{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:01:02Z","timestamp":1786978862111,"version":"build-2736575974"},"reference-count":52,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sci.","Brain Sciences"],"abstract":"<jats:p>Background: Acute confusional state, or delirium, is a common neuropsychiatric disorder in older adults, particularly in emergency departments. It is associated with high morbidity and mortality, as well as difficult detection. Its early identification is crucial to prevent complications and improve prognosis. This study aims to identify and analyze available strategies for the early diagnosis of delirium in geriatric patients in emergency departments. Methods: A literature review and meta-analysis were conducted between 2020 and 2026 using the PubMed, Scopus, Web of Science, CINAHL, and Cochrane databases (PRISMA 2020). To estimate the prevalence of patients with delirium in emergency departments, a meta-analysis was performed using Stats Direct statistical software (Version 4). Methodological quality was evaluated according to the Oxford Centre for Evidence-Based Medicine levels of evidence. Results: Eleven studies were included, demonstrating that delirium in emergency departments is highly prevalent among older adults, particularly those with dementia, polypharmacy, or functional impairment. The 4AT scale was the most frequently used screening tool, notable for its strong sensitivity. Hypoactive delirium emerged as the most common subtype and carried the poorest prognosis. Furthermore, its presence was associated with longer hospital stays, increased complications, and higher mortality rates, while a lack of training among healthcare staff continues to limit early detection. The meta-analysis detected no publication bias and revealed a 20.6% prevalence of delirium among patients in emergency departments. Conclusions: One in five patients attending the emergency department presents with delirium. Delirium in geriatric emergency care demands a structured clinical response grounded in prevention, early detection, and professional training. Integrating validated diagnostic tools and reinforcing the role of nursing professionals are key to improving patient outcomes and safety.<\/jats:p>","DOI":"10.3390\/brainsci16080864","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T13:42:17Z","timestamp":1786974137000},"page":"864","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Early Diagnosis of Delirium in Geriatric Patients in Emergency Departments: A Systematic Review and Meta-Analysis"],"prefix":"10.3390","volume":"16","author":[{"given":"Paula","family":"Albusac-Olivares","sequence":"first","affiliation":[{"name":"Sierra de Cazorla High-Resolution Hospital, Andalusian Health Service, Carretera A-319 Cazorla-Peal del Becerro, s\/n, 23470 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Chami-Pe\u00f1a","sequence":"additional","affiliation":[{"name":"Centro de Salud de Santa Fe, Distrito Sanitario Granada-Metropolitano, Servicio Andaluz de Salud, Calle Virgen de la Consolaci\u00f3n, 12, 18015 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M.","family":"Guti\u00e9rrez-Pastor","sequence":"additional","affiliation":[{"name":"San Cecilio Clinical University Hospital, Andalusian Health Service, Av. del Conocimiento s\/n, 18016 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Caballero-V\u00e1zquez","sequence":"additional","affiliation":[{"name":"DiagnosticLung Cancer Unit, Broncopleural Techniques and Interventional Pulmonology Departament, Hospital Universitario Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Institute for Biosanitary Research (ibs.GRANADA), 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5299-0710","authenticated-orcid":false,"given":"Miguel","family":"Quesada-Caballero","sequence":"additional","affiliation":[{"name":"Institute for Biosanitary Research (ibs.GRANADA), 18012 Granada, Spain"},{"name":"Centro de Salud Albayda La Cruz, Distrito Sanitario Granada-Metropolitano, Servicio Andaluz de Salud, Calle Virgen de la Consolaci\u00f3n, 12, 18015 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4133-0092","authenticated-orcid":false,"given":"Nora","family":"Suleiman-Martos","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Granada, Av. Ilustraci\u00f3n 60, 18016 Granada, Spain"},{"name":"Brain, Mind and Behaviour Research Center (CIMCYC), University of Granada, Campus Universitario de Cartuja s\/n, 18011 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3012-3410","authenticated-orcid":false,"given":"Guillermo A.","family":"Ca\u00f1adas-De la Fuente","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Granada, Av. Ilustraci\u00f3n 60, 18016 Granada, Spain"},{"name":"Brain, Mind and Behaviour Research Center (CIMCYC), University of Granada, Campus Universitario de Cartuja s\/n, 18011 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5310-9638","authenticated-orcid":false,"given":"Jos\u00e9 Luis","family":"Romero-B\u00e9jar","sequence":"additional","affiliation":[{"name":"Institute for Biosanitary Research (ibs.GRANADA), 18012 Granada, Spain"},{"name":"Department of Statistics and Operations Research, University of Granada, Av. de Fuente Nueva, s\/n, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Membrive-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Institute for Biosanitary Research (ibs.GRANADA), 18012 Granada, Spain"},{"name":"Ceuta Faculty of Health Sciences, University of Granada, Cortadura del Valle s\/n, 51001 Ceuta, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,15]]},"reference":[{"key":"ref_1","first-page":"3649","article-title":"Delirium en los pacientes mayores","volume":"13","author":"Espeso","year":"2022","journal-title":"Med.-Programa Form. 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Physicians Open"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"}],"container-title":["Brain Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-3425\/16\/8\/864\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:06:08Z","timestamp":1786975568000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-3425\/16\/8\/864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,15]]},"references-count":52,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["brainsci16080864"],"URL":"https:\/\/doi.org\/10.3390\/brainsci16080864","relation":{},"ISSN":["2076-3425"],"issn-type":[{"value":"2076-3425","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,15]]}}}