{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T07:59:15Z","timestamp":1781164755623,"version":"3.54.1"},"reference-count":60,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Neuromotor Research Clinic at the Fralin Biomedical Research Institute at Virginia Tech Carilion"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioral Sciences"],"abstract":"<jats:p>Children with developmental disabilities are less physically active and at increased risk for chronic conditions that physical activity might ameliorate. This study examined the relationships between the impact of physical activity (e.g., muscles burning, body tiredness), physical activity time and fatigue in children with Cerebral Palsy (CP) and Down Syndrome (DS) in comparison to typically developing (TD) children. A convenience sample of children and parents was enrolled. All children were between 4 and 10 years, ambulatory, medically stable, not taking sleep-aid medications and were either TD (n = 20) or diagnosed with CP (n = 14) or DS (n = 5). Children and parents separately answered questionnaires about participation in physical activity and fatigue during the past week, yielding retrospective data. Additionally, they completed prospective questionnaires for 3 consecutive days. Repeated measures multivariate and univariate analyses (post hoc) of variance, along with correlations between variables were completed. Analyses of retrospective data yielded no specific findings. Prospectively, all groups of parents reported that as the impact of physical activity increased, perceptions of fatigue decreased (r = \u22120.349; p &lt; 0.001). Parents of children with Cerebral Palsy noted a negative relationship between the time spent doing physical activity and perceptions of fatigue (r = \u22120.553; p &lt; 0.001). Between-group differences in perceptions of fatigue occurred for children with CP compared to TD (F = 8.248; p &lt; 0.001). Parent-reported findings suggest potential associations between physical activity participation and perceptions of fatigue across diagnostic groups.<\/jats:p>","DOI":"10.3390\/bs16060945","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T06:57:17Z","timestamp":1781161037000},"page":"945","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Understanding Physical Activity Demands and Reported Perceptions of Fatigue in Children with Developmental Disabilities"],"prefix":"10.3390","volume":"16","author":[{"given":"Kavya","family":"Iyer","sequence":"first","affiliation":[{"name":"Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA 24060, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Stevenson","sequence":"additional","affiliation":[{"name":"Department of Developmental and Behavioral Pediatrics, University of Virginia, Charlottesville, VA 22908, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vydia","family":"Permashwar","sequence":"additional","affiliation":[{"name":"Department of General Pediatrics, Carilion Clinic, Roanoke, VA 24018, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Howell","sequence":"additional","affiliation":[{"name":"Department of Human Development and Family Science, Virginia Tech, Blacksburg, VA 24060, USA"},{"name":"Neuromotor Research Clinic, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA 24016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7366-7477","authenticated-orcid":false,"given":"Stephanie","family":"DeLuca","sequence":"additional","affiliation":[{"name":"Neuromotor Research Clinic, Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA 24016, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Aljuhani, O., Alharbi, S., Hakami, R., Alsaeedi, D., Alqadheb, W., Al-Sadaawi, N., and Alosaimi, F. 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