{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T19:59:52Z","timestamp":1787428792437,"version":"build-2736575974"},"reference-count":203,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Canada Research Chairs program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Long-term memory disturbances are amongst the most common and disruptive cognitive symptoms experienced by breast cancer survivors following chemotherapy. To date, most clinical assessments of long-term memory dysfunction in breast cancer survivors have utilized basic verbal and visual memory tasks that do not capture the complexities of everyday event memories. Complex event memories, including episodic memory and autobiographical memory, critically rely on hippocampal processing for encoding and retrieval. Systemic chemotherapy treatments used in breast cancer commonly cause neurotoxicity within the hippocampus, thereby creating a vulnerability to memory impairment. We review structural and functional neuroimaging studies that have identified disruptions in the recollection network and related episodic memory impairments in chemotherapy-treated breast cancer survivors, and argue for the need to better characterize hippocampally mediated memory dysfunction following chemotherapy treatments. Given the importance of autobiographical memory for a person\u2019s sense of identity, ability to plan for the future, and general functioning, under-appreciation of how this type of memory is impacted by cancer treatment can lead to overlooking or minimizing the negative experiences of breast cancer survivors, and neglecting a cognitive domain that may benefit from intervention strategies.<\/jats:p>","DOI":"10.3390\/cancers14194752","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T21:03:10Z","timestamp":1664485390000},"page":"4752","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Episodic Memory and Recollection Network Disruptions Following Chemotherapy Treatment in Breast Cancer Survivors: A Review of Neuroimaging Findings"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0310-5540","authenticated-orcid":false,"given":"Meenakshie","family":"Bradley-Garcia","sequence":"first","affiliation":[{"name":"School of Psychology, University of Ottawa, Ottawa, ON K1N 6N5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Winocur","sequence":"additional","affiliation":[{"name":"Rotman Research Institute, Baycrest Centre, Toronto, ON M6A 2E1, Canada"},{"name":"Department of Psychology, Department of Psychiatry, University of Toronto, Toronto, ON M5S 3G3, Canada"},{"name":"Department of Psychology, Trent University, Peterborough, ON K9J 7B8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7952-3175","authenticated-orcid":false,"given":"Melanie J.","family":"Sekeres","sequence":"additional","affiliation":[{"name":"School of Psychology, University of Ottawa, Ottawa, ON K1N 6N5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3322\/caac.21258","article-title":"Clinical Characteristics, Pathophysiology, and Management of Noncentral Nervous System Cancer-Related Cognitive Impairment in Adults: Cancer-Related Cognitive Impairment","volume":"65","author":"Wefel","year":"2015","journal-title":"CA A Cancer J. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1002\/pon.3214","article-title":"Chemotherapy and Cognitive Complaints in Women with Breast Cancer","volume":"22","author":"Pullens","year":"2013","journal-title":"Psycho-Oncology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1200\/JCO.2012.43.0116","article-title":"Cancer- and Cancer Treatment\u2013Associated Cognitive Change: An Update on the State of the Science","volume":"30","author":"Ahles","year":"2012","journal-title":"JCO"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"102","DOI":"10.3109\/09540261.2013.864260","article-title":"Prevalence, Mechanisms, and Management of Cancer-Related Cognitive Impairment","volume":"26","author":"Janelsins","year":"2014","journal-title":"Int. Rev. Psychiatry"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1093\/annonc\/mdf241","article-title":"Late Effects of Adjuvant Chemotherapy on Cognitive Function: A Follow-up Study in Breast Cancer Patients","volume":"13","author":"Schagen","year":"2002","journal-title":"Ann. Oncol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1200\/JCO.2002.20.2.485","article-title":"Neuropsychologic Impact of Standard-Dose Systemic Chemotherapy in Long-Term Survivors of Breast Cancer and Lymphoma","volume":"20","author":"Ahles","year":"2002","journal-title":"JCO"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.ctrv.2012.05.002","article-title":"Objective and Subjective Cognitive Impairment Following Chemotherapy for Cancer: A Systematic Review","volume":"38","author":"Hutchinson","year":"2012","journal-title":"Cancer Treat. Rev."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1053\/j.seminoncol.2011.03.014","article-title":"An Update on Cancer- and Chemotherapy-Related Cognitive Dysfunction: Current Status","volume":"38","author":"Janelsins","year":"2011","journal-title":"Semin. Oncol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fonc.2015.00059","article-title":"A Meta-Analysis of Cognitive Impairment and Decline Associated with Adjuvant Chemotherapy in Women with Breast Cancer","volume":"5","author":"Ono","year":"2015","journal-title":"Front. Oncol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bandc.2005.05.001","article-title":"The Nature and Severity of Cognitive Impairment Associated with Adjuvant Chemotherapy in Women with Breast Cancer: A Meta-Analysis of the Current Literature","volume":"59","author":"Falleti","year":"2005","journal-title":"Brain Cogn."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3322\/caac.21319","article-title":"American Cancer Society\/American Society of Clinical Oncology Breast Cancer Survivorship Care Guideline","volume":"66","author":"Runowicz","year":"2016","journal-title":"CA Cancer J. Clin."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ejon.2012.06.002","article-title":"Impact of Perceived Cognitive Impairment in Breast Cancer Survivors","volume":"17","author":"Habermann","year":"2013","journal-title":"Eur. J. Oncol. Nurs."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1007\/s10549-011-1888-1","article-title":"Global and Focal Brain Volume in Long-Term Breast Cancer Survivors Exposed to Adjuvant Chemotherapy","volume":"132","author":"Koppelmans","year":"2012","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1038\/bjc.2015.243","article-title":"Long-Term Subjective Cognitive Functioning Following Adjuvant Systemic Treatment: 7-9 Years Follow-up of a Nationwide Cohort of Women Treated for Primary Breast Cancer","volume":"113","author":"Amidi","year":"2015","journal-title":"Br. J. Cancer"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3109\/07380577.2010.533251","article-title":"Identification of Mild Cognitive Impairments in Cancer Survivors","volume":"25","author":"Baxter","year":"2011","journal-title":"Occup. Ther. Health Care"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s10549-006-9380-z","article-title":"Altered Frontocortical, Cerebellar, and Basal Ganglia Activity in Adjuvant-Treated Breast Cancer Survivors 5\u201310 Years after Chemotherapy","volume":"103","author":"Silverman","year":"2007","journal-title":"Breast Cancer Res. Treat."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/hbm.21102","article-title":"Cerebral Hyporesponsiveness and Cognitive Impairment 10 Years after Chemotherapy for Breast Cancer","volume":"32","author":"Reneman","year":"2011","journal-title":"Hum. Brain Mapp."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1002\/hbm.21422","article-title":"Late Effects of High-Dose Adjuvant Chemotherapy on White and Gray Matter in Breast Cancer Survivors: Converging Results from Multimodal Magnetic Resonance Imaging","volume":"33","author":"Reneman","year":"2012","journal-title":"Hum. Brain Mapp."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11682-014-9305-0","article-title":"Neurotoxicity in Breast Cancer Survivors \u226510 Years Post-Treatment Is Dependent on Treatment Type","volume":"9","author":"Koppelmans","year":"2015","journal-title":"Brain Imaging Behav."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3389\/fphar.2017.00138","article-title":"Biomarkers Associated with Cognitive Impairment in Treated Cancer Patients: Potential Predisposition and Risk Factors","volume":"8","author":"Castel","year":"2017","journal-title":"Front. Pharmacol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/B978-0-12-802973-2.00017-3","article-title":"Neuroepidemiology of Cancer and Treatment-Related Neurocognitive Dysfunction in Adult-Onset Cancer Patients and Survivors","volume":"138","author":"McDonald","year":"2016","journal-title":"Handb. Clin. Neurol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.neuroscience.2015.06.016","article-title":"Chemotherapy, Cognitive Impairment and Hippocampal Toxicity","volume":"309","author":"Dietrich","year":"2015","journal-title":"Neuroscience"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1093\/annonc\/mdv206","article-title":"Association of Proinflammatory Cytokines and Chemotherapy-Associated Cognitive Impairment in Breast Cancer Patients: A Multi-Centered, Prospective, Cohort Study","volume":"26","author":"Cheung","year":"2015","journal-title":"Ann. Oncol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1667\/RR3112","article-title":"Radiation Response of Neural Precursor Cells: Linking Cellular Sensitivity to Cell Cycle Checkpoints, Apoptosis and Oxidative Stress","volume":"161","author":"Limoli","year":"2004","journal-title":"Radiat. Res."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"112233","DOI":"10.1016\/j.bbr.2019.112233","article-title":"Chemobrain in Rats: Behavioral, Morphological, Oxidative and Inflammatory Effects of Doxorubicin Administration","volume":"378","author":"Cardoso","year":"2020","journal-title":"Behav. Brain Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1158\/1078-0432.CCR-11-2000","article-title":"Impaired Cognitive Function and Hippocampal Neurogenesis Following Cancer Chemotherapy","volume":"18","author":"Christie","year":"2012","journal-title":"Clin. Cancer Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1158\/0008-5472.CAN-14-2237","article-title":"Stem Cell Transplantation Reverses Chemotherapy-Induced Cognitive Dysfunction","volume":"75","author":"Acharya","year":"2015","journal-title":"Cancer Res."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.bbr.2016.08.039","article-title":"5-Fluorouracil Chemotherapy Upregulates Cytokines and Alters Hippocampal Dendritic Complexity in Aged Mice","volume":"316","author":"Groves","year":"2017","journal-title":"Behav. Brain Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"419","DOI":"10.5607\/en.2018.27.5.419","article-title":"Chronic Treatment with Combined Chemotherapeutic Agents Affects Hippocampal Micromorphometry and Function in Mice, Independently of Neuroinflammation","volume":"27","author":"Kang","year":"2018","journal-title":"Exp. Neurobiol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1007\/s00213-021-05977-7","article-title":"Animal Models of Chemotherapy-Induced Cognitive Decline in Preclinical Drug Development","volume":"238","author":"John","year":"2021","journal-title":"Psychopharmacology"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"118071","DOI":"10.1016\/j.lfs.2020.118071","article-title":"Chemotherapy-Induced Cognitive Impairment (CICI): An Overview of Etiology and Pathogenesis","volume":"258","author":"Mounier","year":"2020","journal-title":"Life Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1038\/4151030a","article-title":"Functional Neurogenesis in the Adult Hippocampus","volume":"415","author":"Schinder","year":"2002","journal-title":"Nature"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nn1847","article-title":"Preferential Incorporation of Adult-Generated Granule Cells into Spatial Memory Networks in the Dentate Gyrus","volume":"10","author":"Kee","year":"2007","journal-title":"Nat. Neurosci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.cell.2009.10.020","article-title":"Adult Neurogenesis Modulates the Hippocampus-Dependent Period of Associative Fear Memory","volume":"139","author":"Kitamura","year":"2009","journal-title":"Cell"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/S0896-6273(01)00523-2","article-title":"Deficient Neurogenesis in Forebrain-Specific Presenilin-1 Knockout Mice Is Associated with Reduced Clearance of Hippocampal Memory Traces","volume":"32","author":"Feng","year":"2001","journal-title":"Neuron"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/hipo.22054","article-title":"Age-Dependent Effects of Hippocampal Neurogenesis Suppression on Spatial Learning","volume":"23","author":"Akers","year":"2013","journal-title":"Hippocampus"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"10838","DOI":"10.1038\/ncomms10838","article-title":"Neurogenesis-Mediated Forgetting Minimizes Proactive Interference","volume":"7","author":"Epp","year":"2016","journal-title":"Nat. Commun."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/hipo.10103","article-title":"Neurogenesis May Relate to Some but Not All Types of Hippocampal-Dependent Learning","volume":"12","author":"Shors","year":"2002","journal-title":"Hippocampus"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1002\/hipo.20163","article-title":"Inhibition of Neurogenesis Interferes with Hippocampus-Dependent Memory Function","volume":"16","author":"Winocur","year":"2006","journal-title":"Hippocampus"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nrn2822","article-title":"New Neurons and New Memories: How Does Adult Hippocampal Neurogenesis Affect Learning and Memory?","volume":"11","author":"Deng","year":"2010","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Dupret, D., Revest, J.-M., Koehl, M., Ichas, F., Giorgi, F.D., Costet, P., Abrous, D.N., and Piazza, P.V. (2008). Spatial Relational Memory Requires Hippocampal Adult Neurogenesis. PLoS ONE, 3.","DOI":"10.1371\/journal.pone.0001959"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1124\/pr.56.2.6","article-title":"Anthracyclines: Molecular Advances and Pharmacologic Developments in Antitumor Activity and Cardiotoxicity","volume":"56","author":"Minotti","year":"2004","journal-title":"Pharm. Rev."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00280-019-03827-0","article-title":"Chemotherapy and Cognition: Comprehensive Review on Doxorubicin-Induced Chemobrain","volume":"84","author":"Esmat","year":"2019","journal-title":"Cancer Chemother. Pharm."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1126\/science.1088417","article-title":"Inflammatory Blockade Restores Adult Hippocampal Neurogenesis","volume":"302","author":"Monje","year":"2003","journal-title":"Science"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.bbr.2007.08.004","article-title":"Long-Lasting Suppression of Hippocampal Cell Proliferation and Impaired Cognitive Performance by Methotrexate in the Rat","volume":"186","author":"Seigers","year":"2008","journal-title":"Behav. Brain Res."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.bbr.2009.02.025","article-title":"Methotrexate Decreases Hippocampal Cell Proliferation and Induces Memory Deficits in Rats","volume":"201","author":"Seigers","year":"2009","journal-title":"Behav. Brain Res."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00213-010-2122-2","article-title":"Fluoxetine Reverses the Memory Impairment and Reduction in Proliferation and Survival of Hippocampal Cells Caused by Methotrexate Chemotherapy","volume":"215","author":"Lyons","year":"2011","journal-title":"Psychopharmacology"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"114083","DOI":"10.1016\/j.bcp.2020.114083","article-title":"Neuroprotective Effects of Hesperidin against Methotrexate-Induced Changes in Neurogenesis and Oxidative Stress in the Adult Rat","volume":"178","author":"Welbat","year":"2020","journal-title":"Biochem. Pharmacol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/jbiol69","article-title":"Systemic 5-Fluorouracil Treatment Causes a Syndrome of Delayed Myelin Destruction in the Central Nervous System","volume":"7","author":"Han","year":"2008","journal-title":"J. Biol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"544","DOI":"10.3109\/07357900903405942","article-title":"IGF-1 Partially Restores Chemotherapy-Induced Reductions in Neural Cell Proliferation in Adult C57BL\/6 Mice","volume":"28","author":"Janelsins","year":"2010","journal-title":"Cancer Investig."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Lyons, L., ELBeltagy, M., Bennett, G., and Wigmore, P. (2012). Fluoxetine Counteracts the Cognitive and Cellular Effects of 5-Fluorouracil in the Rat Hippocampus by a Mechanism of Prevention Rather than Recovery. PLoS ONE, 7.","DOI":"10.1371\/journal.pone.0030010"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"117468","DOI":"10.1016\/j.lfs.2020.117468","article-title":"Melatonin Attenuates 5-Fluorouracil-Induced Spatial Memory and Hippocampal Neurogenesis Impairment in Adult Rats","volume":"248","author":"Sirichoat","year":"2020","journal-title":"Life Sci."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/jbiol50","article-title":"CNS Progenitor Cells and Oligodendrocytes Are Targets of Chemotherapeutic Agents in Vitro and in Vivo","volume":"5","author":"Dietrich","year":"2006","journal-title":"J. Biol."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s12640-013-9443-y","article-title":"Cisplatin Inhibits Hippocampal Cell Proliferation and Alters the Expression of Apoptotic Genes","volume":"25","author":"Manohar","year":"2014","journal-title":"Neurotox. Res."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1158\/0008-5472.CAN-16-1817","article-title":"Pifithrin-\u03bc Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function","volume":"77","author":"Chiu","year":"2017","journal-title":"Cancer Res."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.bbr.2015.06.007","article-title":"Doxorubicin and Cyclophosphamide Treatment Produces Anxiety-like Behavior and Spatial Cognition Impairment in Rats: Possible Involvement of Hippocampal Neurogenesis via Brain-Derived Neurotrophic Factor and Cyclin D1 Regulation","volume":"292","author":"Kitamura","year":"2015","journal-title":"Behav. Brain Res."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.bbrc.2013.05.087","article-title":"Compound K Is Able to Ameliorate the Impaired Cognitive Function and Hippocampal Neurogenesis Following Chemotherapy Treatment","volume":"436","author":"Hou","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Garthe, A., Behr, J., and Kempermann, G. (2009). Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies. PLoS ONE, 4.","DOI":"10.1371\/journal.pone.0005464"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1126\/science.1248903","article-title":"Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy","volume":"344","author":"Akers","year":"2014","journal-title":"Science"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.nlm.2018.06.014","article-title":"Inhibiting Constitutive Neurogenesis Compromises Long-Term Social Recognition Memory","volume":"155","author":"Guarnieri","year":"2018","journal-title":"Neurobiol. Learn. Mem."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/ncomms2261","article-title":"Suppression of Adult Neurogenesis Impairs Population Coding of Similar Contexts in Hippocampal CA3 Region","volume":"3","author":"Niibori","year":"2012","journal-title":"Nat. Commun."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.neuropharm.2018.02.013","article-title":"Physical Exercise Prevents Cognitive Impairment by Enhancing Hippocampal Neuroplasticity and Mitochondrial Function in Doxorubicin-Induced Chemobrain","volume":"133","author":"Park","year":"2018","journal-title":"Neuropharmacology"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"11667","DOI":"10.1038\/s41598-017-12054-7","article-title":"The Cancer Chemotherapeutic Agent Paclitaxel (Taxol) Reduces Hippocampal Neurogenesis via down-Regulation of Vesicular Zinc","volume":"7","author":"Lee","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.nlm.2017.08.001","article-title":"The Chemotherapeutic Agent Paclitaxel Selectively Impairs Reversal Learning While Sparing Prior Learning, New Learning and Episodic Memory","volume":"144","author":"Carey","year":"2017","journal-title":"Neurobiol. Learn. Mem."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"e1185","DOI":"10.1038\/tp.2017.149","article-title":"A Novel Preventive Therapy for Paclitaxel-Induced Cognitive Deficits: Preclinical Evidence from C57BL\/6 Mice","volume":"7","author":"Huehnchen","year":"2017","journal-title":"Transl. Psychiatry"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Briones, T.L., and Woods, J. (2011). Chemotherapy-Induced Cognitive Impairment Is Associated with Decreases in Cell Proliferation and Histone Modifications. BMC Neurosci., 12.","DOI":"10.1186\/1471-2202-12-124"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1037\/bne0000155","article-title":"Environmental Enrichment Protects against Cognitive Impairment Following Chemotherapy in an Animal Model","volume":"130","author":"Winocur","year":"2016","journal-title":"Behav. Neurosci."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1007\/s00213-013-3394-0","article-title":"Physical Exercise Prevents Suppression of Hippocampal Neurogenesis and Reduces Cognitive Impairment in Chemotherapy-Treated Rats","volume":"231","author":"Winocur","year":"2014","journal-title":"Psychopharmacology"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.bbr.2014.12.028","article-title":"Memory Loss in Chemotherapy-Treated Rats Is Exacerbated in High-Interference Conditions and Related to Suppression of Hippocampal Neurogenesis","volume":"281","author":"Winocur","year":"2015","journal-title":"Behav. Brain Res."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.neuroscience.2017.10.048","article-title":"Neurobiological Mechanisms of Chemotherapy-Induced Cognitive Impairment in a Transgenic Model of Breast Cancer","volume":"369","author":"Winocur","year":"2018","journal-title":"Neuroscience"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bbr.2016.07.043","article-title":"Long-Lasting Impairments in Adult Neurogenesis, Spatial Learning and Memory from a Standard Chemotherapy Regimen Used to Treat Breast Cancer","volume":"315","author":"Rendeiro","year":"2016","journal-title":"Behav. Brain Res."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Sekeres, M.J., Bradley-Garcia, M., Martinez-Canabal, A., and Winocur, G. (2021). Chemotherapy-Induced Cognitive Impairment and Hippocampal Neurogenesis: A Review of Physiological Mechanisms and Interventions. IJMS, 22.","DOI":"10.3390\/ijms222312697"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.nicl.2017.03.004","article-title":"Subtle Hippocampal Deformities in Breast Cancer Survivors with Reduced Episodic Memory and Self-Reported Cognitive Concerns","volume":"14","author":"Apple","year":"2017","journal-title":"NeuroImage Clin."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/ana.21214","article-title":"Impaired Human Hippocampal Neurogenesis after Treatment for Central Nervous System Malignancies","volume":"62","author":"Monje","year":"2007","journal-title":"Ann. Neurol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/3305","article-title":"Neurogenesis in the Adult Human Hippocampus","volume":"4","author":"Eriksson","year":"1998","journal-title":"Nat. Med."},{"key":"ref_76","doi-asserted-by":"crossref","unstructured":"Knoth, R., Singec, I., Ditter, M., Pantazis, G., Capetian, P., Meyer, R.P., Horvat, V., Volk, B., and Kempermann, G. (2010). Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years. PLoS ONE, 5.","DOI":"10.1371\/journal.pone.0008809"},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/j.cell.2013.05.002","article-title":"Dynamics of Hippocampal Neurogenesis in Adult Humans","volume":"153","author":"Spalding","year":"2013","journal-title":"Cell"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.stem.2018.03.015","article-title":"Human Hippocampal Neurogenesis Persists throughout Aging","volume":"22","author":"Boldrini","year":"2018","journal-title":"Cell Stem. Cell"},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.stem.2018.04.004","article-title":"Human Adult Neurogenesis: Evidence and Remaining Questions","volume":"23","author":"Kempermann","year":"2018","journal-title":"Cell Stem. Cell"},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1634\/theoncologist.2008-0130","article-title":"Clinical Patterns and Biological Correlates of Cognitive Dysfunction Associated with Cancer Therapy","volume":"13","author":"Dietrich","year":"2008","journal-title":"Oncologist"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.bbr.2011.05.012","article-title":"Cognitive Side Effects of Cancer Therapy Demonstrate a Functional Role for Adult Neurogenesis","volume":"227","author":"Monje","year":"2012","journal-title":"Behav. Brain Res."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"e12075","DOI":"10.15252\/emmm.202012075","article-title":"Cellular Mechanisms and Treatments for Chemobrain: Insight from Aging and Neurodegenerative Diseases","volume":"12","author":"Nguyen","year":"2020","journal-title":"EMBO Mol. Med."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/01.wnn.0000208290.57370.a3","article-title":"Patterns of Verbal Memory Performance in Mild Cognitive Impairment, Alzheimer Disease, and Normal Aging","volume":"19","author":"Greenaway","year":"2006","journal-title":"Cogn. Behav. Neurol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1080\/13803390902889606","article-title":"The California Verbal Learning Test and Other Standard Clinical Neuropsychological Tests to Predict Conversion from Mild Memory Impairment to Dementia","volume":"32","author":"Lekeu","year":"2010","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1177\/1073191120929093","article-title":"Comparing the Psychometric Properties of Eight Embedded Performance Validity Tests in the Rey Auditory Verbal Learning Test, Wechsler Memory Scale Logical Memory, and Brief Visuospatial Memory Test\u2013Revised Recognition Trials for Detecting Invalid Neuropsychological Test Performance","volume":"28","author":"Pliskin","year":"2021","journal-title":"Assessment"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s13195-015-0147-9","article-title":"Verbal and Non-Verbal Memory and Hippocampal Volumes in a Memory Clinic Population","volume":"7","author":"Mahmoud","year":"2015","journal-title":"Alzheimer Res. Ther."},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0896-6273(00)80474-2","article-title":"Hemispheric Specialization in Human Dorsal Frontal Cortex and Medial Temporal Lobe for Verbal and Nonverbal Memory Encoding","volume":"20","author":"Kelley","year":"1998","journal-title":"Neuron"},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/pon.1453","article-title":"Cognitive Effects of Hormonal Therapy in Early Stage Breast Cancer Patients: A Prospective Study","volume":"18","author":"Collins","year":"2009","journal-title":"Psycho-Oncology"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1017\/S1355617713001215","article-title":"Persistent Cognitive Changes in Breast Cancer Patients 1 Year Following Completion of Chemotherapy","volume":"20","author":"Collins","year":"2014","journal-title":"J. Int. Neuropsychol. Soc."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"4434","DOI":"10.1200\/JCO.2009.27.0827","article-title":"Longitudinal Assessment of Cognitive Changes Associated With Adjuvant Treatment for Breast Cancer: Impact of Age and Cognitive Reserve","volume":"28","author":"Ahles","year":"2010","journal-title":"JCO"},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Menning, S., de Ruiter, M.B., Veltman, D.J., Boogerd, W., Oldenburg, H.S.A., Reneman, L., and Schagen, S.B. (2017). Changes in Brain Activation in Breast Cancer Patients Depend on Cognitive Domain and Treatment Type. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0171724"},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1016\/j.neuron.2021.04.025","article-title":"No Consolidation without Representation: Correspondence between Neural and Psychological Representations in Recent and Remote Memory","volume":"109","author":"Gilboa","year":"2021","journal-title":"Neuron"},{"key":"ref_93","unstructured":"Tulving, E. (1972). Episodic and Semantic Memory. Organization of Memory, Academic Press."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/nrn2277","article-title":"Where Do You Know What You Know? The Representation of Semantic Knowledge in the Human Brain","volume":"8","author":"Patterson","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neulet.2018.05.006","article-title":"The Hippocampus and Related Neocortical Structures in Memory Transformation","volume":"680","author":"Sekeres","year":"2018","journal-title":"Neurosci. Lett."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/h0080017","article-title":"Memory and Consciousness","volume":"26","author":"Tulving","year":"1985","journal-title":"Can. Psychol. Psychol. Can."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1016\/j.neuropsychologia.2004.10.007","article-title":"The Case of K.C.: Contributions of a Memory-Impaired Person to Memory Theory","volume":"43","author":"Rosenbaum","year":"2005","journal-title":"Neuropsychologia"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.psych.53.100901.135114","article-title":"Episodic Memory: From Mind to Brain","volume":"53","author":"Tulving","year":"2002","journal-title":"Annu. Rev. Psychol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.neuropsychologia.2005.01.001","article-title":"Medial Temporal Lobe Structures Are Needed to Re-Experience Remote Autobiographical Memories: Evidence from H.M. and W.R","volume":"43","author":"Steinvorth","year":"2005","journal-title":"Neuropsychologia"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1016\/j.neuropsychologia.2009.01.032","article-title":"Determinants of Autobiographical Memory in Patients with Unilateral Temporal Lobe Epilepsy or Excisions","volume":"47","author":"Moscovitch","year":"2009","journal-title":"Neuropsychologia"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1037\/0096-3445.120.4.395","article-title":"On the Very Long-Term Retention of Knowledge Acquired through Formal Education: Twelve Years of Cognitive Psychology","volume":"120","author":"Conway","year":"1991","journal-title":"J. Exp. Psychol. Gen."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.3758\/BF03194319","article-title":"Tunnel Memories for Autobiographical Events: Central Details Are Remembered More Frequently from Shocking than from Happy Experiences","volume":"30","author":"Berntsen","year":"2002","journal-title":"Mem. Cogn."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1176\/appi.ajp.161.12.2263","article-title":"Hippocampal Volume and First Major Depressive Episode After Cancer Diagnosis in Breast Cancer Survivors","volume":"161","author":"Inagaki","year":"2004","journal-title":"AJP"},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s10549-005-1412-6","article-title":"No Adverse Effects of Adjuvant Chemotherapy on Hippocampal Volumein Japanese Breast Cancer Survivors","volume":"92","author":"Yoshikawa","year":"2005","journal-title":"Breast Cancer Res. Treat"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"3866","DOI":"10.1200\/JCO.2007.10.8639","article-title":"Brain Structure and Function Differences in Monozygotic Twins: Possible Effects of Breast Cancer Chemotherapy","volume":"25","author":"Ferguson","year":"2007","journal-title":"JCO"},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/cncr.22368","article-title":"Smaller Regional Volumes of Brain Gray and White Matter Demonstrated in Breast Cancer Survivors Exposed to Adjuvant Chemotherapy","volume":"109","author":"Inagaki","year":"2007","journal-title":"Cancer"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/s10549-010-1088-4","article-title":"Gray Matter Reduction Associated with Systemic Chemotherapy for Breast Cancer: A Prospective MRI Study","volume":"123","author":"McDonald","year":"2010","journal-title":"Breast Cancer Res. Treat"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s10549-012-2385-x","article-title":"Alterations in Brain Structure and Function in Breast Cancer Survivors: Effect of Post-Chemotherapy Interval and Relation to Oxidative DNA Damage","volume":"137","author":"Conroy","year":"2013","journal-title":"Breast Cancer Res. Treat"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"S109","DOI":"10.1016\/j.bbi.2012.05.017","article-title":"Reduced Hippocampal Volume and Verbal Memory Performance Associated with Interleukin-6 and Tumor Necrosis Factor-Alpha Levels in Chemotherapy-Treated Breast Cancer Survivors","volume":"30","author":"Kesler","year":"2013","journal-title":"Brain Behav. Immun."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1186\/2193-1801-3-444","article-title":"A Prospective Study of Grey Matter and Cognitive Function Alterations in Chemotherapy-Treated Breast Cancer Patients","volume":"3","author":"Lepage","year":"2014","journal-title":"SpringerPlus"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"6665","DOI":"10.1158\/1078-0432.CCR-09-1227","article-title":"Regional Brain Activation during Verbal Declarative Memory in Metastatic Breast Cancer","volume":"15","author":"Kesler","year":"2009","journal-title":"Clin. Cancer Res."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1007\/s11682-012-9213-0","article-title":"Differences in Verbal Memory Retrieval in Breast Cancer Chemotherapy Patients Compared to Healthy Controls: A Prospective FMRI Study","volume":"7","author":"Scherling","year":"2013","journal-title":"Brain Imaging Behav."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.nicl.2018.07.010","article-title":"Hippocampal Functional Connectivity Is Related to Self-Reported Cognitive Concerns in Breast Cancer Patients Undergoing Adjuvant Therapy","volume":"20","author":"Apple","year":"2018","journal-title":"NeuroImage Clin."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.nbd.2012.07.009","article-title":"Altered Resting State Functional Brain Network Topology in Chemotherapy-Treated Breast Cancer Survivors","volume":"48","author":"Bruno","year":"2012","journal-title":"Neurobiol. Dis."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"e12553","DOI":"10.1111\/ecc.12553","article-title":"Impairment of the Executive Function in Breast Cancer Patients Receiving Chemotherapy Treatment: A Functional MRI Study","volume":"26","author":"Tao","year":"2017","journal-title":"Eur. J. Cancer Care"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"45135","DOI":"10.1038\/srep45135","article-title":"Altered Resting-State Hippocampal Functional Networks Associated with Chemotherapy-Induced Prospective Memory Impairment in Breast Cancer Survivors","volume":"7","author":"Cheng","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_117","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.pnpbp.2019.03.008","article-title":"Altered Network Homogeneity of the Default-Mode Network in Drug-Naive Obsessive\u2212compulsive Disorder","volume":"93","author":"Chen","year":"2019","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1007\/s11682-019-00067-x","article-title":"Postchemotherapy Hippocampal Functional Connectivity Patterns in Patients with Breast Cancer: A Longitudinal Resting State Functional MR Imaging Study","volume":"14","author":"Feng","year":"2020","journal-title":"Brain Imaging Behav."},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1186\/s40644-020-00355-6","article-title":"Network-Level Functional Connectivity Alterations in Chemotherapy Treated Breast Cancer Patients: A Longitudinal Resting State Functional MRI Study","volume":"20","author":"Feng","year":"2020","journal-title":"Cancer Imaging"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"16982","DOI":"10.1523\/JNEUROSCI.2475-12.2012","article-title":"Detecting Representations of Recent and Remote Autobiographical Memories in VmPFC and Hippocampus","volume":"32","author":"Bonnici","year":"2012","journal-title":"J. Neurosci."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.neuropsychologia.2017.05.014","article-title":"Two Years Later\u2013Revisiting Autobiographical Memory Representations in VmPFC and Hippocampus","volume":"110","author":"Bonnici","year":"2018","journal-title":"Neuropsychologia"},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neubiorev.2019.09.003","article-title":"Looking into Recent and Remote Past: Meta-Analytic Evidence for Cortical Re-Organization of Episodic Autobiographical Memories","volume":"107","author":"Boccia","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"17501","DOI":"10.1073\/pnas.0607207103","article-title":"Ablation of Hippocampal Neurogenesis Impairs Contextual Fear Conditioning and Synaptic Plasticity in the Dentate Gyrus","volume":"103","author":"Saxe","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1037\/a0020081","article-title":"Arrest of Adult Hippocampal Neurogenesis in Mice Impairs Single- but Not Multiple-Trial Contextual Fear Conditioning","volume":"124","author":"Drew","year":"2010","journal-title":"Behav. Neurosci."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1002\/hipo.23330","article-title":"Reduced Anterior Hippocampal and Ventromedial Prefrontal Activity When Repeatedly Retrieving Autobiographical Memories","volume":"31","author":"Gurguryan","year":"2021","journal-title":"Hippocampus"},{"key":"ref_126","doi-asserted-by":"crossref","unstructured":"Mccormick, C., St-Laurent, M., Ty, A., Valiante, T., and Mcandrews, M. (2013). Functional and Effective Hippocampal-Neocortical Connectivity During Construction and Elaboration of Autobiographical Memory Retrieval. Cereb. Cortex, 25.","DOI":"10.1093\/cercor\/bht324"},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1002\/hipo.22249","article-title":"The Perceptual Richness of Complex Memory Episodes Is Compromised by Medial Temporal Lobe Damage","volume":"24","author":"Moscovitch","year":"2014","journal-title":"Hippocampus"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1162\/jocn.2008.20105","article-title":"Patterns of Autobiographical Memory Loss in Medial-Temporal Lobe Amnesic Patients","volume":"20","author":"Rosenbaum","year":"2008","journal-title":"J. Cogn. Neurosci."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.jpsychores.2004.01.009","article-title":"Autobiographical Memories in Patients Treated for Breast Cancer","volume":"57","author":"Liss","year":"2004","journal-title":"J. Psychosom. Res."},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1037\/0033-295X.107.2.261","article-title":"The Construction of Autobiographical Memories in the Self-Memory System","volume":"107","author":"Conway","year":"2000","journal-title":"Psychol. Rev."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1037\/0021-843X.95.2.144","article-title":"Autobiographical Memory in Suicide Attempters","volume":"95","author":"Williams","year":"1986","journal-title":"J. Abnorm. Psychol."},{"key":"ref_132","doi-asserted-by":"crossref","unstructured":"Bergouignan, L., Lefranc, J.P., Chupin, M., Morel, N., Spano, J.P., and Fossati, P. (2011). Breast Cancer Affects Both the Hippocampus Volume and the Episodic Autobiographical Memory Retrieval. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0025349"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/hipo.23009","article-title":"Changes in Patterns of Neural Activity Underlie a Time-Dependent Transformation of Memory in Rats and Humans","volume":"28","author":"Sekeres","year":"2018","journal-title":"Hippocampus"},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/hipo.23260","article-title":"Reminders Activate the Prefrontal-medial Temporal Cortex and Attenuate Forgetting of Event Memory","volume":"31","author":"Sekeres","year":"2021","journal-title":"Hippocampus"},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1080\/01688638908400928","article-title":"The Autobiographical Memory Interview: A New Assessment of Autobiographical and Personal Semantic Memory in Amnesic Patients","volume":"11","author":"Kopelman","year":"1989","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1037\/0882-7974.17.4.677","article-title":"Aging and Autobiographical Memory: Dissociating Episodic from Semantic Retrieval","volume":"17","author":"Levine","year":"2002","journal-title":"Psychol. Aging"},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.neuropsychologia.2006.10.016","article-title":"Remembering the Past and Imagining the Future: Common and Distinct Neural Substrates during Event Construction and Elaboration","volume":"45","author":"Addis","year":"2007","journal-title":"Neuropsychologia"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"13480","DOI":"10.1073\/pnas.1617025113","article-title":"Learning and Remembering Real-World Events after Medial Temporal Lobe Damage","volume":"113","author":"Dede","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"e41836","DOI":"10.7554\/eLife.41836","article-title":"Human Hippocampal CA3 Damage Disrupts Both Recent and Remote Episodic Memories","volume":"9","author":"Miller","year":"2020","journal-title":"eLife"},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1024\/1662-9647\/a000219","article-title":"Interindividual Differences in Cognitive Functioning Are Associated with Autobiographical Memory Retrieval Specificity in Older Adults","volume":"33","author":"Peters","year":"2020","journal-title":"GeroPsych"},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"422","DOI":"10.3758\/s13421-020-01098-2","article-title":"Searching for the Past: Exploring the Dynamics of Direct and Generative Autobiographical Memory Reconstruction among Young and Cognitively Normal Older Adults","volume":"49","author":"Wank","year":"2021","journal-title":"Mem. Cogn."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"8251","DOI":"10.1523\/JNEUROSCI.1056-18.2018","article-title":"Impaired Recent, but Preserved Remote, Autobiographical Memory in Pediatric Brain Tumor Patients","volume":"38","author":"Sekeres","year":"2018","journal-title":"J. Neurosci."},{"key":"ref_143","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1101\/lm.039057.115","article-title":"Recovering and Preventing Loss of Detailed Memory: Differential Rates of Forgetting for Detail Types in Episodic Memory","volume":"23","author":"Sekeres","year":"2016","journal-title":"Learn. Mem."},{"key":"ref_144","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1176\/appi.ajp.159.12.2087","article-title":"Relationship Between Distressing Cancer-Related Recollections and Hippocampal Volume in Cancer Survivors","volume":"159","author":"Nakano","year":"2002","journal-title":"AJP"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1200\/JCO.2011.36.8571","article-title":"Longitudinal Assessment of Chemotherapy-Induced Structural Changes in Cerebral White Matter and Its Correlation With Impaired Cognitive Functioning","volume":"30","author":"Deprez","year":"2012","journal-title":"JCO"},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1200\/JCO.2011.38.5674","article-title":"Alterations in Brain Activation During Working Memory Processing Associated With Breast Cancer and Treatment: A Prospective Functional Magnetic Resonance Imaging Study","volume":"30","author":"McDonald","year":"2012","journal-title":"J. Clin. Oncol."},{"key":"ref_147","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.tics.2013.03.005","article-title":"Long-Axis Specialization of the Human Hippocampus","volume":"17","author":"Poppenk","year":"2013","journal-title":"Trends Cogn. Sci."},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.neuron.2009.11.031","article-title":"Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?","volume":"65","author":"Fanselow","year":"2010","journal-title":"Neuron"},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev-psych-113011-143733","article-title":"Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation","volume":"67","author":"Moscovitch","year":"2016","journal-title":"Annu. Rev. Psychol."},{"key":"ref_150","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.neuron.2011.10.014","article-title":"A Hippocampal Marker of Recollection Memory Ability among Healthy Young Adults: Contributions of Posterior and Anterior Segments","volume":"72","author":"Poppenk","year":"2011","journal-title":"Neuron"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cobeha.2017.07.016","article-title":"Details, Gist and Schema: Hippocampal\u2013Neocortical Interactions Underlying Recent and Remote Episodic and Spatial Memory","volume":"17","author":"Robin","year":"2017","journal-title":"Curr. Opin. Behav. Sci."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.neuropsychologia.2017.09.020","article-title":"Dynamic Changes in Large-Scale Functional Network Organization during Autobiographical Memory Retrieval","volume":"110","author":"Inman","year":"2018","journal-title":"Neuropsychologia"},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/mono.12033","article-title":"III. NIH Toolbox Cognition Battery (CB): Measuring Episodic Memory: NIH Toolbox Cognition Battery (CB)","volume":"78","author":"Bauer","year":"2013","journal-title":"Monogr. Soc. Res. Child"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1200\/jco.2015.33.15_suppl.1024","article-title":"Hippocampal Memory Impairment in Breast Cancer Survivors after Chemotherapy Measurement Using Covert Testing","volume":"33","author":"Ryals","year":"2015","journal-title":"JCO"},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1037\/0278-7393.13.3.501","article-title":"Implicit Memory: History and Current Status","volume":"13","author":"Schacter","year":"1987","journal-title":"J. Exp. Psychol. Learn. Mem. Cogn."},{"key":"ref_156","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1038\/33396","article-title":"Dissociation of the Neural Correlates of Implicit and Explicit Memory","volume":"392","author":"Rugg","year":"1998","journal-title":"Nature"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0896-6273(00)80456-0","article-title":"Functional-Anatomic Correlates of Object Priming in Humans Revealed by Rapid Presentation Event-Related FMRI","volume":"20","author":"Buckner","year":"1998","journal-title":"Neuron"},{"key":"ref_158","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A Default Mode of Brain Function","volume":"98","author":"Raichle","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1440.011","article-title":"The Brain\u2019s Default Network: Anatomy, Function, and Relevance to Disease","volume":"1124","author":"Buckner","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1162\/jocn.2008.21029","article-title":"The Common Neural Basis of Autobiographical Memory, Prospection, Navigation, Theory of Mind, and the Default Mode: A Quantitative Meta-Analysis","volume":"21","author":"Spreng","year":"2009","journal-title":"J. Cogn. Neurosci."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.tics.2006.11.004","article-title":"Self-Projection and the Brain","volume":"11","author":"Buckner","year":"2007","journal-title":"Trends Cogn. Sci."},{"key":"ref_162","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.neuron.2010.02.005","article-title":"Functional-Anatomic Fractionation of the Brain\u2019s Default Network","volume":"65","author":"Reidler","year":"2010","journal-title":"Neuron"},{"key":"ref_163","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1162\/jocn.2009.21282","article-title":"Patterns of Brain Activity Supporting Autobiographical Memory, Prospection, and Theory of Mind, and Their Relationship to the Default Mode Network","volume":"22","author":"Spreng","year":"2010","journal-title":"J. Cogn. Neurosci."},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/S1053-8119(03)00179-4","article-title":"Thinking of the Future and Past: The Roles of the Frontal Pole and the Medial Temporal Lobes","volume":"19","author":"Okuda","year":"2003","journal-title":"Neuroimage"},{"key":"ref_165","first-page":"173","article-title":"The Hippocampus and Imagining the Future: Where Do We Stand?","volume":"5","author":"Addis","year":"2011","journal-title":"Front. Hum. Neurosci."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/nrn2213","article-title":"Remembering the Past to Imagine the Future: The Prospective Brain","volume":"8","author":"Schacter","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1098\/rstb.2008.0296","article-title":"The Construction System of the Brain","volume":"364","author":"Hassabis","year":"2009","journal-title":"Philos. Trans. R. Soc. B Biol. Sci."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/445027a","article-title":"The Ghosts of Past and Future","volume":"445","author":"Schacter","year":"2007","journal-title":"Nature"},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1037\/a0029869","article-title":"Adaptive Constructive Processes and the Future of Memory","volume":"67","author":"Schacter","year":"2012","journal-title":"Am. Psychol."},{"key":"ref_170","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1037\/0894-4105.13.1.103","article-title":"Prospective Memory: A Neuropsychological Study","volume":"13","author":"McDaniel","year":"1999","journal-title":"Neuropsychology"},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0028-3932(00)00149-4","article-title":"Brain Regions Involved in Prospective Memory as Determined by Positron Emission Tomography","volume":"39","author":"Burgess","year":"2001","journal-title":"Neuropsychologia"},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.neubiorev.2015.02.007","article-title":"Neural Bases of Prospective Memory: A Meta-Analysis and the \u201cAttention to Delayed Intention\u201d (AtoDI) Model","volume":"52","author":"Cona","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1016\/j.neuropsychologia.2010.12.029","article-title":"The Neuropsychology of Prospective Memory in Normal Aging: A Componential Approach","volume":"49","author":"McDaniel","year":"2011","journal-title":"Neuropsychologia"},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1002\/pon.3291","article-title":"Chemotherapy-Induced Prospective Memory Impairment in Patients with Breast Cancer: Chemotherapy-Induced PM Impairment in Breast Cancer Patients","volume":"22","author":"Cheng","year":"2013","journal-title":"Psycho-Oncology"},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/07347332.2016.1181133","article-title":"Prospective Memory Impairment in Chemotherapy-Exposed Early Breast Cancer Survivors: Preliminary Evidence from a Clinical Test","volume":"34","author":"Bedard","year":"2016","journal-title":"J. Psychosoc. Oncol."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S1364-6613(00)01804-0","article-title":"Episodic Future Thinking","volume":"5","author":"Atance","year":"2001","journal-title":"Trends Cogn. Sci."},{"key":"ref_177","doi-asserted-by":"crossref","unstructured":"Roediger, H.L., Nairne, J.S., Neath, I., and Surprenant, A.M. (2001). Origin of Autonoesis in Episodic Memory. The Nature of Remembering: Essays in Honor of Robert G. Crowder, American Psychological Association.","DOI":"10.1037\/10394-000"},{"key":"ref_178","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.cobeha.2017.06.002","article-title":"Episodic Future Thinking: Mechanisms and Functions","volume":"17","author":"Schacter","year":"2017","journal-title":"Curr. Opin. Behav. Sci."},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1002\/hipo.20226","article-title":"Hippocampal Contributions to Recollection in Retrograde and Anterograde Amnesia","volume":"16","author":"Gilboa","year":"2006","journal-title":"Hippocampus"},{"key":"ref_180","doi-asserted-by":"crossref","first-page":"10262","DOI":"10.1523\/JNEUROSCI.1145-11.2011","article-title":"Medial Temporal Lobe Damage Causes Deficits in Episodic Memory and Episodic Future Thinking Not Attributable to Deficits in Narrative Construction","volume":"31","author":"Race","year":"2011","journal-title":"J. Neurosci."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.neuropsychologia.2017.08.007","article-title":"Episodic Future Thinking and Future-Based Decision-Making in a Case of Retrograde Amnesia","volume":"110","author":"Benuzzi","year":"2018","journal-title":"Neuropsychologia"},{"key":"ref_182","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1523\/JNEUROSCI.1812-17.2018","article-title":"Mind-Wandering in People with Hippocampal Damage","volume":"38","author":"McCormick","year":"2018","journal-title":"J. Neurosci."},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"e00643","DOI":"10.1002\/brb3.643","article-title":"Disrupted Brain Network Functional Dynamics and Hyper-Correlation of Structural and Functional Connectome Topology in Patients with Breast Cancer Prior to Treatment","volume":"7","author":"Kesler","year":"2017","journal-title":"Brain Behav."},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"11600","DOI":"10.1073\/pnas.1214551110","article-title":"Default Mode Network Connectivity Distinguishes Chemotherapy-Treated Breast Cancer Survivors from Controls","volume":"110","author":"Kesler","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_185","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.tics.2006.07.005","article-title":"Beyond Mind-Reading: Multi-Voxel Pattern Analysis of FMRI Data","volume":"10","author":"Norman","year":"2006","journal-title":"Trends Cogn. Sci."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.neurobiolaging.2014.03.036","article-title":"Default Mode Network as a Potential Biomarker of Chemotherapy-Related Brain Injury","volume":"35","author":"Kesler","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.acra.2016.05.014","article-title":"Executive Function Alternations of Breast Cancer Patients After Chemotherapy","volume":"23","author":"Wang","year":"2016","journal-title":"Acad. Radiol."},{"key":"ref_188","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1007\/s00234-016-1708-8","article-title":"Functional Connectivity Change of Brain Default Mode Network in Breast Cancer Patients after Chemotherapy","volume":"58","author":"Miao","year":"2016","journal-title":"Neuroradiology"},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/s11764-020-00945-0","article-title":"Mindfulness-Based Stress Reduction Alters Brain Activity for Breast Cancer Survivors with Chronic Neuropathic Pain: Preliminary Evidence from Resting-State FMRI","volume":"15","author":"Smith","year":"2021","journal-title":"J. Cancer Surviv."},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.nicl.2015.02.005","article-title":"Multimodal MRI and Cognitive Function in Patients with Breast Cancer Prior to Adjuvant Treatment\u2014The Role of Fatigue","volume":"7","author":"Menning","year":"2015","journal-title":"NeuroImage Clin."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/13803395.2012.666227","article-title":"Prechemotherapy Differences in Response Inhibition in Breast Cancer Patients Compared to Controls: A Functional Magnetic Resonance Imaging Study","volume":"34","author":"Scherling","year":"2012","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1080\/13803390903032537","article-title":"Prechemotherapy Alterations in Brain Function in Women with Breast Cancer","volume":"32","author":"Cimprich","year":"2010","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s11682-017-9728-5","article-title":"A Mechanistic Cohort Study Evaluating Cognitive Impairment in Women Treated for Breast Cancer","volume":"13","author":"Vardy","year":"2019","journal-title":"Brain Imaging Behav."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"8920","DOI":"10.1523\/JNEUROSCI.2587-10.2011","article-title":"Subjective Sense of Memory Strength and the Objective Amount of Information Accurately Remembered Are Related to Distinct Neural Correlates at Encoding","volume":"31","author":"Qin","year":"2011","journal-title":"J. Neurosci."},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"644","DOI":"10.3758\/s13415-015-0352-9","article-title":"Age-Related Differences in the Neural Basis of the Subjective Vividness of Memories: Evidence from Multivoxel Pattern Classification","volume":"15","author":"Johnson","year":"2015","journal-title":"Cogn. Affect. Behav. Neurosci."},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1126\/science.205.4404.386","article-title":"Eyewitness Reliability","volume":"205","author":"Loftus","year":"1979","journal-title":"Science"},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1002\/pon.964","article-title":"Cognitive Impairment Associated with Adjuvant Therapy in Breast Cancer","volume":"15","author":"Bender","year":"2006","journal-title":"Psycho-Oncology"},{"key":"ref_198","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/ane.12038","article-title":"Subjective Memory Complaints in Elders: Depression, Anxiety, or Cognitive Decline?","volume":"127","author":"Balash","year":"2013","journal-title":"Acta Neurol. Scand."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/pon.3654","article-title":"A Meta-analysis of Prevalence Rates and Moderating Factors for Cancer-related Post-traumatic Stress Disorder","volume":"24","author":"Abbey","year":"2015","journal-title":"Psycho-Oncology"},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/pon.5055","article-title":"Interventions for the Treatment of Cancer-related Traumatic Stress Symptoms: A Systematic Review of the Literature","volume":"28","author":"Dimitrov","year":"2019","journal-title":"Psycho-Oncology"},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"607514","DOI":"10.3389\/fpsyg.2020.607514","article-title":"Injured Self: Autobiographical Memory, Self-Concept, and Mental Health Risk in Breast Cancer Survivors","volume":"11","author":"Sebri","year":"2020","journal-title":"Front. Psychol."},{"key":"ref_202","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.jml.2005.08.005","article-title":"Memory and the Self\u2606","volume":"53","author":"Conway","year":"2005","journal-title":"J. Mem. Lang."},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.concog.2015.04.016","article-title":"Emotional Specificities of Autobiographical Memory after Breast Cancer Diagnosis","volume":"35","author":"Morel","year":"2015","journal-title":"Conscious. Cogn."}],"container-title":["Cancers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/19\/4752\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:41:48Z","timestamp":1760143308000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6694\/14\/19\/4752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,29]]},"references-count":203,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2022,10]]}},"alternative-id":["cancers14194752"],"URL":"https:\/\/doi.org\/10.3390\/cancers14194752","relation":{},"ISSN":["2072-6694"],"issn-type":[{"value":"2072-6694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,29]]}}}