{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T12:41:02Z","timestamp":1762087262615,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T00:00:00Z","timestamp":1681171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>(1) Background: Salvation surgery for small-cell lung cancer (SCLC) is exceptionally performed, and only a few cases are published. (2) Methods: There are 6 publications that present 17 cases of salvation surgery for SCLC\u2014the salvation surgery was performed in the context of modern clearly established protocols for SCLC and after including SCLC in the TNM (tumor, node, metastasis) staging in 2010. (3) Results: After a median follow-up of 29 months, the estimated overall survival (OS) was 86 months. The median estimated 2-year survival was 92%, and the median estimated 5-year survival was 66%. (4) Conclusion: Salvage surgery for SCLC is a relatively new and extremely uncommon concept and represents an alternative to second-line chemotherapy. It is valuable because it may offer a reasonable treatment for selected patients, good local control, and a favorable survival outcome.<\/jats:p>","DOI":"10.3390\/cancers15082241","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T01:35:08Z","timestamp":1681263308000},"page":"2241","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Salvage Surgery for Small-Cell Lung Cancer\u2014A Literature Review"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6556-3734","authenticated-orcid":false,"given":"Natalia","family":"Motas","sequence":"first","affiliation":[{"name":"Discipline of Thoracic Surgery, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Thoracic Surgery, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology, 022328 Bucharest, Romania"},{"name":"Department of Thoracic Surgery, Oncology Hospital Memorial, 013812 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Manolache","sequence":"additional","affiliation":[{"name":"Discipline of Thoracic Surgery, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Thoracic Surgery, Oncology Hospital Memorial, 013812 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4459-7721","authenticated-orcid":false,"given":"Marco","family":"Scarci","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Imperial College NHS Healthcare, Hammersmith Hospital Du Cane Road, London W12 0HS, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Nimigean","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Faculty of Dentistry, \u201cCarol Davila\u201d University of Medicine and Pharmacy in Bucharest, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanda Roxana","family":"Nimigean","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation, Faculty of Dentistry, \u201cCarol Davila\u201d University of Medicine and Pharmacy in Bucharest, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurentiu","family":"Simion","sequence":"additional","affiliation":[{"name":"Discipline of General and Oncological Surgery, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of General and Oncologic Surgery, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madalina Cristiana","family":"Mizea","sequence":"additional","affiliation":[{"name":"Discipline of Thoracic Surgery, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Thoracic Surgery, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9566-7067","authenticated-orcid":false,"given":"Oana Gabriela","family":"Trifanescu","sequence":"additional","affiliation":[{"name":"Discipline of Oncology, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Radiotherapy, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8093-1750","authenticated-orcid":false,"given":"Bianca","family":"Galateanu","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Bucharest, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4293-0428","authenticated-orcid":false,"given":"Mirela","family":"Gherghe","sequence":"additional","affiliation":[{"name":"Discipline of Nuclear Medicine, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology and University Emergency Military Hospital \u201cDr. Carol Davila\u201d, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina Mirela","family":"Capsa","sequence":"additional","affiliation":[{"name":"Department of Radiology \u201cProf. Dr. Alexandru Trestioreanu\u201d, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Gonzalez-Rivas","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Oncology Hospital Memorial, 013812 Bucharest, Romania"},{"name":"Department of Thoracic Surgery and Minimally Invasive Thoracic Surgery Unit (UCTMI), Coru\u00f1a University Hospital, 15008 Coru\u00f1a, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihnea Dan","family":"Davidescu","sequence":"additional","affiliation":[{"name":"Discipline of Thoracic Surgery, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 022328 Bucharest, Romania"},{"name":"Department of Thoracic Surgery, \u201cProf. Dr. Al. Trestioreanu\u201d Institute of Oncology, 022328 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,4,11]]},"reference":[{"key":"ref_1","unstructured":"LoCicero, J., Feins, R.H., Colson, Y.L., and Rocco, G. (2019). Shields\u2019 General Thoracic Surgery, Wolters Kluwer. [8th ed.]."},{"key":"ref_2","unstructured":"(2023, March 06). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines\u00ae): Small Cell Lung Cancer. Version 2.2022\u201424 November 2021. 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