{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T05:14:45Z","timestamp":1783401285926,"version":"3.54.6"},"reference-count":69,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Extracranial\u2013intracranial (EC-IC) bypass surgery remains an essential tool in the management of complex cerebrovascular disease, including chronic-ischemic hypoperfused territory as well as intracranial aneurysms requiring parent vessel sacrifice. Reliable postoperative surveillance of graft patency and hemodynamic function is central to long-term success. Sonographic imaging has evolved over four decades from indirect extracranial Doppler waveform analysis through intraoperative microvascular Doppler, quantitative duplex ultrasonography, and transcranial Doppler assessment of intracranial hemodynamics to the contemporary development of trans-sonolucent cranioplasty ultrasonography (TCUS). TCUS, enabled by the replacement of the autologous bone flap with an acoustically transparent polymethyl methacrylate (PMMA) cranioplasty, permits direct, real-time visualization of the anastomosis and surrounding intracranial vasculature. This can be performed at the bedside and in the outpatient setting, without radiation or contrast. Current evidence, drawn largely from small series and early multicenter experience, positions TCUS as a reliable and potentially cost-effective complement to digital subtraction angiography for serial bypass surveillance, though prospective validation remains needed. This review traces the full arc of sonographic bypass monitoring and addresses current evidence, technical considerations, established quantitative parameters, and directions for future investigation.<\/jats:p>","DOI":"10.3390\/brainsci16070672","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:11:57Z","timestamp":1782785517000},"page":"672","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sonographic Extracranial\u2013Intracranial Bypass Monitoring: Technical Evolution and Current Evidence"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0369-9704","authenticated-orcid":false,"given":"Eric A.","family":"Grin","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY 10016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erez","family":"Nossek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, NYU Grossman School of Medicine, New York, NY 10016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s10143-018-0966-9","article-title":"Bypass in neurosurgery-indications and techniques","volume":"42","author":"Wessels","year":"2019","journal-title":"Neurosurg. 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