{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T07:26:03Z","timestamp":1785741963548,"version":"3.56.0"},"reference-count":72,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Introduction: Chronic alcohol use is a complex condition influenced by psychological, behavioral, and socio-demographic factors. This study aimed to develop a comprehensive psychosocial profile of individuals with alcohol use disorder (AUD) by examining associations between psychometric variables and relapse risk including repeated psychiatric hospitalizations. Methodology: A cross-sectional observational analytical study was conducted on a sample of 104 patients admitted for alcohol withdrawal management at the \u201cProf. Dr. Al. Obregia\u201d Psychiatric Clinical Hospital in Bucharest between March 2023 and September 2024. Participants completed a set of validated psychometric tools: the Drinker Inventory of Consequences\u2014Lifetime Version (DrInC), Readiness to Change Questionnaire\u2014Treatment Version (RTCQ), Drinking Expectancy Questionnaire (DEQ), and Drinking Refusal Self-Efficacy Questionnaire (DRSEQ). Additional data were collected on the socio-demographic (education level, socio-professional category), genetic (family history of alcohol use), and behavioral factors (length of abstinence, tobacco use, co-occurring substance use disorders). Results: Higher alcohol-related consequence scores (DrInC) were significantly associated with lower education (p &lt; 0.001, \u03b72 = 0.483), disadvantaged socio-professional status (p &lt; 0.001, \u03b72 = 0.514), and family history of alcohol use (p &lt; 0.001, \u03b72 = 0.226). Self-efficacy (DRSEQ) was significantly lower among individuals with co-occurring substance use (p &lt; 0.001) and nicotine dependence (p &lt; 0.001). Logistic regression showed that the DrInC scores significantly predicted readmission within three months (OR = 1.09, p = 0.001). Conclusions: Psychometric tools are effective in identifying individuals at high risk. Personalized, evidence-based interventions tailored to both psychological and socio-professional profiles, combined with structured post-discharge support, are essential for improving long-term recovery and reducing the readmission rates.<\/jats:p>","DOI":"10.3390\/brainsci15070741","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T13:44:19Z","timestamp":1752241459000},"page":"741","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Biopsychosocial Profile of Chronic Alcohol Users: Insights from a Cross-Sectional Study"],"prefix":"10.3390","volume":"15","author":[{"given":"Luciana Angela","family":"Ignat","sequence":"first","affiliation":[{"name":"Doctoral School, \u2018George Emil Palade\u2019 University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania"},{"name":"\u2018Prof. Dr. Alexandru Obregia\u2019 Clinical Psychiatric Hospital, 041914 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca Oana","family":"Tipa","sequence":"additional","affiliation":[{"name":"\u2018Prof. Dr. Alexandru Obregia\u2019 Clinical Psychiatric Hospital, 041914 Bucharest, Romania"},{"name":"Department of Psychiatry, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Roxana","family":"Cehan","sequence":"additional","affiliation":[{"name":"Plastic and Reconstructive Surgery, Emergency Clinical County Hospital of Targu Mures, 540136 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8567-8459","authenticated-orcid":false,"given":"Vladimir Constantin","family":"Bac\u00e2rea","sequence":"additional","affiliation":[{"name":"Department of Scientific Research Methodology, \u2018George Emil Palade\u2019 University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"ref_1","unstructured":"Alcohol n.d.. 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