{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:58:09Z","timestamp":1777564689707,"version":"3.51.4"},"reference-count":45,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T00:00:00Z","timestamp":1729036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>Background: In the literature, female anorgasmia (AO) is closely related to obsessive\u2013compulsive disorder (OCD), but no publication has explored the role of individual obsessive traits that may also be typical of other disorders, assuming that repetitive thoughts and compulsions must necessarily correspond to an obsessive-type neurotic profile. It is worth investigating and assessing the specific weight of other morbid conditions involved, beyond OCD. Materials and Methods: This study was conducted during 2022\u20132023 by selecting 208 Italian clinical patients from private databases. They submitted to individual clinical interviews and two psychometric questionnaires (Perrotta Integrative Clinical Interviews 3, PICI-3-TA, and Perrotta Individual Sexual Matrix Questionnaire, PSM-Q). Results: Among the 208 patients (M: 39.05 years), divided into subgroups by age and obsessive symptomatology, no significant differences were found between the subgroups in the comparisons of the data obtained from the administration of the PSM-Q. Conclusions: This study confirms that it is not OCD that correlates with OA but obsessive traits, which are also common to other psychopathological disorders, such as bipolar disorder, borderline disorder, manic, and psychotic disorders and, therefore, in psychotherapy, it is necessary to intervene with a clinical approach that has in mind the patient\u2019s psychopathological personality picture and the causes that originated or reinforced OA.<\/jats:p>","DOI":"10.3390\/bs14100953","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T04:42:15Z","timestamp":1729140135000},"page":"953","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Secondary Female Anorgasmia in Patients with Obsessive Traits: A Study"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0229-5562","authenticated-orcid":false,"given":"Giulio","family":"Perrotta","sequence":"first","affiliation":[{"name":"Istituto per lo Studio delle Psicoterapie (ISP), 00185 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8416-2845","authenticated-orcid":false,"given":"Stefano","family":"Eleuteri","sequence":"additional","affiliation":[{"name":"Department of Developmental Psychology, Sapienza University Rome, 00166 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,10,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/S1701-2163(16)35341-5","article-title":"Female sexual health consensus clinical guidelines","volume":"34","author":"Lamont","year":"2012","journal-title":"J. Obstet. Gynaecol. Can."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.sxmr.2020.07.007","article-title":"Psychological and Behavioral Treatment of Female Orgasmic Disorder","volume":"9","author":"Marchand","year":"2021","journal-title":"Sex Med. Rev."},{"key":"ref_3","first-page":"9864","article-title":"Cultural anorgasmia: Considerations in the evaluation of male infertility in the Hasidic community","volume":"26","author":"Dubowitch","year":"2019","journal-title":"Can. J. Urol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association (APA) (2022). Diagnostic and Statistical Manual of Mental Disorders, APA. [5th ed.].","DOI":"10.1176\/appi.books.9780890425787"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1016\/j.fertnstert.2015.09.029","article-title":"Delayed orgasm and anorgasmia","volume":"104","author":"Jenkins","year":"2015","journal-title":"Fertil. Steril."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.21037\/tau.2016.05.10","article-title":"Epidemiology of delayed ejaculation","volume":"5","author":"Mollaioli","year":"2016","journal-title":"Transl. Androl. Urol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1071\/SH06005","article-title":"A general look at female orgasm and anorgasmia","volume":"3","author":"Redelman","year":"2006","journal-title":"Sex Health"},{"key":"ref_8","unstructured":"Litner, J. (2019). Encyclopedia of Couple and Family Therapy, Springer."},{"key":"ref_9","unstructured":"Kaplan, H.S. (1987). The Illustrated Manual of Sex Therapy, Brunner\/Mazel Press."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1111\/j.1743-6109.2010.01928.x","article-title":"Disorders of Orgasm in Women: A Literature Review of Etiology and Current Treatments","volume":"7","author":"IsHak","year":"2010","journal-title":"J. Sex Med."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1743-6109.2007.00630.x","article-title":"Persistent Sexual Dysfunction after Discontinuation of Selective Serotonin Reuptake Inhibitors","volume":"5","author":"Csoka","year":"2008","journal-title":"J. Sex. Med."},{"key":"ref_12","unstructured":"Simonelli, C., Fabrizi, A., and Rossi, R. (2019). Sessuologia Clinica, Franco Angeli."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1192\/bjo.2018.35","article-title":"Alprazolam-induced dose-dependent anorgasmia: Case analysis","volume":"4","author":"Kaufman","year":"2018","journal-title":"BJPsych Open"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1176\/ajp.146.6.804","article-title":"Fluoxetine and anorgasmia","volume":"146","author":"Kline","year":"1989","journal-title":"Am. J. Psychiatry"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1176\/ajp.144.4.527a","article-title":"Anorgasmia caused by an MAOI","volume":"144","author":"Jacobson","year":"1987","journal-title":"Am. J. Psychiatry"},{"key":"ref_16","first-page":"32","article-title":"Treatment of clomipramine-induced anorgasmia with yohimbine: A case report","volume":"51","author":"Price","year":"1990","journal-title":"J. Clin. Psychiatry"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1176\/ajp.153.10.1365a","article-title":"Treatment of fluvoxamine-induced anorgasmia with a partial drug holiday","volume":"153","author":"Treuer","year":"1996","journal-title":"Am. J. Psychiatry"},{"key":"ref_18","first-page":"347","article-title":"The serotonin antagonist mianserin for treatment of serotonin reuptake inhibitor-induced sexual dysfunction in women: An open-label add-on study","volume":"22","author":"Aizenberg","year":"1999","journal-title":"Clin. Neuropharmacol."},{"key":"ref_19","unstructured":"Giustozzi, A.A. (2009). Sexual dysfunction in women. Ferri FF. Ferri\u2019s Clinical Advisor 2010, Mosby."},{"key":"ref_20","first-page":"42","article-title":"Anxiety disorders: Definitions, contexts, neural correlates and strategic therapy","volume":"6","author":"Perrotta","year":"2019","journal-title":"J. Neur. Neurosci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1176\/ps.50.8.1076","article-title":"Sildenafil for Women Patients with Antidepressant-Induced Sexual Dysfunction","volume":"50","year":"1999","journal-title":"Psychiatr. Serv."},{"key":"ref_22","first-page":"1","article-title":"Panic Disorder: Definitions, Contexts, Neural Correlates and Clinical Strategies","volume":"1","author":"Perrotta","year":"2019","journal-title":"Curr. Tr. Clin. Med. Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.17352\/2455-5460.000038","article-title":"Depressive disorders: Definitions, contexts, differential diagnosis, neural correlates and clinical strategies","volume":"5","author":"Perrotta","year":"2019","journal-title":"Arch. Depress. Anxiety"},{"key":"ref_24","first-page":"8","article-title":"Obsessive-Compulsive Disorder: Definition, contexts, neural correlates and clinical strategies","volume":"1","author":"Perrotta","year":"2019","journal-title":"J. Neurol."},{"key":"ref_25","first-page":"CRPBD-100006","article-title":"Psychological trauma: Definition, clinical contexts, neural correlations and therapeutic approaches","volume":"2019","author":"Perrotta","year":"2020","journal-title":"Curr. Res. Psychiatry Brain Disord."},{"key":"ref_26","first-page":"e34719","article-title":"Improvement of Anorgasmia and Anejaculation After Spinal Manipulation in an Older Man With Lumbar Stenosis: A Case Report","volume":"15","author":"Trager","year":"2023","journal-title":"Cureus"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0166-4328(99)00086-8","article-title":"Hormone-neurotransmitter interactions in the control of sexual behavior","volume":"105","author":"Hull","year":"1999","journal-title":"Behav. Brain Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"20267","DOI":"10.1073\/pnas.1910295116","article-title":"An experimental test of the ovulatory homolog model of female orgasm","volume":"116","author":"Pavlicev","year":"2019","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.36740\/WLek201910125","article-title":"Sexual problems in the patients with psychiatric disorders","volume":"72","author":"Piontek","year":"2019","journal-title":"Wiad Lek"},{"key":"ref_30","first-page":"381","article-title":"Sexual dysfunction in obsessive compulsive disorder and panic disorder","volume":"24","author":"Aksoy","year":"2012","journal-title":"Psychiatr. Danub."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1525-1403.2006.00040.x","article-title":"Neurally augmented sexual function in human females: A preliminary investigation","volume":"9","author":"Meloy","year":"2006","journal-title":"Neuromodulation"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.jsxm.2019.05.007","article-title":"Functional Magnetic Resonance Imaging Detects Between-Group Differences in Neural Activation Among Men with Delayed Orgasm Compared with Normal Controls: Preliminary Report","volume":"16","author":"Flannigan","year":"2019","journal-title":"J. Sex Med."},{"key":"ref_33","first-page":"255","article-title":"Sexual dysfunction in relapsing-remitting multiple sclerosis: Magnetic resonance imaging, clinical, and psychological correlates","volume":"21","author":"Barak","year":"1996","journal-title":"J. Psychiatry Neurosci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1080\/10532528.2004.10559820","article-title":"Women\u2019s orgasm","volume":"15","author":"Meston","year":"2004","journal-title":"Annu. Rev. Sex Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1016\/j.jsxm.2017.08.014","article-title":"Brain Activity Unique to Orgasm in Women: An fMRI Analysis","volume":"14","author":"Wise","year":"2017","journal-title":"J. Sex Med."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.neuron.2019.01.046","article-title":"Obsessive-Compulsive Disorder: Puzzles and Prospects","volume":"102","author":"Robbins","year":"2019","journal-title":"Neuron"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/pcn.12195","article-title":"Neurobiological model of obsessive-compulsive disorder: Evidence from recent neuropsychological and neuroimaging findings","volume":"68","author":"Nakao","year":"2014","journal-title":"Psychiatry Clin. Neurosci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41386-021-01130-2","article-title":"The prefrontal cortex and OCD","volume":"47","author":"Ahmari","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"ref_39","first-page":"1186","article-title":"Developmental neuroimaging studies of OCD: The maturation of a field","volume":"49","author":"Rauch","year":"2010","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"022","DOI":"10.17352\/ojt.000043","article-title":"The \u201cHuman Emotions\u201d and the new \u201cPerrotta Human Emotions Model\u201d (PHEM-2): Structural and functional updates to the first model","volume":"7","author":"Basiletti","year":"2023","journal-title":"Open J. Trauma"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/ibra.12148","article-title":"Perrotta Integrative Clinical Interviews 3 (PICI-3): Development, regulation, updation, and validation of the psychometric instrument for the identification of functional and dysfunctional personality traits and diagnosis of psychopathological disorders, for children (8\u201310 years), preadolescents (11\u201313 years), adolescents (14\u201318 years), adults (19\u201369 years), and elders (70\u201390 years)","volume":"10","author":"Perrotta","year":"2024","journal-title":"Ibrain"},{"key":"ref_43","first-page":"062","article-title":"\u201cPerrotta Individual Sexual Matrix Questionnaire\u201d (PSM-Q): Technical updates and clinical research","volume":"4","author":"Perrotta","year":"2021","journal-title":"Int. J. Sex Reprod. Health Care"},{"key":"ref_44","first-page":"1","article-title":"The strategic clinical model in psychotherapy: Theoretical and practical profiles","volume":"3","author":"Perrotta","year":"2020","journal-title":"J. Addict. Adolesc. Behav."},{"key":"ref_45","unstructured":"Espugnatore, G., Fabiano, G., Gentili, S., Perrotta, G., Pillon, P., and Zaffino, A. (2023). La Psicoterapia Strategica Nella Pratica Clinica, Primiceri Editore."}],"container-title":["Behavioral Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-328X\/14\/10\/953\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:14:04Z","timestamp":1760112844000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-328X\/14\/10\/953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,16]]},"references-count":45,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2024,10]]}},"alternative-id":["bs14100953"],"URL":"https:\/\/doi.org\/10.3390\/bs14100953","relation":{},"ISSN":["2076-328X"],"issn-type":[{"value":"2076-328X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,16]]}}}