{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:12:54Z","timestamp":1790611974476,"version":"4.1.0"},"reference-count":97,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T00:00:00Z","timestamp":1738886400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Progetto Ateneo Grande 2021 of \u201cSapienza\u201d University of Rome","award":["RG12117A8838F686"],"award-info":[{"award-number":["RG12117A8838F686"]}]},{"name":"Progetto Ateneo Grande 2021 of \u201cSapienza\u201d University of Rome","award":["CUP MASTER B53D23014300006"],"award-info":[{"award-number":["CUP MASTER B53D23014300006"]}]},{"name":"PRIN 2022","award":["RG12117A8838F686"],"award-info":[{"award-number":["RG12117A8838F686"]}]},{"name":"PRIN 2022","award":["CUP MASTER B53D23014300006"],"award-info":[{"award-number":["CUP MASTER B53D23014300006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>The perinatal period, due to the many physical, psychological, and social changes in future mothers, may represent a critical phase with an increased risk for mental health. Postpartum depression (PPD) is one of the main syndromes that affect around 17 percent of women after pregnancy and in the first months of motherhood. This systematic review, following PRISMA guidelines, aimed to identify the main pre-partum psychiatric risk factors that may influence the occurrence and diagnosis of PPD with a focus on the antenatal and clinical history of depression, bipolar disorders, obsessive\u2013compulsive disorder, and psychosis. From the search in main scientific databases (Web of Science, Pubmed, Psychinfo, and Scopus), 37 articles were included for the critical evaluation. The studies showed that antenatal depression and depressive episodes during pregnancy represent higher risk factors for PPD. Also, a clinical history of major depression, especially if associated with other risk factors (such as poor demographic or social conditions) increases the risk for PPD. From the systematic analysis emerged a paucity of studies considering the other psychiatric syndromes that should be overcome. PPD represents a multisystemic syndrome involving all the aspects of a mother\u2019s life as well as affecting children\u2019s development; for this reason, exploring the role of mental health risk factors for PPD onset, progression, and prognosis is relevant, from a clinical point of view, to find the best way to promote the mother\u2019s psychological well-being from the antenatal period.<\/jats:p>","DOI":"10.3390\/bs15020173","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T04:00:28Z","timestamp":1738900828000},"page":"173","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Psychiatric Risk Factors for Postpartum Depression: A Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"given":"Renata","family":"Tambelli","sequence":"first","affiliation":[{"name":"Department of Dynamic and Clinical Psychology and Health Studies, Via degli Apuli 1, 00185 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Tosto","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology and Health Studies, Via degli Apuli 1, 00185 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6696-5855","authenticated-orcid":false,"given":"Francesca","family":"Favieri","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology and Health Studies, Via degli Apuli 1, 00185 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1111\/jog.12471","article-title":"Predictors and incidence of post-partum depression: A longitudinal cohort study","volume":"40","author":"Abdollahi","year":"2014","journal-title":"Journal of Obstetrics and Gynaecology Research"},{"key":"ref_2","first-page":"e30898","article-title":"Risk factors of postpartum depression","volume":"14","author":"Agrawal","year":"2022","journal-title":"Cureus"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.jad.2021.04.046","article-title":"Prevalence and predictors of postpartum depression in Upper Egypt: A multicenter primary health care study","volume":"290","author":"Ahmed","year":"2021","journal-title":"Journal of Affective Disorders"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1017\/S0033291721005559","article-title":"Can epigenetics shine a light on the biological pathways underlying major mental disorders?","volume":"52","author":"Alameda","year":"2022","journal-title":"Psychological Medicine"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/da.22290","article-title":"The association between sociodemographic characteristics and postpartum depression symptoms among Arab-Bedouin women in Southern Israel","volume":"32","author":"Zeadna","year":"2015","journal-title":"Depression and Anxiety"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1111\/jmwh.12617","article-title":"Risk for postpartum depression among immigrant arabic women in the united states: A feasibility study","volume":"62","author":"Alhasanat","year":"2017","journal-title":"Journal of Midwifery & Women\u2019s Health"},{"key":"ref_7","first-page":"e14603","article-title":"Prevalence of postpartum depression and associated risk factors among women in Jeddah, Western Saudi Arabia","volume":"13","author":"Alsayed","year":"2021","journal-title":"Cureus"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"E35","DOI":"10.1017\/sjp.2019.33","article-title":"Risk factors for postnatal depression among primipara mothers","volume":"22","author":"Alzahrani","year":"2019","journal-title":"The Spanish Journal of Psychology"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"APA (American Psychiatric Association) (2013). 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