{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:42:36Z","timestamp":1760060556839,"version":"build-2065373602"},"reference-count":46,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background: Unruptured cerebral aneurysms pose a significant neurosurgical challenge due to their potential for rupture, which can lead to devastating subarachnoid hemorrhage. Advances in imaging have increased incidental detection of multiple unruptured aneurysms, necessitating tailored management strategies to balance rupture risk against treatment complications. Methods: We retrospectively analyzed 41 patients with 101 unruptured cerebral aneurysms, assessing demographics, aneurysm size and location, treatment modalities, and clinical outcomes. Descriptive statistics and correlation analyses examined associations between aneurysm characteristics, comorbidities, and post-treatment complications. Results: Most aneurysms were small (&lt;10 mm, 48.5%), primarily located at the Middle Cerebral Artery Bifurcation (27.7%). Hypertension (56.1%) and smoking (53.7%) were prevalent risk factors. Clipping was the most common intervention (81.2%), with 41.4% of patients experiencing post-operative complications and 36.6% developing neurological deficits. Conclusions: This study underscores the difficulties in managing multiple unruptured cerebral aneurysms owing to diverse aneurysm characteristics and patient risk factors such as hypertension, hyperlipidaemia, and smoking. Clipping was the predominant intervention, with time customized for each individual case. Despite the occurrence of problems such as vasospasm and neurological difficulties, the majority of patients maintained functional independence. The results provide significant insights into the clinical attributes, therapeutic strategies, and outcomes for this patient cohort.<\/jats:p>","DOI":"10.3390\/brainsci15090973","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T12:27:41Z","timestamp":1757507261000},"page":"973","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Management and Outcomes of Multiple Unruptured Cerebral Aneurysms: A Descriptive Cohort Analysis"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3131-4104","authenticated-orcid":false,"given":"Oday","family":"Atallah","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Evangelic Hospital Oldenburg, Carl von Ossietzky University Oldenburg, 26129 Oldenburg, Germany"},{"name":"Medical School Hannover, 30625 Hannover, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khadeja","family":"Alrefaie","sequence":"additional","affiliation":[{"name":"Kuwait Institute for Medical Specialization, Kuwait 15503, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1168-8536","authenticated-orcid":false,"given":"Amr","family":"Badary","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical University Lausitz, 03048 Cottbus, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1212\/CON.0000000000000835","article-title":"Management of Unruptured Cerebral Aneurysms and Arteriovenous Malformations","volume":"26","author":"Ruigrok","year":"2020","journal-title":"Continuum"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1136\/practneurol-2020-002521","article-title":"Management of incidental unruptured intracranial aneurysms","volume":"20","author":"Renowden","year":"2020","journal-title":"Pract. 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