19 pandemic has led to increased mental health issues, particularly among long-COVID patients, who experience persistent symptoms post-recovery, potentially leading to chronic conditions. The psychological impact of long-COVID is still largely unknown, but it may contribute to mental disorders like Post-Traumatic Stress Disorder (PTSD). Given the global rise in anxiety and depression, exploring therapies like Eye Movement Desensitization and Reprocessing (EMDR) for long-COVID traumatic disorders is crucial. This study explores the effectiveness of remote EMDR therapy for PTSD-like symptoms in long-COVID conditions (LCC), assessing their emergence, the impact of LCC on mental health, and identifying key commonalities. It also examines the potential advantages of an artificial intelligence (AI)-powered platform for EMDR treatments for both therapists and patients, evaluating the response differences between remote and in-person treatment. Methods: We enrolled a total of 160 participants divided into two groups of 80, with the experimental group receiving EMDR treatment for PTSD-like symptoms via a remote AI-powered platform, and the control group receiving traditional in-person therapy. We compared the ANOVA for Subjective Units of Disturbance (SUDs) scores, PTSD Checklist for DSM-5 (PCL-5) scores, and Impact of Event Scale-Revised (IES-R) scores between our two groups for three cases: pre-treatment, post-treatment, and decrement. Results: Statistical significance analysis showed a consistent absence of significant differences between online AI-powered platforms and traditional in-presence sessions. This effectively confirms our hypothesis and highlights that no significant differences were observed between the two groups. Conclusions: The AI-supported remote platform demonstrates comparable efficacy in delivering EMDR therapy, confirming its potential as an effective alternative to traditional in-person methods while providing added advantages in accessibility and adaptability (e.g., remote areas, hikikomori, natural disasters).<\/jats:p>","DOI":"10.3390\/brainsci14121212","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T08:24:14Z","timestamp":1732868654000},"page":"1212","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Remote Eye Movement Desensitization and Reprocessing Treatment of Long-COVID- and Post-COVID-Related Traumatic Disorders: An Innovative Approach"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1846-9996","authenticated-orcid":false,"given":"Samuele","family":"Russo","sequence":"first","affiliation":[{"name":"Department of Psychology, Sapienza University of Rome, Via Dei Marsi 78, 00185 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0396-7019","authenticated-orcid":false,"given":"Francesca","family":"Fiani","sequence":"additional","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, 00185 Roma, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3336-5853","authenticated-orcid":false,"given":"Christian","family":"Napoli","sequence":"additional","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, 00185 Roma, Italy"},{"name":"Institute for Systems Analysis and Computer Science, National Research Council, Via dei Taurini 19, 00185 Roma, Italy"},{"name":"Department of Computational Intelligence, Czestochowa University of Technology, Ul. Gen. J. H. D\u0105browskiego 69, 42-201 Czestochowa, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"An overview of post\u2013covid-19 condition (long covid)","volume":"1","author":"Vu","year":"2021","journal-title":"Can. J. Health Technol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1146\/annurev-med-043021-030635","article-title":"Post-COVID-19 condition","volume":"74","author":"Nalbandian","year":"2023","journal-title":"Annu. Rev. 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