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Development Program","award":["2021C03107"],"award-info":[{"award-number":["2021C03107"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>Individuals with bipolar disorder (BD) have a greater suicide risk than the general population. In this study, we employed latent profile analysis (LPA) to explore whether Chinese individuals with different phases of BD differed at the levels of suicidal ideation. We recruited 517 patients. Depressive symptoms were measured using the 24-item Hamilton Depression Rating Scale (HAMD-24), and manic symptoms were evaluated using the Young Mania Rating Scale (YMRS). The extent of suicidal thoughts was determined through the Beck Scale for Suicide Ideation (BSSI). The scores of HAMD and YMRS were used to perform LPA. LPA categorized participants into three classes: one exhibiting severe depressive and mild manic symptomatology, another showing severe depressive and severe manic symptomatology, and the third one displaying severe depressive and intermediate manic symptomatology. Suicidal ideation levels were found to be remarkably elevated across all three classes. Additionally, the three classes showed no significant differences in terms of suicidal ideation. Our research confirms the link between depressive symptoms and suicide, independent of the manic symptoms. These findings carry meaning as they provide insight into the suicide risk profiles within different phases of BD.<\/jats:p>","DOI":"10.3390\/bs14050360","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T05:26:13Z","timestamp":1714022773000},"page":"360","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Latent Profile Analysis of Suicidal Ideation in Chinese Individuals with Bipolar Disorder"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4904-471X","authenticated-orcid":false,"given":"Yanmeng","family":"Pan","sequence":"first","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4702-4216","authenticated-orcid":false,"given":"Huaizhi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"},{"name":"School of Psychiatry, Wenzhou Medical University, Wenzhou 325035, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yimeng","family":"Geng","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0570-670X","authenticated-orcid":false,"given":"Shaohua","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China"},{"name":"Nanhu Brain-Computer Interface Institute, Hangzhou 310003, China"},{"name":"Zhejiang Key Laboratory of Precision Psychiatry, Hangzhou 310003, China"},{"name":"Brain Research Institute, Zhejiang University, Hangzhou 310003, China"},{"name":"Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou 310003, China"},{"name":"MOE Frontier Science Center for Brain Science and Brain-machine Integration, Zhejiang University, Hangzhou 310003, China"},{"name":"Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1192\/bjp.2022.19","article-title":"Life expectancy and years of potential life lost in bipolar disorder: Systematic review and meta-analysis","volume":"221","author":"Chan","year":"2022","journal-title":"Br. 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