{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:53:32Z","timestamp":1791478412516,"version":"4.3.4"},"reference-count":39,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Janssen (France)","award":["IPC-UF0230"],"award-info":[{"award-number":["IPC-UF0230"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Cancer patients commonly experience psychological distress that may increase with the current COVID-19 pandemic. This prospective study aimed to measure post-traumatic stress disorder (PTSD) and anxiety in cancer patients following France\u2019s first COVID-19-related lockdown, together with associated factors. Cancer patients receiving outpatient treatment or post-treatment follow-up completed a questionnaire which measured, among other things, PTSD (IES-R), anxiety (State-Trait Anxiety Inventory), and fear of cancer recurrence (FCR). Of the 1097 patients included in the study, 14.7% and 30.5% suffered from PTSD and anxiety, respectively. Patients afraid to come to hospital due to the risk of COVID-19 transmission (OR = 3.49, p &lt; 0.001), those with a negative lockdown experience (OR = 0.98, p &lt; 0.001), women (OR = 1.97; p = 0.009), and patients living alone (OR = 1.63, p = 0.045) were all more likely to have PTSD. Older patients (OR = 1.65, p = 0.020), women (OR = 1.62, p = 0.018), those with a higher FCR score (OR = 5.02, p &lt; 0.001), patients unsatisfied with their cancer management (OR = 2.36, p &lt; 0.001), and those afraid to come to hospital due to COVID-19 (OR = 2.43, p &lt; 0.001) all had a higher risk of anxiety. These results provide a greater understanding of the psychological consequences of the COVID-19 pandemic in cancer patients and highlight the need to better integrate psychosocial support in pandemic response measures in order to guide health systems.<\/jats:p>","DOI":"10.3390\/cancers14071794","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T21:33:03Z","timestamp":1648762383000},"page":"1794","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The Psychological Distress of Cancer Patients following the COVID-19 Pandemic First Lockdown: Results from a Large French Survey"],"prefix":"10.3390","volume":"14","author":[{"given":"Patricia","family":"Marino","sequence":"first","affiliation":[{"name":"Institut Paoli-Calmettes, SESSTIM, INSERM, IRD, Aix Marseille University, 13009 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-0943","authenticated-orcid":false,"given":"Rajae","family":"Touzani","sequence":"additional","affiliation":[{"name":"Institut Paoli-Calmettes, SESSTIM, INSERM, IRD, Aix Marseille University, 13009 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jihane","family":"Pakradouni","sequence":"additional","affiliation":[{"name":"Department of Clinical Research and Innovation, Institut Paoli-Calmettes, 13009 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Ben Soussan","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, Institut Paoli-Calmettes, 13009 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwenaelle","family":"Gravis","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Institut Paoli-Calmettes, Aix-Marseille University, CRCM, 13009 Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1038\/s41591-020-0874-8","article-title":"Caring for patients with cancer in the COVID-19 era","volume":"26","author":"Hoes","year":"2020","journal-title":"Nat. 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