{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:00:04Z","timestamp":1790874004637,"version":"4.1.0"},"reference-count":68,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T00:00:00Z","timestamp":1645747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with poor prognosis and increased incidence. Surgical resection R0 remains the most important treatment to prolong survival in PDAC patients. In borderline and locally advanced cancer, vascular resection and reconstruction during pancreatectomy enables achieving R0 resection. This study is a comprehensive review of the literature regarding the role of venous and arterial resection with vascular reconstruction in the treatment of pancreatic cancer. The literature review is focused on the use of venous and arterial resection with immediate vascular reconstruction in pancreaticoduodenectomy. Different types of venous and arterial resections are widely described. Different methods of vascular reconstructions, from primary vessel closure, through end-to-end vascular anastomosis, to interposition grafts with use autologous veins (internal jugular vein, saphenous vein, superficial femoral vein, external or internal iliac veins, inferior mesenteric vein, and left renal vein or gonadal vein), autologous substitute grafts constructed from various parts of parietal peritoneum including falciform ligament, cryopreserved and synthetic allografts. The most attention was given to the most common venous reconstructions, such as end-to-end anastomosis and interposition graft with the use of an autologous vein. Moreover, we presented mortality and morbidity rates as well as vascular patency and survival following pancreatectomy combined with vascular resection reported in cited articles.<\/jats:p>","DOI":"10.3390\/cancers14051193","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T10:00:40Z","timestamp":1645783240000},"page":"1193","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Vascular Resection in Pancreatectomy\u2014Is It Safe and Useful for Patients with Advanced Pancreatic Cancer?"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5495-2969","authenticated-orcid":false,"given":"Beata","family":"Jab\u0142o\u0144ska","sequence":"first","affiliation":[{"name":"Department of Digestive Tract Surgery, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Kr\u00f3l","sequence":"additional","affiliation":[{"name":"Department of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u0142awomir","family":"Mrowiec","sequence":"additional","affiliation":[{"name":"Department of Digestive Tract Surgery, Medical University of Silesia, 40-752 Katowice, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"4846","DOI":"10.3748\/wjg.v24.i43.4846","article-title":"Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes","volume":"24","author":"McGuigan","year":"2018","journal-title":"World J. Gastroenterol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1245\/ASO.2006.08.011","article-title":"Borderline Resectable Pancreatic Cancer: Definitions, Management, and Role of Preoperative Therapy","volume":"13","author":"Varadhachary","year":"2006","journal-title":"Ann. Surg. Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"4602","DOI":"10.1245\/s10434-020-09467-6","article-title":"R Status is a Relevant Prognostic Factor for Recurrence and Survival After Pancreatic Head Resection for Ductal Adenocarcinoma","volume":"28","author":"Crippa","year":"2021","journal-title":"Ann. Surg. Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.surg.2014.02.001","article-title":"Borderline resectable pancreatic cancer: A consensus statement by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"155","author":"Bockhorn","year":"2014","journal-title":"Surgery"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.6004\/jnccn.2014.0106","article-title":"Pancreatic Adenocarcinoma, Version 2.2014: Featured updates to the NCCN guidelines","volume":"12","author":"Tempero","year":"2014","journal-title":"J. Natl. Compr. Cancer Netw."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Kimura, N., Yamada, S., Takami, H., Murotani, K., Yoshioka, I., Shibuya, K., Sonohara, F., Hoshino, Y., Hirano, K., and Watanabe, T. (2020). Optimal Preoperative Multidisciplinary Treatment in Borderline Resectable Pancreatic Cancer. Cancers, 13.","DOI":"10.3390\/cancers13010036"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/bjs.8763","article-title":"\u2018Artery-first\u2019 approaches to pancreatoduodenectomy","volume":"99","author":"Sanjay","year":"2012","journal-title":"Br. J. Surg."},{"key":"ref_8","first-page":"550","article-title":"Radical pancreaticoduodenectomy with resection and reanastomosis of the superior mesen-teric vein","volume":"30","author":"Moore","year":"1951","journal-title":"Surgery"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1001\/archsurg.1963.01310160071012","article-title":"Radical pancreatectomy and portal vein resection. Report of two successful cases with transplantation of portal vein","volume":"87","author":"Asada","year":"1963","journal-title":"Arch. Surg."},{"key":"ref_10","first-page":"307","article-title":"Regional resection of cancer of the pancreas: A new surgical approach","volume":"73","author":"Fortner","year":"1973","journal-title":"Surgery"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ejso.2014.01.010","article-title":"Benefit from synchronous portal-superior mesenteric vein resection during pancreaticoduodenectomy for cancer: A meta-analysis","volume":"40","author":"Yu","year":"2014","journal-title":"Eur. J. Surg. Oncol. (EJSO)"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Shao, Y., Feng, J., Jiang, Y., Hu, Z., Wu, J., Zhang, M., Shen, Y., and Zheng, S. (2021). Feasibility of mesentericoportal vein reconstruction by autologous falciform ligament during pancreaticoduodenectomy\u2014Cohort study. BMC Surg., 21.","DOI":"10.1186\/s12893-020-01019-9"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1007\/s11605-014-2549-6","article-title":"Prosthetic graft for superior mesenteric-portal vein reconstruction in pancreati-coduodenectomy: A retrospective, multicenter study","volume":"18","author":"Liao","year":"2014","journal-title":"J. Gastrointest. Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/jhbp.299","article-title":"Pancreaticoduodenectomy with venous reconstruction using cold-stored vein allografts: Long-term results of a single center experience","volume":"23","author":"Meniconi","year":"2016","journal-title":"J. Hepato-Biliary-Pancreat. Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.avsg.2019.11.008","article-title":"Paneled Saphenous Vein Grafts Compared to Internal Jugular Vein Grafts in Venous Reconstruction after Pancreaticoduodenectomy","volume":"65","author":"Pantoja","year":"2020","journal-title":"Ann. Vasc. Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1007\/s00423-020-02026-3","article-title":"Postoperative results, pathologic outcome, and long-term patency rate of autologous vein reconstruction of the mesentericoportal axis after pancreatectomy","volume":"406","author":"Bultmann","year":"2021","journal-title":"Langenbecks Arch Surg."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5426","DOI":"10.1245\/s10434-021-09716-2","article-title":"Venous Reconstruction During Pancreatectomy Using Polytetrafluoroethylene Grafts: A Single-Center Experience with Standardized Perioperative Management","volume":"28","author":"Garnier","year":"2021","journal-title":"Ann Surg Oncol."},{"key":"ref_18","first-page":"1","article-title":"Peritoneal patch in vascular reconstruction during pancreaticoduodenectomy for pancreatic cancer: A single Centre experience","volume":"17","author":"Pezzullo","year":"2021","journal-title":"Acta Chir Belg."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.ijsu.2018.03.045","article-title":"Autologous falciform ligament graft as A substitute for mesentericoportal vein reconstruction in pancreaticoduodenectomy","volume":"53","author":"Shao","year":"2018","journal-title":"Int. J. Surg."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.jss.2017.05.090","article-title":"The falciform ligament as a graft for portal\u2013superior mesenteric vein reconstruction in pancreatectomy","volume":"218","author":"Zhiying","year":"2017","journal-title":"J. Surg. Res."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2943879","DOI":"10.1155\/2018\/2943879","article-title":"The Falciform Ligament for Mesenteric and Portal Vein Reconstruction in Local Advanced Pancreatic Tumor: A Surgical Guide and Single-Center Experience","volume":"2018","author":"Malinka","year":"2018","journal-title":"HPB Surg."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1097\/SLA.0000000000000959","article-title":"Parietal Peritoneum as an Autologous Substitute for Venous Reconstruction in Hepatopancreatobiliary Surgery","volume":"262","author":"Dokmak","year":"2015","journal-title":"Ann. Surg."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"S343","DOI":"10.1245\/s10434-015-4635-8","article-title":"Pancreaticoduodenectomy with Reconstruction of the Mesentericoportal Vein by the Parietal Peritoneum: \u2018Safi Dokmak Vascular Graft\u2019","volume":"22","author":"Dokmak","year":"2015","journal-title":"Ann. Surg. Oncol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jvs.2009.09.025","article-title":"Techniques and results of portal vein\/superior mesenteric vein reconstruction using femoral and saphenous vein during pancreaticoduodenectomy","volume":"51","author":"Lee","year":"2010","journal-title":"J. Vasc. Surg."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.avsg.2011.11.009","article-title":"Vascular Surgery Collaboration During Pancreaticoduodenectomy with Vascular Reconstruction","volume":"26","author":"Turley","year":"2012","journal-title":"Ann. Vasc. Surg."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1007\/s11605-014-2635-9","article-title":"Patency Rates of Portal Vein\/Superior Mesenteric Vein Reconstruction after Pancreatectomy for Pancreatic Cancer","volume":"18","author":"Krepline","year":"2014","journal-title":"J. Gastrointest. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s00423-014-1182-x","article-title":"Indication for the use of an interposed graft during portal vein and\/or superior mesenteric vein reconstruction in pancreatic resection based on perioperative outcomes","volume":"399","author":"Hirono","year":"2014","journal-title":"Langenbeck\u2019s Arch. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.jvs.2015.01.061","article-title":"Technical risk factors for portal vein reconstruction thrombosis in pancreatic resection","volume":"62","author":"Glebova","year":"2015","journal-title":"J. Vasc. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1111\/hpb.12463","article-title":"Pancreatectomy with vein reconstruction: Technique matters","volume":"17","author":"Dua","year":"2015","journal-title":"HPB"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00423-019-01749-2","article-title":"Comparison of end-to-end anastomosis and interposition graft during pancreatoduodenectomy with portal vein reconstruction for pancreatic ductal adenocarcinoma","volume":"404","author":"Terasaki","year":"2019","journal-title":"Langenbeck\u2019s Arch. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Chan, K.S., Srinivasan, N., Koh, Y.X., Tan, E.K., Teo, J.Y., Lee, S.Y., Cheow, P.C., Jeyaraj, P.R., Chow, P.K.H., and Ooi, L.L.P.J. (2020). Comparison between long and short-term venous patencies after pancreatoduodenectomy or total pancreatectomy with portal\/superior mesenteric vein resection stratified by reconstruction type. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0240737"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.hpb.2020.11.008","article-title":"Graft type for superior mesenteric and portal vein reconstruction in pancreatic surgery\u2014A systematic review","volume":"23","author":"Labori","year":"2020","journal-title":"HPB"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"8740","DOI":"10.3748\/wjg.v19.i46.8740","article-title":"Vascular resection in pancreatic adenocarcinoma with portal or superior mesenteric vein invasion","volume":"19","author":"Pan","year":"2013","journal-title":"World J. Gastroenterol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.gassur.2006.04.002","article-title":"Postoperative morbidity and long-term survival after pan-creaticoduodenectomy with superior mesenterico-portal vein resection","volume":"10","author":"Riediger","year":"2006","journal-title":"J. Gastrointest. Surg."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1007\/s002689900601","article-title":"Who Benefits from Portal Vein Resection during Pancreaticoduodenectomy for Pancreatic Cancer?","volume":"23","author":"Launois","year":"1999","journal-title":"World J. Surg."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.surg.2014.12.002","article-title":"Vein resections > 3 cm during pancreatectomy are associated with poor 1-year patency rates","volume":"157","author":"Fujii","year":"2015","journal-title":"Surgery"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1002\/bjs.9222","article-title":"Planned versus unplanned portal vein resections during pancreaticoduodenectomy for adenocarcinoma","volume":"100","author":"Kim","year":"2013","journal-title":"Br. J. Surg."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.surg.2018.08.025","article-title":"Impact of portal vein resection with splenic vein reconstruction after PTFE on sinistral portal hypertension: Who needs reconstruction?","volume":"165","author":"Tanaka","year":"2019","journal-title":"Surgery"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/bjs.9707","article-title":"Sinistral portal hypertension after pancreaticoduodenectomy with splenic vein ligation","volume":"102","author":"Ono","year":"2015","journal-title":"Br. J. Surg."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.surg.2020.04.033","article-title":"The left splenorenal venous shunt decreases clinical signs of sinistral portal hypertension associated with splenic vein ligation during pancreaticoduodenectomy with venous resection","volume":"168","author":"Addeo","year":"2020","journal-title":"Surgery"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1007\/s00268-017-3916-8","article-title":"Significance of Simultaneous Splenic Artery Resection in Left-Sided Portal Hypertension After Pancreaticoduodenectomy with Combined Portal Vein Resection","volume":"41","author":"Gyoten","year":"2017","journal-title":"World J. Surg."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"17448","DOI":"10.3748\/wjg.v20.i46.17448","article-title":"Pancreaticoduodenectomy with vascular reconstruction for adenocarcinoma of the pancreas with borderline resectability","volume":"20","author":"Cheung","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s00423-014-1194-6","article-title":"Outcome of superior mesenteric-portal vein resection during pancreatectomy for borderline ductal adenocarcinoma: Results of a prospective comparative study","volume":"399","author":"Selvaggi","year":"2014","journal-title":"Langenbeck\u2019s Arch. Surg."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/bjs.9799","article-title":"Portal or superior mesenteric vein resection in pancreatoduodenectomy for pancreatic head carcinoma","volume":"102","author":"Murakami","year":"2015","journal-title":"Br. J. Surg."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/ans.12502","article-title":"Long-term outcome of portomesenteric vein invasion and prognostic factors in pancreas head adenocarcinoma","volume":"85","author":"Jeong","year":"2015","journal-title":"ANZ J. Surg."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/S1499-3872(15)60400-3","article-title":"Pancreaticoduodenectomy with portal vein\/superior mesenteric vein resection for patients with pancreatic cancer with venous invasion","volume":"14","author":"Wang","year":"2015","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1245\/s10434-014-4304-3","article-title":"Pancreatic Adenocarcinoma with Venous Involvement: Is Up-Front Synchronous Portal-Superior Mesenteric Vein Resection Still Justified? A Survey of the Association Fran\u00e7aise de Chirurgie","volume":"22","author":"Delpero","year":"2015","journal-title":"Ann. Surg. Oncol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.hbpd.2019.06.004","article-title":"The impact of extent of pancreatic and venous resection on survival for patients with pancreatic cancer","volume":"18","author":"Serenari","year":"2019","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/bjs.9969","article-title":"Meta-analysis of benefits of portal\u2013superior mesenteric vein resection in pancreatic resection for ductal adenocarcinoma","volume":"103","author":"Giovinazzo","year":"2016","journal-title":"Br. J. Surg."},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Peng, C., Zhou, D., Meng, L., Cao, Y., Zhang, H., Pan, Z., and Lin, C. (2019). The value of combined vein resection in pancreaticoduodenectomy for pancreatic head carcinoma: A meta-analysis. BMC Surg., 19.","DOI":"10.1186\/s12893-019-0540-6"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Fancellu, A., Petrucciani, N., Porcu, A., Deiana, G., Sanna, V., Ninniri, C., Perra, T., Celoria, V., and Nigri, G. (2020). The Impact on Survival and Morbidity of Portal\u2013Mesenteric Resection During Pancreaticoduodenectomy for Pancreatic Head Adenocarcinoma: A Systematic Review and Meta-Analysis of Comparative Studies. Cancers, 12.","DOI":"10.3390\/cancers12071976"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"e27438","DOI":"10.1097\/MD.0000000000027438","article-title":"The impact of venous resection in pancreatoduodectomy: A systematic review and meta-analysis","volume":"100","author":"Filho","year":"2021","journal-title":"Medicine"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.hpb.2020.04.005","article-title":"Arterial resections in pancreatic cancer\u2014Systematic review and meta-analysis","volume":"22","author":"Stefura","year":"2020","journal-title":"HPB"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1007\/s00268-010-0699-6","article-title":"Vascular Reconstruction During Pancreatoduodenectomy for Ductal Adenocarcinoma of the Pancreas Improves Resectability but does not Achieve Cure","volume":"34","author":"Ouaissi","year":"2010","journal-title":"World J. Surg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/bjs.7270","article-title":"Arterial en bloc resection for pancreatic carcinoma","volume":"98","author":"Bockhorn","year":"2010","journal-title":"Br. J. Surg."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/jso.21769","article-title":"Is the need for an arterial resection a contraindication to pancreatic resection for locally advanced pancreatic adenocarcinoma? A case-matched controlled study","volume":"103","author":"Bachellier","year":"2011","journal-title":"J. Surg. Oncol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1097\/SLA.0000000000003010","article-title":"Pancreatectomy with Arterial Resection for Pancreatic Adenocarcinoma: How Can It Be Done Safely and with Which Outcomes? A Single Institution\u2019s Experience with 118 Patients","volume":"271","author":"Bachellier","year":"2020","journal-title":"Ann. Surg."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1007\/s00423-016-1488-y","article-title":"Locally advanced pancreatic duct adenocarcinoma: Pancreatectomy with planned arterial resection based on axial arterial encasement","volume":"401","author":"Perinel","year":"2016","journal-title":"Langenbeck\u2019s Arch. Surg."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ijsu.2017.01.042","article-title":"Vascular resection in pancreaticoduodenectomy for periampullary cancers. A 10 year retrospective cohort study","volume":"39","author":"Podda","year":"2017","journal-title":"Int. J. Surg."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.hpb.2018.10.004","article-title":"Neoadjuvant therapy and major arterial resection for potentially reconstructable arterial involvement by stage 3 adenocarcinoma of the pancreas","volume":"21","author":"Loveday","year":"2019","journal-title":"HPB"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.hpb.2018.07.017","article-title":"Pancreatectomy with arterial resection is superior to palliation in patients with borderline resectable or locally advanced pancreatic cancer","volume":"21","author":"Rangelova","year":"2019","journal-title":"HPB"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.jamcollsurg.2018.05.001","article-title":"Indications and Perioperative Outcomes for Pancreatectomy with Arterial Resection","volume":"227","author":"Tee","year":"2018","journal-title":"J. Am. Coll. Surg."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e22115","DOI":"10.1097\/MD.0000000000022115","article-title":"Arterial resection during pancreatectomy for pancreatic ductal adenocarcinoma with arterial invasion: A single-center experience with 109 patients","volume":"99","author":"Kwon","year":"2020","journal-title":"Medicine"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.hpb.2016.11.013","article-title":"Pancreatoduodenectomy with venous or arterial resection: A NSQIP propensity score analysis","volume":"19","author":"Beane","year":"2017","journal-title":"HPB"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Ingram, M.A., Lauren, B.N., Pumpalova, Y., Park, J., Lim, F., Bates, S.E., Kastrinos, F., Manji, G.A., Kong, C.Y., and Hur, C. (2022). Cost-effectiveness of neoadjuvant FOLFIRINOX versus gemcitabine plus nab-paclitaxel in borderline resectable\/locally advanced pancreatic cancer patients. Cancer Rep., e1565.","DOI":"10.1002\/cnr2.1565"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/SLA.0000000000002600","article-title":"Predictors of Resectability and Survival in Patients with Borderline and Locally Advanced Pancreatic Cancer who Underwent Neoadjuvant Treatment with FOLFIRINOX","volume":"269","author":"Michelakos","year":"2019","journal-title":"Ann. Surg."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.21037\/jgo-2020-slapc-04","article-title":"Resectable, borderline, and locally advanced pancreatic cancer\u2014\u201cthe good, the bad, and the ugly\u201d candidates for surgery?","volume":"12","author":"Bratlie","year":"2021","journal-title":"J. Gastrointest. Oncol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/SLA.0000000000000867","article-title":"Radiological and Surgical Implications of Neoadjuvant Treatment with FOLFIRINOX for Locally Advanced and Borderline Resectable Pancreatic Cancer","volume":"261","author":"Ferrone","year":"2015","journal-title":"Ann. Surg."}],"container-title":["Cancers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/5\/1193\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:27:13Z","timestamp":1760135233000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/5\/1193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,25]]},"references-count":68,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["cancers14051193"],"URL":"https:\/\/doi.org\/10.3390\/cancers14051193","relation":{},"ISSN":["2072-6694"],"issn-type":[{"value":"2072-6694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,25]]}}}