{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T10:16:56Z","timestamp":1791454616229,"version":"4.3.3"},"reference-count":83,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>A range of factors affect performance on tasks associated with creativity, including stress, pharmacology, behavioral interventions, and neural stimulation strategies. Most of the pharmacological impacts have focused on the dopaminergic and noradrenergic systems. However, some evidence suggests that these systems may differ in their impact on performance on divergent and convergent tasks. We performed a systematic PubMed review examining the results for \u2018creativity and (dopamine or dopaminergic)\u2019 and \u2018creativity and (norepinephrine or noradrenergic or adrenergic)\u2019. The dopaminergic search yielded 238 articles. The noradrenergic search yielded 102 articles. The articles were screened for actually targeting these systems (for example, by pharmacological intervention or by examining genetics relevant to these systems) and examining performance on divergent or convergent tasks. Results of the review of the qualifying articles lent some support to an impact of the dopaminergic system on divergent task performance, and suggested an impact of the noradrenergic system on convergent task performance, but often required additional factors such as stress to reveal robust effects. This review suggests a differential impact of the dopaminergic system and noradrenergic system on divergent and convergent task performance, but studies to systematically address this question across conditions are lacking, and would be needed going forward.<\/jats:p>","DOI":"10.3390\/bs15091185","type":"journal-article","created":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T08:28:15Z","timestamp":1756715295000},"page":"1185","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dopaminergic and Noradrenergic Contributions to Divergent and Convergent Creativity Task Performance, a Systematic Review"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0298-0634","authenticated-orcid":false,"given":"David Q.","family":"Beversdorf","sequence":"first","affiliation":[{"name":"Department of Neurology, Radiology, and Psychological Science, William and Nancy Thompson Endowed Chair in Radiology, University of Missouri, Columbia, MO 65211, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,30]]},"reference":[{"key":"ref_1","first-page":"4946","article-title":"The \u201ccreative right brain\u201d revisited: Individual creativity and associative priming in the right hemisphere relate to hemispheric asymmetries in reward brain function","volume":"27","author":"Aberg","year":"2017","journal-title":"Cerebral Cortex"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00426-022-01658-y","article-title":"Dopamine supports idea originality: The role of spontaneous eye blink rate on divergent thinking","volume":"87","author":"Agnoli","year":"2023","journal-title":"Psychological Research"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"eabe9681","DOI":"10.1126\/science.abe9681","article-title":"A cell type-specific cortico-subcortical brain circuit for investigatory and novelty-seeking behavior","volume":"372","author":"Ahmadlou","year":"2021","journal-title":"Science"},{"key":"ref_4","first-page":"468","article-title":"Noradrenergic modulation of cognitive flexibility during stress","volume":"19","author":"Alexander","year":"2007","journal-title":"Frontiers in Human Neuroscience"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.31887\/DCNS.2008.10.2\/ncandreasen","article-title":"The relationship between creativity and mood disorders","volume":"10","author":"Andreasen","year":"2008","journal-title":"Dialogues in Clinical Neuroscience"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1016\/j.cub.2018.03.069","article-title":"Dopamine modulates option generation for behavior","volume":"28","author":"Ang","year":"2018","journal-title":"Current Biology"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Appling, C., Nuraini, N., Hart, E., Wang, D., Tosh, A., Beversdorf, D., and Ferguson, B. 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