{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:38:01Z","timestamp":1792611481470,"version":"4.5.0"},"reference-count":28,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T00:00:00Z","timestamp":1656460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>In 2019, the Global Burden of Disease (GBD) estimated that prostate cancer (PC) was the 16th most common cause of death globally in males. In Mexico, PC epidemiology has been studied by a number of metrics and over various periods, although without including the most up-to-date estimates. Herein, we describe and compare the burdens and trends of PC in Mexico and its 32 states from 2000 to 2019. For this study, we extracted online available data from the GBD 2019 to estimate the crude and age-standardized rates (ASR per 100,000 people) of the incidence and mortality of PC. In Mexico, PC caused 27.1 thousand (95% uncertainty intervals, 20.6\u201336.0 thousand) incident cases and 9.2 thousand (7.7\u201312.7 thousand) deaths in males of all ages in 2019. Among the states, Sinaloa had the greatest ASR of incidence, and Guerrero had the highest mortality. The burden of PC showed an increasing trend, although the magnitude of change differed between metrics and locations. We found both an increasing national trend and subnational variation in the burden of PC. Our results confirm the need for updated and timely estimates to design effective diagnostic and treatment campaigns in locations where the burden of PC is the highest.<\/jats:p>","DOI":"10.3390\/cancers14133184","type":"journal-article","created":{"date-parts":[[2022,6,29]],"date-time":"2022-06-29T20:47:56Z","timestamp":1656535676000},"page":"3184","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Incidence, Mortality, and Trends of Prostate Cancer in Mexico from 2000 to 2019: Results from the Global Burden of Disease Study 2019"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8411-0957","authenticated-orcid":false,"given":"Saul A.","family":"Beltran-Ontiveros","sequence":"first","affiliation":[{"name":"Posgrado en Ciencias Biom\u00e9dicas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80010, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3695-8766","authenticated-orcid":false,"given":"Martha A.","family":"Fernandez-Galindo","sequence":"additional","affiliation":[{"name":"Doctorado en Gen\u00e9tica Humana, Departamento de Biolog\u00eda Molecular y Gen\u00f3mica, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico"},{"name":"Instituto de Gen\u00e9tica Humana \u201cDr. Enrique Corona Rivera\u201d, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose M.","family":"Moreno-Ortiz","sequence":"additional","affiliation":[{"name":"Instituto de Gen\u00e9tica Humana \u201cDr. Enrique Corona Rivera\u201d, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara 44340, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Contreras-Gutierrez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y Docencia en Ciencias de la Salud, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80030, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus","family":"Madue\u00f1a-Molina","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80246, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliakym","family":"Arambula-Meraz","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica y Biolog\u00eda Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80010, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9927-5917","authenticated-orcid":false,"given":"Emir","family":"Leal-Leon","sequence":"additional","affiliation":[{"name":"Laboratorio de Gen\u00e9tica y Biolog\u00eda Molecular, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80010, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delia M.","family":"Becerril-Camacho","sequence":"additional","affiliation":[{"name":"Laboratorio de Biomedicina, Universidad Aut\u00f3noma de Occidente, Unidad Regional Culiac\u00e1n, Culiac\u00e1n Rosales 80020, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4320-9619","authenticated-orcid":false,"given":"Veronica J.","family":"Picos-Cardenas","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80246, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Angulo-Rojo","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n Rosales 80246, Sinaloa, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana Z.","family":"Velazquez","sequence":"additional","affiliation":[{"name":"Departamento de Biomedicina Molecular, Centro de Investigaci\u00f3n y de Estudios Avanzados, Gustavo A. Madero 07360, Ciudad de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Jimenez-Trejo","sequence":"additional","affiliation":[{"name":"Laboratorio de Morfolog\u00eda Celular y Tisular, Instituto Nacional de Pediatr\u00eda, Coyoac\u00e1n 04530, Ciudad de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Gallardo-Vera","sequence":"additional","affiliation":[{"name":"Laboratorio de Biolog\u00eda Molecular y Bioseguridad Nivel III, Centro M\u00e9dico Naval, Coyoac\u00e1n 04470, Ciudad de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2302-1982","authenticated-orcid":false,"given":"Daniel","family":"Diaz","sequence":"additional","affiliation":[{"name":"Centro de Ciencias de la Complejidad (C3), Universidad Nacional Aut\u00f3noma de M\u00e9xico, Coyoac\u00e1n 04510, Ciudad de M\u00e9xico, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,29]]},"reference":[{"key":"ref_1","unstructured":"Ferlay, J., Ervik, M., Lam, F., Colombet, M., Pi\u00f1eros, M., Znaor, A., Soerjomataram, I., and Bray, F. 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