{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T09:12:48Z","timestamp":1772183568714,"version":"3.50.1"},"reference-count":38,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Blythedale Children\u2019s Hospital","award":["NIH R01 HD076436"],"award-info":[{"award-number":["NIH R01 HD076436"]}]},{"name":"Blythedale Children\u2019s Hospital","award":["NIH K08 NS073796"],"award-info":[{"award-number":["NIH K08 NS073796"]}]},{"name":"Thomas and Agnes Carvel Foundation","award":["NIH R01 HD076436"],"award-info":[{"award-number":["NIH R01 HD076436"]}]},{"name":"Thomas and Agnes Carvel Foundation","award":["NIH K08 NS073796"],"award-info":[{"award-number":["NIH K08 NS073796"]}]},{"name":"National Institutes of Health","award":["NIH R01 HD076436"],"award-info":[{"award-number":["NIH R01 HD076436"]}]},{"name":"National Institutes of Health","award":["NIH K08 NS073796"],"award-info":[{"award-number":["NIH K08 NS073796"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>Constraint-induced movement therapy (CIMT) and bimanual therapy (BT) are among the most effective hand therapies for children with unilateral cerebral palsy (uCP). Since they train different aspects of hand use, they likely have synergistic effects. The aim of this study was to examine the efficacy of different combinations of mCIMT and BT in an intensive occupational therapy program for children with uCP. Children (n = 35) participated in intensive modified CIMT (mCIMT) and BT, 6 weeks, 5 days\/week, 6 h\/day. During the first 2 weeks, children wore a mitt over the less-affected hand and engaged in functional and play activities with the affected hand. Starting in week 3, bimanual play and functional activities were added progressively, 1 hour\/week. This intervention was compared to two different schedules of block interventions: (1) 3 weeks of mCIMT followed by 3 weeks of BT, and (2) 3 weeks of BT followed by 3 weeks of mCIMT. Hand function was tested before, after, and two months after therapy with the Assisting Hand Assessment (AHA), Pediatric Evaluation of Disability Inventory (PEDI), and Canadian Occupational Performance Measure (COPM). All three groups of children improved in functional independence (PEDI; p &lt; 0.031), goal performance (COPM Performance; p &lt; 0.0001) and satisfaction (COPM Satisfaction; p &lt; 0.0001), which persisted two months post-intervention. All groups showed similar amounts of improvement, indicating that the delivery schedule for mCIMT and BT does not significantly impact the outcomes.<\/jats:p>","DOI":"10.3390\/bs13060490","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T10:52:15Z","timestamp":1686307935000},"page":"490","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Combining Unimanual and Bimanual Therapies for Children with Hemiparesis: Is There an Optimal Delivery Schedule?"],"prefix":"10.3390","volume":"13","author":[{"given":"Ka Lai K.","family":"Au","sequence":"first","affiliation":[{"name":"Blythedale Children\u2019s Hospital, Valhalla, NY 10595, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie L.","family":"Knitter","sequence":"additional","affiliation":[{"name":"Blythedale Children\u2019s Hospital, Valhalla, NY 10595, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Morrow-McGinty","sequence":"additional","affiliation":[{"name":"Blythedale Children\u2019s Hospital, Valhalla, NY 10595, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talita C.","family":"Campos","sequence":"additional","affiliation":[{"name":"School of Nursing, Columbia University Irving Medical Center, New York, NY 10032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason B.","family":"Carmel","sequence":"additional","affiliation":[{"name":"Weinberg Family Cerebral Palsy Center, Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9538-9228","authenticated-orcid":false,"given":"Kathleen M.","family":"Friel","sequence":"additional","affiliation":[{"name":"Burke Neurological Institute, White Plains, NY 10605, USA"},{"name":"Brain Mind Research Institute, Weill Cornell Medical College, New York, NY 10021, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s11910-020-1022-z","article-title":"State of the Evidence Traffic Lights 2019: Systematic Review of Interventions for Preventing and Treating Children with Cerebral Palsy","volume":"20","author":"Novak","year":"2020","journal-title":"Curr. 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