{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T16:07:19Z","timestamp":1785859639808,"version":"3.56.0"},"reference-count":34,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T00:00:00Z","timestamp":1621382400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>Objective: To evaluate the odds of association between suicidal ideation and\/or attempt with comorbid eating disorders in adolescents with major depressive disorder (MDD). Methods: We conducted a cross-sectional study and included 122,020 adolescents with a primary diagnosis of MDD from the nationwide inpatient sample (NIS, 2012\u20132014). They were sub-grouped by a comorbid diagnosis of eating disorders (N = 1675). We calculated the adjusted odds ratio (aOR) using a logistic regression model with demographic confounders for associations of eating disorders with suicidal ideation and attempt. Results: Suicidal ideations were seen in a higher proportion of adolescents with eating disorders (46.3% vs. 14.2% in those without eating disorders). On the contrary, a low proportion of adolescents with eating disorders had suicidal attempts (0.9% vs. 39.4% in those without eating disorders). Overall, eating disorders were associated with higher odds for suicidal ideations (aOR 5.36, 95% CI 4.82\u20135.97) compared to those without eating disorders, but with lower odds of suicidal attempt (aOR 0.02, 95% CI 0.01\u20130.03). Conclusions: Adolescents with MDD and comorbid eating disorders had five-times increased odds of suicidal ideations but lower odds of a suicide attempt. Self-harm\/injurious behaviors are early signs of suicidal ideations in these patients. A collaborative care model is required for the screening, early diagnosis, and management of adolescents with eating disorders to improve their quality of life.<\/jats:p>","DOI":"10.3390\/bs11050078","type":"journal-article","created":{"date-parts":[[2021,5,19]],"date-time":"2021-05-19T12:58:07Z","timestamp":1621429087000},"page":"78","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2895-9155","authenticated-orcid":false,"given":"Rikinkumar S.","family":"Patel","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Griffin Memorial Hospital, Norman, OK 73071, USA"},{"name":"Department of Psychiatry and Behavioral Sciences, Oklahoma State University, Tulsa, OK 74106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"Machado","sequence":"additional","affiliation":[{"name":"Father Muller Medical College, Mangalore 575002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William E.","family":"Tankersley","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Griffin Memorial Hospital, Norman, OK 73071, USA"},{"name":"Department of Psychiatry and Behavioral Sciences, Oklahoma State University, Tulsa, OK 74106, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e20160436","DOI":"10.1542\/peds.2016-0436","article-title":"Suicide in Elementary School-Aged Children and Early Adolescents","volume":"138","author":"Sheftall","year":"2016","journal-title":"Pediatrics"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e20161420","DOI":"10.1542\/peds.2016-1420","article-title":"Committee on Adolescence Suicide and Suicide Attempts in Adolescents","volume":"138","author":"Shain","year":"2016","journal-title":"Pediatrics"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1001\/archgenpsychiatry.2011.22","article-title":"Prevalence and correlates of eating disorders in adolescents. 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