{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T13:57:57Z","timestamp":1778767077900,"version":"3.51.4"},"reference-count":24,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T00:00:00Z","timestamp":1653523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010344","name":"Aage and Johanne Louis-Hansens Fond","doi-asserted-by":"publisher","award":["20-2B-6754"],"award-info":[{"award-number":["20-2B-6754"]}],"id":[{"id":"10.13039\/501100010344","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: Endorectal ultrasound (ERUS) is an important tool when evaluating complex rectal adenomas and rectal cancer, and the accuracy is improved by adding elastography measurements. A high interobserver agreement is imperative in clinical practice. Therefore, the aim of this study was to evaluate interobserver agreement assessed on real-time images. Additionally, we investigated the intra- and interobserver agreement between experienced and inexperienced observers. Materials and methods: We prospectively included patients referred to an ERUS at the Department of Radiology with a complex rectal polyp or suspected rectal malignancy. Two operators independently scanned each patient in turn. Furthermore, four observers assessed previously obtained images using three different methods for placing the region of interest (ROI). Three months later, the four observers reassessed the images to assess intraobserver variability. Results: A total of 19 patients were included for live assessment. Agreement of tumor classification was substantial for T stage (kappa: 0.86) and fair for N stage (kappa: 0.73), with an absolute agreement for T and N stages of 84% and 89%, respectively. Agreement of SWE was good for Emean (ICC 0.94, 95% CI 0.86\u20130.98) and fair for Emax (ICC 0.85, 95% CI 0.66\u20130.94). Intra- and interobserver agreement between inexperienced and experienced observers showed good to excellent agreement with all ROI methods. Conclusion: Interobserver agreement is high in SWE when performed in a clinical setting. We found the best agreement using the mean value of several ROIs. Intra- and interobserver agreement was high regardless of operator experience.<\/jats:p>","DOI":"10.3390\/cancers14112633","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T08:50:22Z","timestamp":1653555022000},"page":"2633","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Intra- and Interobserver Variability of Shear Wave Elastography in Rectal Cancer"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3463-8574","authenticated-orcid":false,"given":"Martina Kastrup","family":"Loft","sequence":"first","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, Campusvej 55, 5000 Odense, Denmark"},{"name":"Danish Colorectal Cancer Center South, Lillebaelt Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5167-7968","authenticated-orcid":false,"given":"Malene Roland Vils","family":"Pedersen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, Campusvej 55, 5000 Odense, Denmark"},{"name":"Danish Colorectal Cancer Center South, Lillebaelt Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0927-4609","authenticated-orcid":false,"given":"Peter","family":"Grimm","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas Hoffmann","family":"Lauritzen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Dam","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5182-5545","authenticated-orcid":false,"given":"S\u00f8ren Rafael","family":"Rafaelsen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Lillebaelt Hospital, Clinical Cancer Centre, University Hospital of Southern Denmark, Beriderbakken 4, 7100 Vejle, Denmark"},{"name":"Department of Regional Health Research, University of Southern Denmark, Campusvej 55, 5000 Odense, Denmark"},{"name":"Danish Colorectal Cancer Center South, Lillebaelt Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"ref_1","first-page":"iv22","article-title":"Rectal Cancer: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow-up","volume":"28","author":"Wyrwicz","year":"2017","journal-title":"ESMO Updat. 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