{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T01:02:58Z","timestamp":1776214978415,"version":"3.50.1"},"reference-count":39,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T00:00:00Z","timestamp":1651017600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: Positron emission tomography\/computed tomography with fluorodeoxyglucose (F-18) (FDG PET\/CT) is increasingly used in Kaposi sarcoma (KS), but its value has not been assessed. Objectives: In this study, we aimed to evaluate the diagnostic accuracy of FDG PET\/CT to define the extent of disease in KS. Methods: Consecutive patients with KS referred to our department for FDG PET\/CT were included. The diagnostic accuracy of FDG PET\/CT for cutaneous and extra-cutaneous KS staging was assessed on a per lesion basis compared to staging obtained from clinical examination, standard imaging, endoscopy, histological analyses, and follow-up. Results: From 2007 to 2017, 75 patients with FDG PET\/CT were analyzed. The sensitivity and specificity of FDG PET\/CT for the overall detection of KS lesions were 71 and 98%, respectively. Sensitivity and specificity were 100 and 85% for lymph nodes, 87 and 98% for bone, 87 and 100% for lungs, and 100 and 100% for muscle involvement, whereas sensitivity was only 17% to detect KS digestive involvement. The sensitivity of the diagnostic for KS cutaneous involvement increased from 73 to 88% when using a whole-body examination. Conclusion: FDG PET\/CT showed good sensitivity and specificity for KS staging (digestive involvement excepted) and could be used for staging patients with active KS.<\/jats:p>","DOI":"10.3390\/cancers14092189","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T13:40:57Z","timestamp":1651066857000},"page":"2189","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Yield of FDG PET\/CT for Defining the Extent of Disease in Patients with Kaposi Sarcoma"],"prefix":"10.3390","volume":"14","author":[{"given":"Louise","family":"Pesqu\u00e9","sequence":"first","affiliation":[{"name":"Nuclear Medicine Department, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-3377","authenticated-orcid":false,"given":"Julie","family":"Delyon","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"INSERM HIPI Team 1, U976, Saint Louis University Hospital, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"Universit\u00e9 de Paris Cit\u00e9, 75006 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Coralie","family":"Lheure","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Paris Cit\u00e9, 75006 Paris, France"},{"name":"Department of Dermatology, Cochin University Hospital, 27, Rue du Faubourg-Saint-Jacques, 75014 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barouyr","family":"Baroudjian","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maxime","family":"Battistella","sequence":"additional","affiliation":[{"name":"INSERM HIPI Team 1, U976, Saint Louis University Hospital, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"Universit\u00e9 de Paris Cit\u00e9, 75006 Paris, France"},{"name":"Department of Pathology, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Merlet","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Department, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"Universit\u00e9 de Paris Cit\u00e9, 75006 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9leste","family":"Lebb\u00e9","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"INSERM HIPI Team 1, U976, Saint Louis University Hospital, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"Universit\u00e9 de Paris Cit\u00e9, 75006 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Vercellino","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Department, Saint Louis University Hospital, Assistance-Publique H\u00f4pitaux de Paris, 1 Avenue Claude Vellefaux, 75010 Paris, France"},{"name":"Universit\u00e9 de Paris, INSERM, UMR_S942 MASCOT, 75006 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,4,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e165","DOI":"10.1016\/j.clon.2017.05.008","article-title":"Iatrogenic Kaposi\u2019s Sarcoma: A Retrospective Cohort Study in an Italian Tertiary Care Centre","volume":"29","author":"Brambilla","year":"2017","journal-title":"Clin. 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Dermatol."}],"container-title":["Cancers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/9\/2189\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:02:21Z","timestamp":1760137341000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/9\/2189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,27]]},"references-count":39,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2022,5]]}},"alternative-id":["cancers14092189"],"URL":"https:\/\/doi.org\/10.3390\/cancers14092189","relation":{},"ISSN":["2072-6694"],"issn-type":[{"value":"2072-6694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,27]]}}}