{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:43:35Z","timestamp":1787240615326,"version":"build-2736575974"},"reference-count":21,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T00:00:00Z","timestamp":1580688000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013197","name":"Canada's Michael Smith Genome Sciences Centre","doi-asserted-by":"publisher","award":["ID5892"],"award-info":[{"award-number":["ID5892"]}],"id":[{"id":"10.13039\/100013197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MC2-139146"],"award-info":[{"award-number":["MC2-139146"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>New streamlined models for genetic counseling and genetic testing have recently been developed in response to increasing demand for cancer genetic services. To improve access and decrease wait times, we implemented an oncology clinic-based genetic testing model for breast and ovarian cancer patients in a publicly funded population-based health care setting in British Columbia, Canada. This observational study evaluated the oncology clinic-based model as compared to a traditional one-on-one approach with a genetic counsellor using a multi-gene panel testing approach. The primary objectives were to evaluate wait times and patient reported outcome measures between the oncology clinic-based and traditional genetic counselling models. Secondary objectives were to describe oncologist and genetic counsellor acceptability and experience. Wait times from referral to return of genetic testing results were assessed for 400 patients with breast and\/or ovarian cancer undergoing genetic testing for hereditary breast and ovarian cancer from June 2015 to August 2017. Patient wait times from referral to return of results were significantly shorter with the oncology clinic-based model as compared to the traditional model (403 vs. 191 days; p &lt; 0.001). A subset of 148 patients (traditional n = 99; oncology clinic-based n = 49) completed study surveys to assess uncertainty, distress, and patient experience. Responses were similar between both models. Healthcare providers survey responses indicated they believed the oncology clinic-based model was acceptable and a positive experience. Oncology clinic-based genetic testing using a multi-gene panel approach and post-test counselling with a genetic counsellor significantly reduced wait times and is acceptable for patients and health care providers.<\/jats:p>","DOI":"10.3390\/cancers12020338","type":"journal-article","created":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T02:59:18Z","timestamp":1580957958000},"page":"338","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Oncology Clinic-Based Hereditary Cancer Genetic Testing in a Population-Based Health Care System"],"prefix":"10.3390","volume":"12","author":[{"given":"Matthew","family":"Richardson","sequence":"first","affiliation":[{"name":"Interdisciplinary Oncology Program, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hae Jung","family":"Min","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Hong","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Compton","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sze Wing","family":"Mung","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Lohn","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Nuk","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"McCullum","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Portigal-Todd","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aly","family":"Karsan","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dean","family":"Regier","sequence":"additional","affiliation":[{"name":"Department of School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada"},{"name":"Cancer Control Research, BC Cancer, Vancouver, BC V5Z 1L3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A.","family":"Brotto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, University of British Columbia, Vancouver, BC V6Z 2K8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Sun","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"},{"name":"Division of Medical Oncology, Faculty of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada"},{"name":"Department of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kasmintan A.","family":"Schrader","sequence":"additional","affiliation":[{"name":"Hereditary Cancer Program, BC Cancer, Vancouver, BC V5Z 1K1, Canada"},{"name":"Department of Medical Genetics, University of British Columbia, Vancouver, BC V6H 3N1, Canada"},{"name":"Department of Molecular Oncology, BC Cancer, Vancouver, BC V5Z 1G1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1186\/s13058-014-0442-6","article-title":"The Angelina Jolie effect: How high celebrity profile can have a major impact on provision of cancer related services","volume":"16","author":"Evans","year":"2014","journal-title":"Breast Cancer Res."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.amepre.2014.01.002","article-title":"Awareness of cancer susceptibility genetic testing: The 2000, 2005, and 2010 national health interview surveys","volume":"46","author":"Mai","year":"2014","journal-title":"Am. 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