{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:06:11Z","timestamp":1784192771599,"version":"3.55.0"},"reference-count":139,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015550","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["RRC-2026-23688274"],"award-info":[{"award-number":["RRC-2026-23688274"]}],"id":[{"id":"10.13039\/501100015550","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>Background\/Objectives: Spinal cord injury (SCI) causes heterogeneous motor, sensory, autonomic, and participation limitations; recovery priorities vary by injury level, completeness, time since injury and residual function. Robotic rehabilitation has expanded from assistive technology to restorative, compensatory and health-promoting interventions, but patient-tailored prescription frameworks remain underdeveloped. Methods: PubMed\/MEDLINE was searched from database inception to May 2026 using predefined domain-specific strategies, and findings were synthesized narratively to integrate mechanistic, clinical, safety and implementation evidence. Results: Robotic systems can increase task-specific repetition, sensorimotor feedback, active engagement and quantitative monitoring. Upper-limb robotics are feasible in cervical SCI and may support reach, grasp and activities of daily living, although SCI-specific controlled evidence remains limited. Lower-limb exoskeletons and locomotor robots can support gait practice, upright mobility, exercise exposure and selected secondary health outcomes, but walking speed, energy expenditure, cost, supervision needs and community translation remain important barriers. Sensory and non-motor effects, including proprioceptive input, spasticity, pain, bowel routine, cardiometabolic conditioning, participation and psychological well-being, are clinically relevant but should be interpreted according to evidence strength. Robotics combined with functional electrical stimulation, virtual reality, brain\u2013computer interfaces, non-invasive brain stimulation and artificial intelligence-driven adaptation is promising but not yet routine. Conclusions: Robotic rehabilitation in SCI should be prescribed through a severity-based process that considers lesion level, American Spinal Injury Association Impairment Scale grade, residual voluntary and sensory function, safety, patient priorities and measurable goals. The proposed framework supports transparent selection and prospective validation of individualized robotic rehabilitation and shifts decisions beyond device availability toward clinically meaningful and equitable implementation.<\/jats:p>","DOI":"10.3390\/brainsci16070732","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T09:51:09Z","timestamp":1783936269000},"page":"732","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Robotic Rehabilitation in Spinal Cord Injury: Neurophysiological Basis and Severity-Based Clinical Framework"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8566-3166","authenticated-orcid":false,"given":"Rocco Salvatore","family":"Calabr\u00f2","sequence":"first","affiliation":[{"name":"Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) Centro Neurolesi Bonino Pulejo, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5012-4425","authenticated-orcid":false,"given":"Andrea","family":"Calderone","sequence":"additional","affiliation":[{"name":"Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) Centro Neurolesi Bonino Pulejo, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana Di","family":"Gregorio","sequence":"additional","affiliation":[{"name":"Unipolar Spinal Unit, Cannizzaro Hospital for Emergency Care, 95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Pia","family":"Onesta","sequence":"additional","affiliation":[{"name":"Unipolar Spinal Unit, Cannizzaro Hospital for Emergency Care, 95126 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Quartarone","sequence":"additional","affiliation":[{"name":"Scientific Institute for Research, Hospitalization and Healthcare (IRCCS) Centro Neurolesi Bonino Pulejo, 98124 Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Lu, Y., Shang, Z., Zhang, W., Pang, M., Hu, X., Dai, Y., Shen, R., Wu, Y., Liu, C., and Luo, T. (2024). Global incidence and characteristics of spinal cord injury since 2000\u20132021: A systematic review and meta-analysis. BMC Med., 22.","DOI":"10.1186\/s12916-024-03514-9"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Liu, Y., Yang, X., He, Z., Li, J., Li, Y., Wu, Y., Manyande, A., Feng, M., and Xiang, H. (2023). Spinal cord injury: Global burden from 1990 to 2019 and projections up to 2030 using Bayesian age-period-cohort analysis. Front. Neurol., 14.","DOI":"10.3389\/fneur.2023.1304153"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.46292\/sci2702-1","article-title":"International Standards for Neurological Classification of Spinal Cord Injury: Revised 2019","volume":"27","author":"Rupp","year":"2021","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.46292\/sci22-00036","article-title":"The International Standards for Neurological Classification of Spinal Cord Injury: Classification Accuracy and Challenges","volume":"29","author":"Snider","year":"2023","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1089\/neu.2004.21.1371","article-title":"Targeting recovery: Priorities of the spinal cord-injured population","volume":"21","author":"Anderson","year":"2004","journal-title":"J. Neurotrauma"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1089\/neu.2011.2226","article-title":"Spinal Cord Injury Rehabilitation Evidence Scire Research Team. The health and life priorities of individuals with spinal cord injury: A systematic review","volume":"29","author":"Simpson","year":"2012","journal-title":"J. Neurotrauma"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1089\/neu.2016.4423","article-title":"Functional Priorities in Persons with Spinal Cord Injury: Using Discrete Choice Experiments to Determine Preferences","volume":"33","author":"Lo","year":"2016","journal-title":"J. Neurotrauma"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1038\/sj.sc.3101638","article-title":"Survey of the needs of patients with spinal cord injury: Impact and priority for improvement in hand function in tetraplegics","volume":"42","author":"Snoek","year":"2004","journal-title":"Spinal Cord"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s13311-018-0642-3","article-title":"Robotic Rehabilitation and Spinal Cord Injury: A Narrative Review","volume":"15","author":"Mekki","year":"2018","journal-title":"Neurotherapeutics"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Morone, G., de Sire, A., Martino Cinnera, A., Paci, M., Perrero, L., Invernizzi, M., Lippi, L., Agostini, M., Aprile, I., and Casanova, E. (2021). Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review. Brain Sci., 11.","DOI":"10.3390\/brainsci11121630"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12984-022-01003-9","article-title":"Overground robotic training effects on walking and secondary health conditions in individuals with spinal cord injury: Systematic review","volume":"19","author":"Tamburella","year":"2022","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.wneu.2024.01.167","article-title":"Exoskeleton-Assisted Rehabilitation and Neuroplasticity in Spinal Cord Injury","volume":"185","author":"He","year":"2024","journal-title":"World Neurosurg."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.5535\/arm.230039","article-title":"Robot-Assisted Gait Training in Individuals with Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","volume":"48","author":"Park","year":"2024","journal-title":"Ann. Rehabil. Med."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s12984-024-01365-2","article-title":"Exoskeleton-based exercises for overground gait and balance rehabilitation in spinal cord injury: A systematic review of dose and dosage parameters","volume":"21","author":"Nepomuceno","year":"2024","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.brainresbull.2008.09.018","article-title":"Robotic training and spinal cord plasticity","volume":"78","author":"Edgerton","year":"2009","journal-title":"Brain Res. Bull."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1177\/1073858417699790","article-title":"The Human Central Pattern Generator for Locomotion: Does It Exist and Contribute to Walking?","volume":"23","author":"Minassian","year":"2017","journal-title":"Neuroscientist"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1743-0003-10-5","article-title":"The physiological basis of neurorehabilitation--locomotor training after spinal cord injury","volume":"10","author":"Hubli","year":"2013","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1177\/1545968312439687","article-title":"Should body weight-supported treadmill training and robotic-assistive steppers for locomotor training trot back to the starting gate?","volume":"26","author":"Dobkin","year":"2012","journal-title":"Neurorehabil Neural Repair."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1743-0003-6-20","article-title":"Review of control strategies for robotic movement training after neurologic injury","volume":"6","author":"Reinkensmeyer","year":"2009","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev-neuro-061010-113746","article-title":"Recovery of locomotion after spinal cord injury: Some facts and mechanisms","volume":"34","author":"Rossignol","year":"2011","journal-title":"Annu. Rev. Neurosci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrneurol.2009.227","article-title":"Behavior of spinal neurons deprived of supraspinal input","volume":"6","author":"Dietz","year":"2010","journal-title":"Nat. Rev. Neurol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1038\/s41591-019-0475-6","article-title":"Spinal cord repair: Advances in biology and technology","volume":"25","author":"Courtine","year":"2019","journal-title":"Nat. Med."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainres.2012.12.034","article-title":"Functional brain reorganization after spinal cord injury: Systematic review of animal and human studies","volume":"1504","author":"Nardone","year":"2013","journal-title":"Brain Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1093\/brain\/awr093","article-title":"Disability, atrophy and cortical reorganization following spinal cord injury","volume":"134","author":"Freund","year":"2011","journal-title":"Brain"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Calderone, A., Cardile, D., De Luca, R., Quartarone, A., Corallo, F., and Calabr\u00f2, R.S. (2024). Brain Plasticity in Patients with Spinal Cord Injuries: A Systematic Review. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25042224"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Braun, N., Debener, S., Spychala, N., Bongartz, E., S\u00f6r\u00f6s, P., M\u00fcller, H.H.O., and Philipsen, A. (2018). The Senses of Agency and Ownership: A Review. Front. Psychol., 9.","DOI":"10.3389\/fpsyg.2018.00535"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Turner, D.L., Ramos-Murguialday, A., Birbaumer, N., Hoffmann, U., and Luft, A. (2013). Neurophysiology of robot-mediated training and therapy: A perspective for future use in clinical populations. Front. Neurol., 4.","DOI":"10.3389\/fneur.2013.00184"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"S255","DOI":"10.1097\/PHM.0b013e31826bcdc1","article-title":"Robotic assessment of upper limb motor function after stroke","volume":"91","author":"Balasubramanian","year":"2012","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/0269215514536411","article-title":"Effects of training on upper limb function after cervical spinal cord injury: A systematic review","volume":"29","author":"Lu","year":"2015","journal-title":"Clin. Rehabil."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/sc.2008.113","article-title":"Systematic review of the effects of exercise therapy on the upper extremity of patients with spinal-cord injury","volume":"47","author":"Kloosterman","year":"2009","journal-title":"Spinal Cord"},{"key":"ref_31","first-page":"5975400","article-title":"Effect of a robotic rehabilitation device on upper limb function in a sub-acute cervical spinal cord injury population","volume":"2011","author":"Zariffa","year":"2011","journal-title":"IEEE Int. Conf. Rehabil. Robot."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/sc.2011.104","article-title":"Feasibility and efficacy of upper limb robotic rehabilitation in a subacute cervical spinal cord injury population","volume":"50","author":"Zariffa","year":"2012","journal-title":"Spinal Cord"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3233\/NRE-130928","article-title":"Improved motor performance in chronic spinal cord injury following upper-limb robotic training","volume":"33","author":"Cortes","year":"2013","journal-title":"NeuroRehabilitation"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/sc.2014.250","article-title":"Robot-assisted task-oriented upper extremity skill training in cervical spinal cord injury: A feasibility study","volume":"53","author":"Vanmulken","year":"2015","journal-title":"Spinal Cord"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"S171","DOI":"10.1097\/PHM.0000000000000815","article-title":"Robot-Assisted Training of Arm and Hand Movement Shows Functional Improvements for Incomplete Cervical Spinal Cord Injury","volume":"96","author":"Francisco","year":"2017","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Frullo, J.M., Elinger, J., Pehlivan, A.U., Fitle, K., Nedley, K., Francisco, G.E., Sergi, F., and O\u2019Malley, M.K. (2017). Effects of Assist-As-Needed Upper Extremity Robotic Therapy after Incomplete Spinal Cord Injury: A Parallel-Group Controlled Trial. Front. Neurorobot., 11.","DOI":"10.3389\/fnbot.2017.00026"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/s41393-018-0190-z","article-title":"Clinical efficacy of upper limb robotic therapy in people with tetraplegia: A pilot randomized controlled trial","volume":"57","author":"Kim","year":"2019","journal-title":"Spinal Cord"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"445","DOI":"10.5535\/arm.2019.43.4.445","article-title":"Effects of Combined Upper Limb Robotic Therapy in Patients with Tetraplegic Spinal Cord Injury","volume":"43","author":"Jung","year":"2019","journal-title":"Ann. Rehabil. Med."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12984-020-00660-y","article-title":"Home-based rehabilitation using a soft robotic hand glove device leads to improvement in hand function in people with chronic spinal cord injury:a pilot study","volume":"17","author":"Osuagwu","year":"2020","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s12984-018-0391-x","article-title":"Assisting hand function after spinal cord injury with a fabric-based soft robotic glove","volume":"15","author":"Cappello","year":"2018","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1080\/17483107.2018.1425747","article-title":"Robot-assisted upper extremity rehabilitation for cervical spinal cord injuries: A systematic scoping review","volume":"13","author":"Singh","year":"2018","journal-title":"Disabil. Rehabil. Assist. Technol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.pmr.2018.12.008","article-title":"Robot-assisted Therapy for the Upper Limb after Cervical Spinal Cord Injury","volume":"30","author":"Yozbatiran","year":"2019","journal-title":"Phys. Med. Rehabil. Clin. N. Am."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Lozano-Berrio, V., Alcobendas-Maestro, M., Polonio-L\u00f3pez, B., Gil-Agudo, A., de la Pe\u00f1a-Gonz\u00e1lez, A., and de Los Reyes-Guzm\u00e1n, A. (2022). The Impact of Robotic Therapy on the Self-Perception of Upper Limb Function in Cervical Spinal Cord Injury: A Pilot Randomized Controlled Trial. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19106321"},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Ho, J.S., Ko, K.S., Law, S.W., and Man, G.C. (2023). The effectiveness of robotic-assisted upper limb rehabilitation to improve upper limb function in patients with cervical spinal cord injuries: A systematic literature review. Front. Neurol., 14.","DOI":"10.3389\/fneur.2023.1126755"},{"key":"ref_45","first-page":"455","article-title":"Clinical effectiveness and safety of powered exoskeleton-assisted walking in patients with spinal cord injury: Systematic review with meta-analysis","volume":"9","author":"Miller","year":"2016","journal-title":"Med. Devices"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1186\/s12984-015-0074-9","article-title":"Spinal Cord Injury Research Evidence (SCIRE) Research Team. Gait speed using powered robotic exoskeletons after spinal cord injury: A systematic review and correlational study","volume":"12","author":"Louie","year":"2015","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3109\/17483107.2015.1080766","article-title":"Exoskeletons\u2019 design and usefulness evidence according to a systematic review of lower limb exoskeletons used for functional mobility by people with spinal cord injury","volume":"11","author":"Lajeunesse","year":"2016","journal-title":"Disabil. Rehabil. Assist. Technol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1016\/j.apmr.2017.05.015","article-title":"Robot-Assisted Training for People with Spinal Cord Injury: A Meta-Analysis","volume":"98","author":"Cheung","year":"2017","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jocn.2021.07.019","article-title":"Robot-assisted gait training in individuals with spinal cord injury: A systematic review for the clinical effectiveness of Lokomat","volume":"91","author":"Alashram","year":"2021","journal-title":"J. Clin. Neurosci."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"2102785","DOI":"10.1155\/2020\/2102785","article-title":"Effects of Robot-Assisted Gait Training in Individuals with Spinal Cord Injury: A Meta-analysis","volume":"2020","author":"Fang","year":"2020","journal-title":"BioMed Res. Int."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/NPT.0000000000000303","article-title":"And the Locomotor CPG Appraisal Team. Clinical Practice Guideline to Improve Locomotor Function Following Chronic Stroke, Incomplete Spinal Cord Injury, and Brain Injury","volume":"44","author":"Hornby","year":"2020","journal-title":"J. Neurol. Phys. Ther."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1743-0003-11-4","article-title":"Strength training versus robot-assisted gait training after incomplete spinal cord injury: A randomized pilot study in patients depending on walking assistance","volume":"11","year":"2014","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"S174","DOI":"10.1016\/j.pmrj.2018.06.005","article-title":"Exoskeleton and End-Effector Robots for Upper and Lower Limbs Rehabilitation: Narrative Review","volume":"10","author":"Molteni","year":"2018","journal-title":"PM R"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1080\/10790268.2018.1426236","article-title":"The effects of robot assisted gait training on temporal-spatial characteristics of people with spinal cord injuries: A systematic review","volume":"41","author":"Hayes","year":"2018","journal-title":"J. Spinal Cord Med."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/s40814-018-0247-y","article-title":"Exoskeleton-assisted gait training to improve gait in individuals with spinal cord injury: A pilot randomized study","volume":"4","author":"Chang","year":"2018","journal-title":"Pilot Feasibility Stud."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1080\/17483107.2017.1413145","article-title":"Satisfaction and perceptions of long-term manual wheelchair users with a spinal cord injury upon completion of a locomotor training program with an overground robotic exoskeleton","volume":"14","author":"Gagnon","year":"2019","journal-title":"Disabil. Rehabil. Assist. Technol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12984-019-0565-1","article-title":"Perspectives of people with spinal cord injury learning to walk using a powered exoskeleton","volume":"16","author":"Manns","year":"2019","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1310\/sci17-00014","article-title":"Initial Outcomes from a Multicenter Study Utilizing the Indego Powered Exoskeleton in Spinal Cord Injury","volume":"24","author":"Tefertiller","year":"2018","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1310\/sci17-00055","article-title":"Examining the Effects of a Powered Exoskeleton on Quality of Life and Secondary Impairments in People Living with Spinal Cord Injury","volume":"24","author":"Juszczak","year":"2018","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_60","first-page":"111","article-title":"Use of the robot assisted gait therapy in rehabilitation of patients with stroke and spinal cord injury","volume":"48","author":"Sale","year":"2012","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"520","DOI":"10.2340\/16501977-0538","article-title":"Effectiveness of robot-assisted gait training in persons with spinal cord injury: A systematic review","volume":"42","author":"Swinnen","year":"2010","journal-title":"J. Rehabil. Med."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.12786\/bn.2020.13.e6","article-title":"Feasibility of Robot-Assisted Gait Training with an End-Effector Type Device for Various Neurologic Disorders","volume":"13","author":"Choi","year":"2020","journal-title":"Brain Neurorehabil"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Shin, J.C., Jeon, H.R., Kim, D., Cho, S.I., Min, W.K., Lee, J.S., Oh, D.S., and Yoo, J. (2021). Effects on the Motor Function, Proprioception, Balance, and Gait Ability of the End-Effector Robot-Assisted Gait Training for Spinal Cord Injury Patients. Brain Sci., 11.","DOI":"10.3390\/brainsci11101281"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1007\/s10439-020-02611-z","article-title":"Robotic Rehabilitation in Spinal Cord Injury: A Pilot Study on End-Effectors and Neurophysiological Outcomes","volume":"49","author":"Filoni","year":"2021","journal-title":"Ann. BioMed Eng."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"335","DOI":"10.3233\/NRE-230085","article-title":"Effects of end-effector robot-assisted gait training on gait ability, muscle strength, and balance in patients with spinal cord injury","volume":"53","author":"Shin","year":"2023","journal-title":"NeuroRehabilitation"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1310\/sci2102-93","article-title":"Mobility Outcomes Following Five Training Sessions with a Powered Exoskeleton","volume":"21","author":"Hartigan","year":"2015","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"745","DOI":"10.23736\/S1973-9087.18.04819-0","article-title":"Training for mobility with exoskeleton robot in spinal cord injury patients: A pilot study","volume":"54","author":"Sale","year":"2018","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.apmr.2019.09.005","article-title":"The Safety and Feasibility of Exoskeletal-Assisted Walking in Acute Rehabilitation After Spinal Cord Injury","volume":"101","author":"McIntosh","year":"2020","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Sale, P., Russo, E.F., Russo, M., Masiero, S., Piccione, F., Calabr\u00f2, R.S., and Filoni, S. (2016). Effects on mobility training and de-adaptations in subjects with Spinal Cord Injury due to a Wearable Robot: A preliminary report. BMC Neurol., 16.","DOI":"10.1186\/s12883-016-0536-0"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1016\/j.apmr.2014.04.026","article-title":"Understanding therapeutic benefits of overground bionic ambulation: Exploratory case series in persons with chronic, complete spinal cord injury","volume":"95","author":"Kressler","year":"2014","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/s41393-017-0013-7","article-title":"Gait training after spinal cord injury: Safety, feasibility and gait function following 8 weeks of training with the exoskeletons from Ekso Bionics","volume":"56","author":"Frotzler","year":"2018","journal-title":"Spinal Cord"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.apmr.2019.11.010","article-title":"Exoskeletal-Assisted Walking During Acute Inpatient Rehabilitation Leads to Motor and Functional Improvement in Persons with Spinal Cord Injury: A Pilot Study","volume":"101","author":"Tsai","year":"2020","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.rehab.2017.12.008","article-title":"Cardiorespiratory demand and rate of perceived exertion during overground walking with a robotic exoskeleton in long-term manual wheelchair users with chronic spinal cord injury: A cross-sectional study","volume":"61","author":"Escalona","year":"2018","journal-title":"Ann. Phys. Rehabil. Med."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s12984-018-0453-0","article-title":"Overground walking with a robotic exoskeleton elicits trunk muscle activity in people with high-thoracic motor-complete spinal cord injury","volume":"15","author":"Alamro","year":"2018","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"84","DOI":"10.2340\/16501977-2173","article-title":"Effect on body composition and bone mineral density of walking with a robotic exoskeleton in adults with chronic spinal cord injury","volume":"49","author":"Karelis","year":"2017","journal-title":"J. Rehabil. Med."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1080\/10790268.2017.1314900","article-title":"Neuromechanical adaptations during a robotic powered exoskeleton assisted walking session","volume":"41","author":"Ramanujam","year":"2018","journal-title":"J. Spinal Cord Med."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/NPT.0000000000000262","article-title":"Cardiometabolic Challenges Provided by Variable Assisted Exoskeletal Versus Overground Walking in Chronic Motor-incomplete Paraplegia: A Case Series","volume":"43","author":"Kressler","year":"2019","journal-title":"J. Neurol. Phys. Ther."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"806","DOI":"10.2340\/16501977-2372","article-title":"Exoskeleton gait training after spinal cord injury: An exploratory study on secondary health conditions","volume":"50","author":"Baunsgaard","year":"2018","journal-title":"J. Rehabil. Med."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3233\/NRE-161358","article-title":"Walking with a powered robotic exoskeleton: Subjective experience, spasticity and pain in spinal cord injured persons","volume":"39","author":"Stampacchia","year":"2016","journal-title":"NeuroRehabilitation"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1310\/sci2102-100","article-title":"Assessment of In-Hospital Walking Velocity and Level of Assistance in a Powered Exoskeleton in Persons with Spinal Cord Injury","volume":"21","author":"Yang","year":"2015","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_81","doi-asserted-by":"crossref","unstructured":"Pournajaf, S., Morone, G., Felzani, G., Pellicciari, L., Cocco, E.S., Manzia, C.M., Simoncini, L., Calabr\u00f2, R.S., and Franceschini, M. (2026). Wearable powered overground exoskeleton reduces dose-dependently the spasticity in individuals with spinal cord injury. Spinal Cord.","DOI":"10.1038\/s41393-026-01181-6"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/0269215515575166","article-title":"Lower-limb exoskeletons for individuals with chronic spinal cord injury: Findings from a feasibility study","volume":"30","author":"Benson","year":"2016","journal-title":"Clin. Rehabil."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"209","DOI":"10.23736\/S1973-9087.18.05308-X","article-title":"Assistive powered exoskeleton for complete spinal cord injury: Correlations between walking ability and exoskeleton control","volume":"55","author":"Guanziroli","year":"2019","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1097\/PHM.0b013e318269d9a3","article-title":"The ReWalk powered exoskeleton to restore ambulatory function to individuals with thoracic-level motor-complete spinal cord injury","volume":"91","author":"Esquenazi","year":"2012","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12984-016-0142-9","article-title":"Accelerometry-enabled measurement of walking performance with a robotic exoskeleton: A pilot study","volume":"13","author":"Lonini","year":"2016","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1682\/JRRD.2014.02.0060","article-title":"Heart rate and oxygen demand of powered exoskeleton-assisted walking in persons with paraplegia","volume":"52","author":"Asselin","year":"2015","journal-title":"J. Rehabil. Res. Dev."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/s41393-019-0392-z","article-title":"Changes in bowel function following exoskeletal-assisted walking in persons with spinal cord injury: An observational pilot study","volume":"58","author":"Chun","year":"2020","journal-title":"Spinal Cord"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1179\/2045772313Y.0000000126","article-title":"Vertical ground reaction force-based analysis of powered exoskeleton-assisted walking in persons with motor-complete paraplegia","volume":"36","author":"Fineberg","year":"2013","journal-title":"J. Spinal Cord Med."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1310\/sci2102-122","article-title":"Acute Cardiorespiratory and Metabolic Responses During Exoskeleton-Assisted Walking Overground Among Persons with Chronic Spinal Cord Injury","volume":"21","author":"Evans","year":"2015","journal-title":"Top. Spinal Cord Inj. Rehabil."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/sc.2016.46","article-title":"Pain, spasticity and quality of life in individuals with traumatic spinal cord injury in Denmark","volume":"54","author":"Andresen","year":"2016","journal-title":"Spinal Cord"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/sc.2011.150","article-title":"Secondary health conditions in individuals aging with SCI: Terminology, concepts and analytic approaches","volume":"50","author":"Jensen","year":"2012","journal-title":"Spinal Cord"},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Budd, M.A., Gater, J., and Channell, I. (2022). Psychosocial Consequences of Spinal Cord Injury: A Narrative Review. J. Pers. Med., 12.","DOI":"10.3390\/jpm12071178"},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/sc.2008.115","article-title":"Psychological morbidity and spinal cord injury: A systematic review","volume":"47","author":"Craig","year":"2009","journal-title":"Spinal Cord"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/sc.2011.182","article-title":"Psychosocial issues in spinal cord injury: A review","volume":"50","author":"Post","year":"2012","journal-title":"Spinal Cord"},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"jrm00217","DOI":"10.2340\/16501977-2858","article-title":"Participation and quality of life in persons living with spinal cord injury in Norway","volume":"53","author":"Halvorsen","year":"2021","journal-title":"J. Rehabil. Med."},{"key":"ref_96","doi-asserted-by":"crossref","unstructured":"Hu, X., Feng, J., Lu, J., Pang, R., Zhang, A., Liu, J., Gou, X., Bai, X., Wang, J., and Chang, C. (2024). Effects of exoskeleton-assisted walking on bowel function in motor-complete spinal cord injury patients: Involvement of the brain-gut axis, a pilot study. Front. Neurosci., 18.","DOI":"10.3389\/fnins.2024.1395671"},{"key":"ref_97","doi-asserted-by":"crossref","unstructured":"Nistor-Cseppento, C.D., Gherle, A., Negrut, N., Bungau, S.G., Sabau, A.M., Radu, A.F., Bungau, A.F., Tit, D.M., Uivaraseanu, B., and Ghitea, T.C. (2022). The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications. Medicina, 58.","DOI":"10.3390\/medicina58101447"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s12984-021-00882-8","article-title":"Functional electrical stimulation cycling exercise after spinal cord injury: A systematic review of health and fitness-related outcomes","volume":"18","author":"Valentino","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/10790268.2020.1763713","article-title":"Changes in spasticity following functional electrical stimulation cycling in patients with spinal cord injury: A systematic review","volume":"45","author":"Alashram","year":"2022","journal-title":"J. Spinal Cord Med."},{"key":"ref_100","first-page":"289","article-title":"An integrated gait rehabilitation training based on Functional Electrical Stimulation cycling and overground robotic exoskeleton in complete spinal cord injury patients: Preliminary results","volume":"2017","author":"Mazzoleni","year":"2017","journal-title":"IEEE Int. Conf. Rehabil. Robot."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"927","DOI":"10.31616\/asj.2018.12.5.927","article-title":"Efficacy of Virtual Reality in Upper Limb Rehabilitation in Patients with Spinal Cord Injury: A Pilot Randomized Controlled Trial","volume":"12","author":"Prasad","year":"2018","journal-title":"Asian Spine J."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"30383","DOI":"10.1038\/srep30383","article-title":"Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients","volume":"6","author":"Donati","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_103","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-Larraz, E., Trincado-Alonso, F., Rajasekaran, V., P\u00e9rez-Nombela, S., Del-Ama, A.J., Aranda, J., Minguez, J., Gil-Agudo, A., and Montesano, L. (2016). Control of an Ambulatory Exoskeleton with a Brain-Machine Interface for Spinal Cord Injury Gait Rehabilitation. Front. Neurosci., 10.","DOI":"10.3389\/fnins.2016.00359"},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Naro, A., Billeri, L., Balletta, T., Lauria, P., Onesta, M.P., and Calabr\u00f2, R.S. (2022). Finding the Way to Improve Motor Recovery of Patients with Spinal Cord Lesions: A Case-Control Pilot Study on a Novel Neuromodulation Approach. Brain Sci., 12.","DOI":"10.3390\/brainsci12010119"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/S1474-4422(19)30321-7","article-title":"An exoskeleton controlled by an epidural wireless brain-machine interface in a tetraplegic patient: A proof-of-concept demonstration","volume":"18","author":"Benabid","year":"2019","journal-title":"Lancet Neurol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1177\/15459683221138751","article-title":"Brain-Computer Interface-Controlled Exoskeletons in Clinical Neurorehabilitation: Ready or Not?","volume":"36","author":"Colucci","year":"2022","journal-title":"Neurorehabil Neural Repair."},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Rupp, R. (2014). Challenges in clinical applications of brain computer interfaces in individuals with spinal cord injury. Front. Neuroeng., 7.","DOI":"10.3389\/fneng.2014.00038"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"401","DOI":"10.3233\/NRE-161371","article-title":"Transcranial direct current stimulation (tDCS) of the primary motor cortex and robot-assisted arm training in chronic incomplete cervical spinal cord injury: A proof of concept sham-randomized clinical study","volume":"39","author":"Yozbatiran","year":"2016","journal-title":"NeuroRehabilitation"},{"key":"ref_109","first-page":"161","article-title":"Combined effects of cerebellar transcranial direct current stimulation and transcutaneous spinal direct current stimulation on robot-assisted gait training in patients with chronic brain stroke: A pilot, single blind, randomized controlled trial","volume":"36","author":"Picelli","year":"2018","journal-title":"Restor. Neurol. Neurosci."},{"key":"ref_110","doi-asserted-by":"crossref","unstructured":"Simonetti, D., Zollo, L., Milighetti, S., Miccinilli, S., Bravi, M., Ranieri, F., Magrone, G., Guglielmelli, E., Di Lazzaro, V., and Sterzi, S. (2017). Literature Review on the Effects of tDCS Coupled with Robotic Therapy in Post Stroke Upper Limb Rehabilitation. Front. Hum. Neurosci., 11.","DOI":"10.3389\/fnhum.2017.00268"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1055\/s-0041-1725137","article-title":"Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation","volume":"41","author":"Young","year":"2021","journal-title":"Semin. Neurol."},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Wardhana, D.P.W., Maliawan, S., Mahadewa, T.G.B., Rosyidi, R.M., and Wiranata, S. (2023). The Impact of Machine Learning and Robot-Assisted Gait Training on Spinal Cord Injury: A Systematic Review and Meta-Analysis. J. Clin. Med., 12.","DOI":"10.3390\/jcm12237230"},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Calderone, A., Latella, D., Bonanno, M., Quartarone, A., Mojdehdehbaher, S., Celesti, A., and Calabr\u00f2, R.S. (2024). Towards Transforming Neurorehabilitation: The Impact of Artificial Intelligence on Diagnosis and Treatment of Neurological Disorders. Biomedicines, 12.","DOI":"10.3390\/biomedicines12102415"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"215","DOI":"10.13004\/kjnt.2024.20.e43","article-title":"Using Artificial Intelligence in the Comprehensive Management of Spinal Cord Injury","volume":"20","author":"Kim","year":"2024","journal-title":"Korean J. Neurotrauma"},{"key":"ref_115","first-page":"e94273","article-title":"AI-Driven Rehabilitation Robotics: Advancements in and Impacts on Patient Recovery","volume":"17","author":"Abbas","year":"2025","journal-title":"Cureus"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s12984-023-01158-z","article-title":"Exoskeleton-based training improves walking independence in incomplete spinal cord injury patients: Results from a randomized controlled trial","volume":"20","author":"Pons","year":"2023","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1038\/s41393-022-00751-8","article-title":"Walking improvement in chronic incomplete spinal cord injury with exoskeleton robotic training (WISE): A randomized controlled trial","volume":"60","author":"Edwards","year":"2022","journal-title":"Spinal Cord"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"838","DOI":"10.3906\/sag-1809-7","article-title":"Early term effects of robotic assisted gait training on ambulation and functional capacity in patients with spinal cord injury","volume":"49","year":"2019","journal-title":"Turk. J. Med. Sci."},{"key":"ref_119","doi-asserted-by":"crossref","unstructured":"Tarnacka, B., Korczy\u0144ski, B., and Frasu\u0144ska, J. (2023). Impact of Robotic-Assisted Gait Training in Subacute Spinal Cord Injury Patients on Outcome Measure. Diagnostics, 13.","DOI":"10.3390\/diagnostics13111966"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1080\/10790268.2023.2214482","article-title":"The efficacy of exoskeleton robotic training on ambulation recovery in patients with spinal cord injury: A meta-analysis","volume":"47","author":"Liu","year":"2024","journal-title":"J. Spinal Cord Med."},{"key":"ref_121","first-page":"1","article-title":"The use of exoskeleton robotic training on lower extremity function in spinal cord injuries: A systematic review","volume":"65","author":"Moriarty","year":"2024","journal-title":"J. Orthop."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s12984-025-01649-1","article-title":"Comparative efficacy of robotic exoskeleton and conventional gait training in patients with spinal cord injury: A meta-analysis of randomized controlled trials","volume":"22","author":"Liu","year":"2025","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_123","doi-asserted-by":"crossref","unstructured":"Nadorf, F., Wright, M.A., L\u00f3pez-Matas, H., Porras, E., Carnicero-Carmona, A., Hensel, C., Franz, S., Weidner, N., Vidal, J., and Opisso, E. (2024). User-centered design of a personal-use exoskeleton: A clinical investigation on the feasibility and usability of the ABLE Exoskeleton device for individuals with spinal cord injury to perform skills for home and community environments. Front. Neurosci., 18.","DOI":"10.3389\/fnins.2024.1437358"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/02692155231164092","article-title":"A systematic review of the determinants of implementation of a locomotor training program using a powered exoskeleton for individuals with a spinal cord injury","volume":"37","author":"Charette","year":"2023","journal-title":"Clin. Rehabil."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"Onate, D., Hogan, C., Fitzgerald, K., White, K.T., and Tansey, K. (2024). Recommendations for clinical decision-making when offering exoskeletons for community use in individuals with spinal cord injury. Front. Rehabil. Sci., 5.","DOI":"10.3389\/fresc.2024.1428708"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1111\/aor.14925","article-title":"Consumer views of functional electrical stimulation and robotic exoskeleton in SCI rehabilitation: A mini review","volume":"49","author":"Pei","year":"2025","journal-title":"Artif. Organs"},{"key":"ref_127","doi-asserted-by":"crossref","unstructured":"de Seta, V., and Romeni, S. (2025). Multimodal closed-loop strategies for gait recovery after spinal cord injury and stroke via the integration of robotics and neuromodulation. Front. Neurosci., 19.","DOI":"10.3389\/fnins.2025.1569148"},{"key":"ref_128","doi-asserted-by":"crossref","unstructured":"Algaba-Vidoy, M., P\u00e9rez-Nombela, S., Meg\u00eda-Garc\u00eda, \u00c1., Montero-Pardo, C., Redondo-Gal\u00e1n, C., de Los Reyes-Guzm\u00e1n, A., Serrano-Mu\u00f1oz, D., G\u00f3mez-Soriano, J., Del-Ama, A.J., and Moreno, J.C. (2025). Exploring the feasibility of combining transcutaneous electrical spinal cord stimulation and overground robotic exoskeleton for gait rehabilitation in patients with spinal cord injury. Front. Neurol., 16.","DOI":"10.3389\/fneur.2025.1648616"},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1002\/ana.78144","article-title":"Brain-Computer Interface-Controlled Exoskeleton Training for Lower-Limb Rehabilitation in Spinal Cord Injury: A Pilot Randomized Clinical Trial","volume":"99","author":"Hu","year":"2026","journal-title":"Ann. Neurol."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"e70183","DOI":"10.1111\/ejn.70183","article-title":"Brain-Computer Interfaces in Spinal Cord Injury: A Promising Therapeutic Strategy","volume":"62","author":"Li","year":"2025","journal-title":"Eur. J. Neurosci."},{"key":"ref_131","first-page":"e51989","article-title":"Effect of Transcranial Direct Current Stimulation on Lower Extremity Muscle Strength, Quality of Life, and Functional Recovery in Individuals with Incomplete Spinal Cord Injury: A Randomized Controlled Study","volume":"16","author":"Nijhawan","year":"2024","journal-title":"Cureus"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s12984-021-00880-w","article-title":"Exoskeleton-assisted walking improves pulmonary function and walking parameters among individuals with spinal cord injury: A randomized controlled pilot study","volume":"18","author":"Xiang","year":"2021","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/s41393-020-0423-9","article-title":"The safety and feasibility of a new rehabilitation robotic exoskeleton for assisting individuals with lower extremity motor complete lesions following spinal cord injury (SCI): An observational study","volume":"58","author":"Xiang","year":"2020","journal-title":"Spinal Cord"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"E15","DOI":"10.3171\/2017.2.FOCUS171","article-title":"Against the odds: What to expect in rehabilitation of chronic spinal cord injury with a neurologically controlled Hybrid Assistive Limb exoskeleton. A subgroup analysis of 55 patients according to age and lesion level","volume":"42","author":"Zieriacks","year":"2017","journal-title":"Neurosurg. Focus"},{"key":"ref_135","first-page":"529","article-title":"Impact of locomotion training with a neurologic controlled hybrid assistive limb (HAL) exoskeleton on neuropathic pain and health related quality of life (HRQoL) in chronic SCI: A case study","volume":"11","author":"Cruciger","year":"2016","journal-title":"Disabil. Rehabil. Assist. Technol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s12984-015-0058-9","article-title":"HAL\u00ae exoskeleton training improves walking parameters and normalizes cortical excitability in primary somatosensory cortex in spinal cord injury patients","volume":"12","author":"Aach","year":"2015","journal-title":"J. Neuroeng. Rehabil."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1016\/j.spinee.2014.03.042","article-title":"Voluntary driven exoskeleton as a new tool for rehabilitation in chronic spinal cord injury: A pilot study","volume":"14","author":"Aach","year":"2014","journal-title":"Spine J."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.apmr.2004.08.004","article-title":"Effectiveness of automated locomotor training in patients with chronic incomplete spinal cord injury: A multicenter trial","volume":"86","author":"Wirz","year":"2005","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"ref_139","doi-asserted-by":"crossref","unstructured":"Cano-de-la-Cuerda, R., Bl\u00e1zquez-Fern\u00e1ndez, A., Marcos-Ant\u00f3n, S., S\u00e1nchez-Herrera-Baeza, P., Fern\u00e1ndez-Gonz\u00e1lez, P., Collado-V\u00e1zquez, S., Jim\u00e9nez-Antona, C., and Laguarta-Val, S. (2024). Economic Cost of Rehabilitation with Robotic and Virtual Reality Systems in People with Neurological Disorders: A Systematic Review. J. Clin. Med., 13.","DOI":"10.3390\/jcm13061531"}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/16\/7\/732\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:40:05Z","timestamp":1784191205000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/16\/7\/732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,11]]},"references-count":139,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2026,7]]}},"alternative-id":["brainsci16070732"],"URL":"https:\/\/doi.org\/10.3390\/brainsci16070732","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,11]]}}}