{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:48:20Z","timestamp":1760240900467,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T00:00:00Z","timestamp":1571270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain Sciences"],"abstract":"<jats:p>We report the case of a male multiple sclerosis (MS) patient with type 2 diabetes (T2D), asthma, major depression (MD or major depressive disorder, MDD), and other chronic conditions, after his recent difficulties with craniopharyngioma and cranial nerve-VI (CN6) palsy. In addition, we show magnetic resonance image and spectroscopy (MRI, MRS), Humphrey\u2019s Visual Field (HVF), and retinal nerve fiber layer thickness (RNFLT) findings to explain the changes in the patient\u2019s health, and discuss the methods that helped\/help him sustain productivity and euthymia despite long-standing problems and new CNS changes.<\/jats:p>","DOI":"10.3390\/brainsci9100281","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T04:12:59Z","timestamp":1571371979000},"page":"281","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Post-Craniopharyngioma and Cranial Nerve-VI Palsy Update on a MS Patient with Major Depression and Concurrent Neuroimmune Conditions"],"prefix":"10.3390","volume":"9","author":[{"given":"Navzer D.","family":"Sachinvala","sequence":"first","affiliation":[{"name":"United States Department of Agriculture, Agricultural Research Service, USDA-ARS, New Orleans, Home 2261 Brighton Place, Harvey, LA 70058, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angeline","family":"Stergiou","sequence":"additional","affiliation":[{"name":"Department of Medicine, Fairfield Medical Center, 401 North Ewing, Lancaster, OH 43130, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duane E.","family":"Haines","sequence":"additional","affiliation":[{"name":"Department of Neurobiology and Anatomy, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157, USA"},{"name":"Department of Neurology, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC 27157, USA"},{"name":"Department of Neurobiology and Anatomy, The University of Mississippi Medical Center, Jackson, MS 39216, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armen","family":"Kocharian","sequence":"additional","affiliation":[{"name":"Department of Radiology, Houston Methodist Hospital, 6565 Fannin Street, Houston, TX 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Lawton","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ochsner Hospital, 1514 Jefferson Highway, New Orleans, 70121, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,10,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.2147\/NDT.S169292","article-title":"Remitting long-standing major depression in a multiple sclerosis patient with several concurrent conditions","volume":"14","author":"Sachinvala","year":"2018","journal-title":"Neuropsychiatr. 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