{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:08:28Z","timestamp":1790320108519,"version":"4.1.0"},"reference-count":90,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Macy Easom Cancer Research Foundation Grant","award":["S.V."],"award-info":[{"award-number":["S.V."]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Hepatoblastoma is the most common childhood liver malignancy. The management of hepatoblastoma requires multidisciplinary efforts. The five-year overall survival is approximately 80% in developed countries. Surgery remains the mainstay of treatment for hepatoblastoma, and meticulous techniques must be employed to ensure safe and effective local control surgeries. Additionally, there have been several advances from both pediatric and adult literature in the way liver tumor surgery is performed. In this review, we highlight important aspects of liver surgery for hepatoblastoma, the management of metastatic disease, and the most current technical advances in performing these procedures in a safe and effective manner.<\/jats:p>","DOI":"10.3390\/cancers11121944","type":"journal-article","created":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T03:16:36Z","timestamp":1575515796000},"page":"1944","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Surgical Management of Hepatoblastoma and Recent Advances"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9140-3806","authenticated-orcid":false,"given":"Tianyou","family":"Yang","sequence":"first","affiliation":[{"name":"Divisions of Pediatric Surgery and Surgical Research, Michael E. DeBakey Department of Surgery, Pediatric Surgical Oncology Laboratory, Texas Children\u2019s Surgical Oncology Program, Texas Children\u2019s Liver Tumor Program, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA"},{"name":"Department of Pediatric Surgery, Guangzhou Women and Children\u2019s Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Whitlock","sequence":"additional","affiliation":[{"name":"Divisions of Pediatric Surgery and Surgical Research, Michael E. DeBakey Department of Surgery, Pediatric Surgical Oncology Laboratory, Texas Children\u2019s Surgical Oncology Program, Texas Children\u2019s Liver Tumor Program, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev A.","family":"Vasudevan","sequence":"additional","affiliation":[{"name":"Divisions of Pediatric Surgery and Surgical Research, Michael E. DeBakey Department of Surgery, Pediatric Surgical Oncology Laboratory, Texas Children\u2019s Surgical Oncology Program, Texas Children\u2019s Liver Tumor Program, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1053\/jhep.2003.50375","article-title":"Epidemiology of primary hepatic malignancies in U.S. children","volume":"38","author":"Darbari","year":"2003","journal-title":"Hepatology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1111\/hpb.12112","article-title":"Predictors of survival and incidence of hepatoblastoma in the paediatric population","volume":"15","author":"Allan","year":"2013","journal-title":"HPB"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/cncr.23169","article-title":"Trends in childhood cancer incidence in the U.S. (1992\u20132004)","volume":"112","author":"Linabery","year":"2008","journal-title":"Cancer"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.jcma.2017.11.012","article-title":"Hepatoblastoma incidence in Taiwan: A population-based study","volume":"81","author":"Hung","year":"2018","journal-title":"J. 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