{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T01:45:45Z","timestamp":1760233545968,"version":"build-2065373602"},"reference-count":57,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T00:00:00Z","timestamp":1611619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>A retrospective study was performed to assess the outcomes of a single-fraction adjuvant electronic brachytherapy (e-BT) approach for patients with squamous cell conjunctival carcinoma (SCCC). Forty-seven patients with T1\u2013T3 SCCC were included. All patients underwent surgery followed by a single-fraction adjuvant e-BT with a porTable 50-kV device. Depending on margins, e-BT doses ranged between 18 to 22 Gy prescribed at 2 mm depth, resembling equivalent doses in 2 Gy (EQD2) per fraction of 46\u201366 Gy (\u03b1\/\u03b2 ratio of 8\u201310 Gy and a relative biological effect (RBE) of 1.3). The median age was 69 (29\u201387) years. Most tumors were T1 (40.4%) or T2 (57.5%) with a median size of 7 mm (1.5\u201320). Margins were positive in 40.4% of cases. The median time from surgery to e-BT was nine weeks (0\u201337). After a median follow-up of 24 (17\u201340) months, recurrence occurred in only two patients (6 and 7 months after e-BT), yielding a median disease-free survival (DFS) of 24 (6\u201340) months and DFS at two years of 95.7%. Acute grade 2 conjunctivitis occurred in 25.5%. E-BT is a safe and effective for SCCC treatment, with clinical and logistic advantages compared to classical methods. Longer follow-up and prospective assessment are warranted.<\/jats:p>","DOI":"10.3390\/cancers13030454","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T00:38:16Z","timestamp":1611621496000},"page":"454","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Single-Fraction Adjuvant Electronic Brachytherapy after Resection of Conjunctival Carcinoma"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5929-7270","authenticated-orcid":false,"given":"Gustavo R.","family":"Sarria","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solon","family":"Serpa","sequence":"additional","affiliation":[{"name":"Department of Ophtalmic Oncology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Buitrago","sequence":"additional","affiliation":[{"name":"Department of Ophtalmic Oncology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2054-2360","authenticated-orcid":false,"given":"Paola","family":"Fuentes Rivera","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Department of Ophtalmic Oncology, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5243-4781","authenticated-orcid":false,"given":"Frank A.","family":"Giordano","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7459-7730","authenticated-orcid":false,"given":"Gustavo J.","family":"Sarria","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1038\/eye.2014.79","article-title":"Clinical outcome of advanced squamous cell carcinoma of the conjunctiva","volume":"28","author":"Miller","year":"2014","journal-title":"Eye (Lond.)"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ajo.2016.09.034","article-title":"Conjunctival Tumors in 5002 Cases. Comparative Analysis of Benign Versus Malignant Counterparts. The 2016 James, D. Allen Lecture","volume":"173","author":"Shields","year":"2017","journal-title":"Am. J. Ophthalmol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/sj.bjc.6600451","article-title":"The epidemiology of conjunctival squamous cell carcinoma in Uganda","volume":"87","author":"Newton","year":"2002","journal-title":"Br. J. Cancer"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1111\/tmi.12203","article-title":"Epidemiology of ocular surface squamous neoplasia in Africa","volume":"18","author":"Gichuhi","year":"2013","journal-title":"Trop. Med. Int. Health"},{"key":"ref_5","first-page":"73","article-title":"Epidemiology of squamous cell conjunctival cancer","volume":"6","author":"Sun","year":"1997","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1002\/ijc.23384","article-title":"Elevated risk for squamous cell carcinoma of the conjunctiva among adults with AIDS in the United States","volume":"122","author":"Engels","year":"2008","journal-title":"Int. J. Cancer"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ophtha.2011.08.005","article-title":"Squamous carcinoma and dysplasia of the conjunctiva and cornea: An analysis of 101 cases","volume":"119","author":"Yousef","year":"2012","journal-title":"Ophthalmology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0008-4182(02)80093-X","article-title":"Squamous cell carcinoma of the conjunctiva: Clinicopathological features in 287 cases","volume":"37","author":"Cervantes","year":"2002","journal-title":"Can. J. Ophthalmol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1136\/bjo.2005.077305","article-title":"The aetiology and associations of conjunctival intraepithelial neoplasia","volume":"90","author":"Kiire","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S0161-6420(97)30287-5","article-title":"Late Recurrences and the Necessity for Long-term Follow-up in Corneal and Conjunctival Intraepithelial Neoplasia","volume":"104","author":"Tabin","year":"1997","journal-title":"Ophthalmology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.survophthal.2003.10.008","article-title":"Tumors of the conjunctiva and cornea","volume":"49","author":"Shields","year":"2004","journal-title":"Surv. Ophthalmol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1001\/archopht.1997.01100150810025","article-title":"Surgical management of conjunctival tumors. The 1994 Lynn B. McMahan Lecture","volume":"115","author":"Shields","year":"1997","journal-title":"Arch. Ophthalmol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S0039-6257(05)80054-2","article-title":"Ocular surface squamous neoplasia","volume":"39","year":"1995","journal-title":"Surv. Ophthalmol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1016\/j.ophtha.2012.04.022","article-title":"Predictors of ocular surface squamous neoplasia recurrence after excisional surgery","volume":"119","author":"Galor","year":"2012","journal-title":"Ophthalmology"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s40123-018-0140-z","article-title":"Clinical Management of Ocular Surface Squamous Neoplasia: A Review of the Current Evidence","volume":"7","author":"Cicinelli","year":"2018","journal-title":"Ophthalmol. Ther."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e378","DOI":"10.1016\/S2214-109X(16)30052-3","article-title":"Topical fluorouracil after surgery for ocular surface squamous neoplasia in Kenya: A randomised, double-blind, placebo-controlled trial","volume":"4","author":"Gichuhi","year":"2016","journal-title":"Lancet Global Health"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.ophtha.2008.01.006","article-title":"Topical interferon or surgical excision for the management of primary ocular surface squamous neoplasia","volume":"115","author":"Sturges","year":"2008","journal-title":"Ophthalmology"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0002-9394(14)73021-1","article-title":"Microscopically Controlled Excision of Conjunctival Squamous Cell Carcinoma","volume":"117","author":"Folberg","year":"1994","journal-title":"Am. J. Ophthalmol."},{"key":"ref_19","first-page":"24","article-title":"Update on pharmacotherapy for ocular surface squamous neoplasia","volume":"6","author":"Venkateswaran","year":"2019","journal-title":"Eye Vis. (Lond.)"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1001\/jamaophthalmol.2014.86","article-title":"Plaque radiotherapy in the management of scleral-invasive conjunctival squamous cell carcinoma: An analysis of 15 eyes","volume":"132","author":"Arepalli","year":"2014","journal-title":"JAMA Ophthalmol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"4502","DOI":"10.1120\/jacmp.v15i1.4502","article-title":"A novel approach for superficial intraoperative radiotherapy (IORT) using a 50 kV X-ray source: A technical and case report","volume":"15","author":"Schneider","year":"2014","journal-title":"J. Appl. Clin. Med. Phys."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fonc.2018.00074","article-title":"Intraoperative Radiotherapy With INTRABEAM: Technical and Dosimetric Considerations","volume":"8","author":"Sethi","year":"2018","journal-title":"Front. Oncol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"835","DOI":"10.3332\/ecancer.2018.835","article-title":"Phase I\/II study on kilovoltage surface brachytherapy in conjunctival cancer: Preliminary results","volume":"12","author":"Sarria","year":"2018","journal-title":"Ecancermedicalscience"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.ijrobp.2018.01.115","article-title":"The Inca Trail to the Present: The Development of Radiation Therapy in Peru","volume":"101","author":"Sarria","year":"2018","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/neuros\/nyy018","article-title":"Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma (INTRAGO): An Open-Label, Dose-Escalation Phase I\/II Trial","volume":"84","author":"Giordano","year":"2019","journal-title":"Neurosurgery"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s13014-020-01559-7","article-title":"Intraoperative radiotherapy with low energy x-rays for primary and recurrent soft-tissue sarcomas","volume":"15","author":"Sarria","year":"2020","journal-title":"Radiat. Oncol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"e200249","DOI":"10.1001\/jamaoncol.2020.0249","article-title":"Effect of Delayed Targeted Intraoperative Radiotherapy vs Whole-Breast Radiotherapy on Local Recurrence and Survival: Long-term Results From the TARGIT-A Randomized Clinical Trial in Early Breast Cancer","volume":"6","author":"Vaidya","year":"2020","journal-title":"JAMA Oncol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13014-020-1458-y","article-title":"Intraoperative radiotherapy as an immediate adjuvant treatment of rectal cancer due to limited access to external-beam radiotherapy","volume":"15","author":"Potemin","year":"2020","journal-title":"Radiat. Oncol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.5935\/0004-2749.20170032","article-title":"Adjuvant treatment or primary topical monotherapy for ocular surface squamous neoplasia: A systematic review","volume":"80","author":"Viani","year":"2017","journal-title":"Arq. Bras. Oftalmol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1007\/s10792-018-0943-x","article-title":"Ocular surface squamous neoplasia: Analysis based on the 8th American Joint Committee on Cancer classification","volume":"39","author":"Singh","year":"2019","journal-title":"Int. Ophthalmol."},{"key":"ref_31","first-page":"109","article-title":"Conjunctival Tumors: Review of Clinical Features, Risks, Biomarkers, and Outcomes\u2014The 2017 J. Donald M. Gass Lecture","volume":"6","author":"Shields","year":"2017","journal-title":"Asia Pac. J. Ophthalmol. (Phila)"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/sj.eye.6700331","article-title":"Excision and cryosurgery in the treatment of conjunctival malignant epithelial tumours","volume":"17","author":"Peksayar","year":"2003","journal-title":"Eye (Lond.)"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1097\/ICO.0b013e3182523f61","article-title":"Interferon for ocular surface squamous neoplasia in 81 cases: Outcomes based on the American Joint Committee on Cancer classification","volume":"32","author":"Shields","year":"2013","journal-title":"Cornea"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ophtha.2017.11.021","article-title":"Topical Cidofovir for Treatment-Refractory Ocular Surface Squamous Neoplasia","volume":"125","author":"Ip","year":"2018","journal-title":"Ophthalmology"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/ICO.0b013e3181dee560","article-title":"Treatment of ocular surface squamous cell intraepithelial neoplasia with and without mitomycin C","volume":"30","author":"Birkholz","year":"2011","journal-title":"Cornea"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.ophtha.2013.11.017","article-title":"Surgical versus medical treatment of ocular surface squamous neoplasia: A comparison of recurrences and complications","volume":"121","author":"Nanji","year":"2014","journal-title":"Ophthalmology"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/17469899.2017.1263567","article-title":"Diagnosis and Medical Management of Ocular Surface Squamous Neoplasia","volume":"12","author":"Palioura","year":"2017","journal-title":"Expert. Rev. Ophthalmol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ajo.2018.11.007","article-title":"Comparison of Topical 5-Fluorouracil and Interferon Alfa-2b as Primary Treatment Modalities for Ocular Surface Squamous Neoplasia","volume":"199","author":"Venkateswaran","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"449S","DOI":"10.1016\/S0248-8663(02)00659-8","article-title":"Les diff\u00e9rents interf\u00e9rons: Pharmacologie, m\u00e9canismes d\u2019action, tol\u00e9rance et effets secondaires","volume":"23","author":"Arnaud","year":"2002","journal-title":"Rev. Med. Interne"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1136\/bjophthalmol-2016-309219","article-title":"Topical 1% 5-fluoruracil as a sole treatment of corneoconjunctival ocular surface squamous neoplasia: Long-term study","volume":"101","author":"Parrozzani","year":"2017","journal-title":"Br. J. Ophthalmol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/bjo.2008.153197","article-title":"Topical interferon alpha 2b eye-drops for treatment of ocular surface squamous neoplasia: A dose comparison study","volume":"94","author":"Galor","year":"2010","journal-title":"Br. J. Ophthalmol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/IOP.0b013e31820d872f","article-title":"Electron beam radiation for conjunctival squamous carcinoma","volume":"27","author":"Graue","year":"2011","journal-title":"Ophthalmic. Plast. Reconstr. Surg."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.ijrobp.2010.09.056","article-title":"Ocular risks from orbital and periorbital radiation therapy: A critical review","volume":"79","author":"Jeganathan","year":"2011","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Espensen, C.A., Appelt, A.L., Fog, L.S., Gothelf, A.B., Thariat, J., and Kiilgaard, J.F. (2019). Predicting Visual Acuity Deterioration and Radiation-Induced Toxicities after Brachytherapy for Choroidal Melanomas. Cancers, 11.","DOI":"10.3390\/cancers11081124"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ajo.2018.11.024","article-title":"Management of Invasive Squamous Cell Carcinomas of the Conjunctiva","volume":"200","author":"Santoni","year":"2019","journal-title":"Am. J. Ophthalmol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1136\/bjophthalmol-2014-306327","article-title":"The treatment of carcinoma in situ and squamous cell carcinoma of the conjunctiva with fractionated strontium-90 radiation in a population with a high prevalence of HIV","volume":"99","author":"Lecuona","year":"2015","journal-title":"Br. J. Ophthalmol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ejmp.2018.11.003","article-title":"Pre and post operative radiation protection in Ru-106 brachytherapy ophthalmic plaque surgery and related material shielding properties","volume":"57","author":"Busoni","year":"2019","journal-title":"Phys. Med."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1097\/IAE.0b013e3182509827","article-title":"Radiation dose to the surgeon during plaque brachytherapy","volume":"32","author":"Classic","year":"2012","journal-title":"Retina"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1136\/bjo.2005.068460","article-title":"18 years\u2019 experience with high dose rate strontium-90 brachytherapy of small to medium sized posterior uveal melanoma","volume":"89","author":"Spileers","year":"2005","journal-title":"Br. J. Ophthalmol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.radphyschem.2012.12.025","article-title":"Brachytherapy treatment simulation of strontium-90 and ruthenium-106 plaques on small size posterior uveal melanoma using MCNPX code","volume":"95","author":"Barbosa","year":"2014","journal-title":"Radiat. Phys. Chem."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/0360-3016(88)90257-X","article-title":"Adjunctive radiotherapy with strontium-90 in the treatment of conjunctival squamous cell carcinoma","volume":"14","year":"1988","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_52","unstructured":"(2019, October 30). Common Terminology Criteria for Adverse Events Version 4.03, Available online: https:\/\/evs.nci.nih.gov\/ftp1\/CTCAE\/CTCAE_4.03\/CTCAE_4.03_2010-06-14_QuickReference_8.5x11.pdf."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.ijrobp.2005.01.058","article-title":"Effectiveness of fractionated stereotactic radiotherapy for uveal melanoma","volume":"63","author":"Muller","year":"2005","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.radonc.2011.06.038","article-title":"Fractionated stereotactic radiotherapy for uveal melanoma, late clinical results","volume":"102","author":"Muller","year":"2012","journal-title":"Radiother. Oncol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s13014-018-1088-9","article-title":"Linear accelerator-based stereotactic fractionated photon radiotherapy as an eye-conserving treatment for uveal melanoma","volume":"13","author":"Akbaba","year":"2018","journal-title":"Radiat. Oncol."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Brierley, J.D., Gospodarowicz, M.K., and Wittekind, C. (2017). TNM Classification of Malignant Tumours, Wiley Blackwell. [8th ed.].","DOI":"10.1002\/9780471420194.tnmc26.pub3"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1016\/j.ijrobp.2012.08.005","article-title":"Relative Biologic Effectiveness (RBE) of 50 kV X-rays measured in a phantom for intraoperative tumor-bed irradiation","volume":"85","author":"Liu","year":"2013","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."}],"container-title":["Cancers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6694\/13\/3\/454\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:15:16Z","timestamp":1760159716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6694\/13\/3\/454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,26]]},"references-count":57,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,2]]}},"alternative-id":["cancers13030454"],"URL":"https:\/\/doi.org\/10.3390\/cancers13030454","relation":{},"ISSN":["2072-6694"],"issn-type":[{"type":"electronic","value":"2072-6694"}],"subject":[],"published":{"date-parts":[[2021,1,26]]}}}