{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T03:44:49Z","timestamp":1789962289455,"version":"4.0.1"},"reference-count":94,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Solitary fibrous tumors of the pleura (pSFT) are a relatively rare neoplasms that can arise from either visceral or parietal pleura and may have different aggressive biological behaviors. Surgery is well known to be the cornerstone of the treatment for pSFT. We reviewed the existing literature, focusing on the role of surgery in the management and treatment of pSFT. All English-written literature has been reviewed, focusing on those reporting on the perioperative management and postoperative outcomes. Surgery for pSFT is feasible and safe in all experiences reported in the literature, but surgical approaches and techniques may vary according to the tumor dimensions, localization, and surgeons\u2019 skills. Long-term outcomes are good, with a 10-year overall survival rate of more than 70% in most of the reported experiences; on the other hand, recurrence may happen in up to 17% of cases, which occurs mainly in the first two years after surgery, but case reports suggest the need for a longer follow-up to assess the risk of late recurrence. Malignant histology and dimensions are the most recognized risk factors for recurrence. Recurrence might be operated on in select patients. Surgery is the treatment of choice in pSFT, but a radical resection and a careful postoperative follow-up should be carried out.<\/jats:p>","DOI":"10.3390\/cancers15164166","type":"journal-article","created":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T09:13:44Z","timestamp":1692350024000},"page":"4166","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Surgery for Solitary Fibrous Tumors of the Pleura: A Review of the Available Evidence"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-0099","authenticated-orcid":false,"given":"Pietro","family":"Bertoglio","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40100 Bologna, Italy"},{"name":"Alma Mater Studiorum, University of Bologna, 40064 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Querzoli","sequence":"additional","affiliation":[{"name":"Pathology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40100 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kestenholz","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cantonal Hospital of Lucerne, 6000 Lucerne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4459-7721","authenticated-orcid":false,"given":"Marco","family":"Scarci","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Imperial College Healthcare NHS Trust, London W2 1NY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilina","family":"La Porta","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40100 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piergiorgio","family":"Solli","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40100 Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3595-7307","authenticated-orcid":false,"given":"Fabrizio","family":"Minervini","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Cantonal Hospital of Lucerne, 6000 Lucerne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"De Pinieux, G., Karanian, M., Le Loarer, F., Le Guellec, S., Chabaud, S., Terrier, P., Bouvier, C., Batistella, M., Neuville, A., and Robin, Y.M. (2021). Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network. PLoS ONE, 16.","DOI":"10.1371\/journal.pone.0246958"},{"key":"ref_2","unstructured":"Demicco, E.G., Fritchie, K.J., and Han, A. (2020). Who Classification of Tumours Soft Tissue and Bone Tumours, IARC Press. [5th ed.]."},{"key":"ref_3","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.athoracsur.2004.07.013","article-title":"Solitary fibrous tumors of the pleura: Surgical outcome and clinical course","volume":"79","author":"Sung","year":"2005","journal-title":"Ann. Thorac. Surg."},{"key":"ref_4","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1097\/00000478-198908000-00003","article-title":"Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases","volume":"13","author":"England","year":"1989","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_5","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1002\/cncr.10328","article-title":"Clinicopathologic correlates of solitary fibrous tumors","volume":"94","author":"Gold","year":"2002","journal-title":"Cancer"},{"key":"ref_6","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1038\/modpathol.2017.54","article-title":"Risk assessment in solitary fibrous tumors: Validation and refinement of a risk stratification model","volume":"30","author":"Demicco","year":"2017","journal-title":"Mod. Pathol."},{"key":"ref_7","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1007\/s00401-013-1117-6","article-title":"Meningeal hemangiopericytoma and solitary fibrous tumors carry the nab2-stat6 fusion and can be diagnosed by nuclear expression of stat6 protein","volume":"125","author":"Schweizer","year":"2013","journal-title":"Acta Neuropathol."},{"key":"ref_8","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1038\/ng.2509","article-title":"Identification of recurrent nab2-stat6 gene fusions in solitary fibrous tumor by integrative sequencing","volume":"45","author":"Robinson","year":"2013","journal-title":"Nat. Genet."},{"key":"ref_9","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/ng.2522","article-title":"Whole-exome sequencing identifies a recurrent nab2-stat6 fusion in solitary fibrous tumors","volume":"45","author":"Chmielecki","year":"2013","journal-title":"Nat. Genet."},{"key":"ref_10","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1016\/j.ajpath.2013.12.016","article-title":"Solitary fibrous tumors\/hemangiopericytomas with different variants of the nab2-stat6 gene fusion are characterized by specific histomorphology and distinct clinicopathological features","volume":"184","author":"Geddert","year":"2014","journal-title":"Am. J. Pathol."},{"key":"ref_11","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1002\/cam4.572","article-title":"The clinicopathological significance of nab2-stat6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors","volume":"5","author":"Huang","year":"2016","journal-title":"Cancer Med."},{"key":"ref_12","doi-asserted-by":"publisher","first-page":"1324","DOI":"10.1038\/modpathol.2015.90","article-title":"Nab2-stat6 fusion types account for clinicopathological variations in solitary fibrous tumors","volume":"28","author":"Tai","year":"2015","journal-title":"Mod. Pathol."},{"key":"ref_13","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1038\/modpathol.2016.126","article-title":"Tert promoter mutations and prognosis in solitary fibrous tumor","volume":"29","author":"Bahrami","year":"2016","journal-title":"Mod. Pathol."},{"key":"ref_14","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.humpath.2014.11.018","article-title":"Distinct clinicopathological features of nab2-stat6 fusion gene variants in solitary fibrous tumor with emphasis on the acquisition of highly malignant potential","volume":"46","author":"Akaike","year":"2015","journal-title":"Hum. Pathol."},{"key":"ref_15","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1007\/s00428-019-02660-3","article-title":"Solitary fibrous tumor: A case series identifying pathological adverse factors-implications for risk stratification and classification","volume":"476","author":"Machado","year":"2020","journal-title":"Virchows Arch."},{"key":"ref_16","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1111\/his.13703","article-title":"Tert promoter mutations in solitary fibrous tumour","volume":"73","author":"Demicco","year":"2018","journal-title":"Histopathology"},{"key":"ref_17","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/S0003-4975(01)03374-4","article-title":"Solitary fibrous tumors of the pleura","volume":"74","author":"Fischer","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ricciardi, S., Giovanniello, D., Carbone, L., Carleo, F., Di Martino, M., Jaus, M.O., Mantovani, S., Treggiari, S., Tornese, A., and Cardillo, G. (2023). Malignant solitary fibrous tumours of the pleura are not all the same: Analysis of long-term outcomes and evaluation of risk stratification models in a large single-centre series. J. Clin. Med., 12.","DOI":"10.3390\/jcm12030966"},{"key":"ref_19","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1016\/j.jtho.2018.05.040","article-title":"Comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor","volume":"13","author":"Reisenauer","year":"2018","journal-title":"J. Thorac. Oncol."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1097\/PAS.0b013e31817a8a89","article-title":"Pleuro-pulmonary solitary fibrous tumors: A clinicopathologic, immunohistochemical, and molecular study of 88 cases confirming the prognostic value of de perrot staging system and p53 expression, and evaluating the role of c-kit, braf, pdgfrs (alpha\/beta), c-met, and egfr","volume":"32","author":"Schirosi","year":"2008","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_21","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1093\/ejcts\/ezs629","article-title":"Risk factor analysis for the recurrence of resected solitary fibrous tumours of the pleura: A 33-year experience and proposal for a scoring system","volume":"44","author":"Tapias","year":"2013","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_22","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1378\/chest.14-1180","article-title":"Validation of a scoring system to predict recurrence of resected solitary fibrous tumors of the pleura","volume":"147","author":"Tapias","year":"2015","journal-title":"Chest"},{"key":"ref_23","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1186\/s12931-017-0693-8","article-title":"Prognostic value of mib-1 proliferation index in solitary fibrous tumors of the pleura implemented in a new score\u2014A multicenter study","volume":"18","author":"Diebold","year":"2017","journal-title":"Respir. Res."},{"key":"ref_24","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1038\/modpathol.2012.83","article-title":"Solitary fibrous tumor: A clinicopathological study of 110 cases and proposed risk assessment model","volume":"25","author":"Demicco","year":"2012","journal-title":"Mod. Pathol."},{"key":"ref_25","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1002\/jso.25634","article-title":"Predictors of behaviour in solitary fibrous tumours of the pleura surgically resected: Analysis of 107 patients","volume":"120","author":"Bellini","year":"2019","journal-title":"J. Surg. Oncol."},{"key":"ref_26","doi-asserted-by":"publisher","first-page":"1698","DOI":"10.1097\/JTO.0b013e3182653d64","article-title":"Malignant solitary fibrous tumors of the pleura: Retrospective review of a multicenter series","volume":"7","author":"Lococo","year":"2012","journal-title":"J. Thorac. Oncol."},{"key":"ref_27","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.athoracsur.2012.04.028","article-title":"Solitary fibrous tumor of the pleura: Outcomes of 157 complete resections in a single center","volume":"94","author":"Lahon","year":"2012","journal-title":"Ann. Thorac. Surg."},{"key":"ref_28","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1016\/S0003-4975(00)01908-1","article-title":"Localized (solitary) fibrous tumors of the pleura: An analysis of 55 patients","volume":"70","author":"Cardillo","year":"2000","journal-title":"Ann. Thorac. Surg."},{"key":"ref_29","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S1010-7940(00)00636-9","article-title":"Solitary fibrous tumour of the pleura: Surgical treatment","volume":"19","author":"Rena","year":"2001","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_30","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/S1010-7940(02)00099-4","article-title":"Solitary fibrous tumors of the pleura: Clinical characteristics, surgical treatment and outcome","volume":"21","author":"Magdeleinat","year":"2002","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Castaldo, V., Domenici, D., Biscosi, M.V., Ubiali, P., Miranda, C., Zanette, G., Mazzon, C., and Tonizzo, M. (Endocr. Metab. Immune Disord. Drug Targets, 2023). Doege-potter syndrome; a case of solitary fibrous pleura tumor associated with severe hypoglycemia: A case report in internal medicine, Endocr. Metab. Immune Disord. Drug Targets, online ahead of print.","DOI":"10.2174\/1871530323666230623112047"},{"key":"ref_32","first-page":"314","article-title":"A case of solitary fibrous pleura tumor associated with severe hypoglycemia: The doege-potter\u2019s syndrome","volume":"87","author":"Haddoub","year":"2016","journal-title":"Acta Biomed."},{"key":"ref_33","doi-asserted-by":"publisher","first-page":"120","DOI":"10.4046\/trd.2015.78.2.120","article-title":"A case of solitary fibrous pleura tumor associated with severe hypoglycemia: Doege-potter syndrome","volume":"78","author":"Jang","year":"2015","journal-title":"Tuberc. Respir. Dis."},{"key":"ref_34","doi-asserted-by":"publisher","first-page":"bcr2014207995","DOI":"10.1136\/bcr-2014-207995","article-title":"A common problem in the elderly with an uncommon cause: Hypoglycaemia secondary to the doege-potter syndrome","volume":"2015","author":"Tay","year":"2015","journal-title":"BMJ Case Rep."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Meng, W., Zhu, H.H., Li, H., Wang, G., Wei, D., and Feng, X. (2014). Solitary fibrous tumors of the pleura with doege-potter syndrome: A case report and three-decade review of the literature. BMC Res. Notes, 7.","DOI":"10.1186\/1756-0500-7-515"},{"key":"ref_36","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1097\/MCP.0b013e328352f696","article-title":"Solitary fibrous tumors of the pleura","volume":"18","author":"Cardillo","year":"2012","journal-title":"Curr. Opin. Pulm. Med."},{"key":"ref_37","doi-asserted-by":"publisher","first-page":"983","DOI":"10.2214\/ajr.158.5.1566702","article-title":"Ct findings in benign fibrous mesothelioma of the pleura: Pathologic correlation in nine patients","volume":"158","author":"Lee","year":"1992","journal-title":"AJR Am. J. Roentgenol."},{"key":"ref_38","first-page":"685","article-title":"Solitary fibrous tumour of the diaphragm","volume":"38","author":"Norton","year":"1997","journal-title":"J. Cardiovasc. Surg."},{"key":"ref_39","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/0720-048X(94)90278-X","article-title":"Localized pleural fibroma: Radiological features","volume":"18","author":"Versluis","year":"1994","journal-title":"Eur. J. Radiol."},{"key":"ref_40","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/00005382-199801000-00008","article-title":"Pictorial essay: Solitary fibrous tumor of the pleura","volume":"13","author":"Desser","year":"1998","journal-title":"J. Thorac. Imaging"},{"key":"ref_41","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.4081\/rt.2010.e1","article-title":"Imaging of benign solitary fibrous tumor of the pleura: A pictorial essay","volume":"2","author":"Cardinale","year":"2010","journal-title":"Rare Tumors"},{"key":"ref_42","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0009-9260(05)81459-X","article-title":"Primary malignant localized fibrous tumours of the pleura: Clinical, radiological and pathological features","volume":"45","author":"Saifuddin","year":"1992","journal-title":"Clin. Radiol."},{"key":"ref_43","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jtcvs.2009.01.026","article-title":"Solitary fibrous tumors of the pleura: Results of surgical treatment and long-term prognosis","volume":"138","author":"Nichols","year":"2009","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"ref_44","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1186\/s13019-023-02168-7","article-title":"Surgical considerations in the resection of solitary fibrous tumors of the pleura","volume":"18","author":"Ajouz","year":"2023","journal-title":"J. Cardiothorac. Surg."},{"key":"ref_45","doi-asserted-by":"publisher","first-page":"e534","DOI":"10.1097\/RLU.0000000000003598","article-title":"Solitary fibrous tumors of the pleura shown on 18f-fdg and 68ga-dota-fapi-04 pet\/ct","volume":"46","author":"Zhang","year":"2021","journal-title":"Clin. Nucl. Med."},{"key":"ref_46","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s12149-022-01723-x","article-title":"(18)f-fdg pet\/ct characteristics of solitary fibrous tumour of the pleura: Single institution experience","volume":"36","author":"Zhao","year":"2022","journal-title":"Ann. Nucl. Med."},{"key":"ref_47","doi-asserted-by":"publisher","first-page":"e1548","DOI":"10.1097\/MD.0000000000001548","article-title":"Solitary fibrous tumors of the pleura of the thorax: Ct and fdg pet characteristics in a tertiary referral center","volume":"94","author":"Yeom","year":"2015","journal-title":"Medicine"},{"key":"ref_48","doi-asserted-by":"publisher","first-page":"e336","DOI":"10.1097\/RLU.0000000000003570","article-title":"68ga-dotatoc pet\/ct in pleural solitary fibrous tumors","volume":"46","author":"Lococo","year":"2021","journal-title":"Clin. Nucl. Med."},{"key":"ref_49","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1186\/s13019-022-01881-z","article-title":"Resection of giant malignant solitary fibrous pleural tumor after interventional embolization: A case report and literature review","volume":"17","author":"Yao","year":"2022","journal-title":"J. Cardiothorac. Surg."},{"key":"ref_50","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/S0003-4975(01)03117-4","article-title":"Preoperative embolization of a massive solitary fibrous tumor of the pleura","volume":"73","author":"Weiss","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"ref_51","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1515\/med-2016-0042","article-title":"Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: Report of a case and review of the literature","volume":"11","author":"Perrotta","year":"2016","journal-title":"Open Med. (Wars)"},{"key":"ref_52","doi-asserted-by":"publisher","first-page":"2553","DOI":"10.1007\/s00268-010-0715-x","article-title":"Giant solitary fibrous tumor of the pleura: An analysis of five patients","volume":"34","author":"Guo","year":"2010","journal-title":"World J. Surg."},{"key":"ref_53","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/S0003-4975(03)00553-8","article-title":"Giant pleural fibroma with an abdominal vascular supply mimicking a pulmonary sequestration","volume":"76","author":"Kaul","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"ref_54","doi-asserted-by":"publisher","first-page":"e415","DOI":"10.1016\/j.athoracsur.2016.10.044","article-title":"Solitary fibrous tumor of the pleura with abdominal aortic blood supply","volume":"103","author":"Addagatla","year":"2017","journal-title":"Ann. Thorac. Surg."},{"key":"ref_55","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1093\/ejcts\/ezt481","article-title":"Computed tomography manifestations of a malignant solitary fibrous tumour of the pleura with distinct blood supply from celiac trunk","volume":"45","author":"Fan","year":"2014","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_56","doi-asserted-by":"publisher","first-page":"415","DOI":"10.5090\/kjtcs.2018.51.6.415","article-title":"Two-stage surgical treatment of a giant solitary fibrous tumor occupying the thoracic cavity","volume":"51","author":"Song","year":"2018","journal-title":"Korean J. Thorac. Cardiovasc. Surg."},{"key":"ref_57","doi-asserted-by":"publisher","first-page":"4090","DOI":"10.1245\/s10434-013-3242-9","article-title":"Prognosis of solitary fibrous tumors: A multicenter study","volume":"20","author":"Westerveld","year":"2013","journal-title":"Ann. Surg. Oncol."},{"key":"ref_58","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/S1010-7940(97)00274-1","article-title":"Contacting metastasis of a fibrous tumor of the pleura","volume":"12","author":"Nomori","year":"1997","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_59","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/j.athoracsur.2018.08.069","article-title":"A modern reaffirmation of surgery as the optimal treatment for solitary fibrous tumors of the pleura","volume":"107","author":"Yao","year":"2019","journal-title":"Ann. Thorac. Surg."},{"key":"ref_60","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1111\/1759-7714.12052","article-title":"Giant solitary fibrous tumor of the pleura requiring left pneumonectomy","volume":"5","author":"Petrella","year":"2014","journal-title":"Thorac. Cancer"},{"key":"ref_61","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1177\/0218492315614977","article-title":"Outcome of surgery in patients with solitary fibrous tumors of the pleura","volume":"24","author":"Bagheri","year":"2016","journal-title":"Asian Cardiovasc. Thorac. Ann."},{"key":"ref_62","doi-asserted-by":"publisher","first-page":"rjad008","DOI":"10.1093\/jscr\/rjad008","article-title":"Resection of a giant thoracic solitary fibrous tumor treated with preoperative arterial coiling followed by a double-level thoracotomy","volume":"2023","author":"Cox","year":"2023","journal-title":"J. Surg. Case Rep."},{"key":"ref_63","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1007\/s00432-020-03151-8","article-title":"Thoracic solitary fibrous tumors: An analysis of 70 patients who underwent surgical resection in a single institution","volume":"146","author":"Zhou","year":"2020","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"ref_64","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/S0003-4975(03)00663-5","article-title":"Localized fibrous tumors of the pleura: Clinical and surgical evaluation","volume":"76","author":"Altinok","year":"2003","journal-title":"Ann. Thorac. Surg."},{"key":"ref_65","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ijscr.2017.07.019","article-title":"Anterior mediastinal solitary fibrous tumor resection by da vinci((r)) surgical system in obese patient","volume":"38","author":"Amore","year":"2017","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_66","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1111\/ases.12987","article-title":"Cowboy technique for solitary fibrous tumor of the pleura via single-port video-assisted thoracoscopic surgery","volume":"15","author":"Nakanishi","year":"2022","journal-title":"Asian J. Endosc. Surg."},{"key":"ref_67","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1016\/j.athoracsur.2012.02.098","article-title":"Uniportal video-assisted thoracic resection of a solitary fibrous tumor of the pleura","volume":"94","author":"Rocco","year":"2012","journal-title":"Ann. Thorac. Surg."},{"key":"ref_68","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1016\/S1470-2045(16)00173-X","article-title":"Postoperative pain and quality of life after lobectomy via video-assisted thoracoscopic surgery or anterolateral thoracotomy for early stage lung cancer: A randomised controlled trial","volume":"17","author":"Bendixen","year":"2016","journal-title":"Lancet Oncol."},{"key":"ref_69","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s13019-020-01212-0","article-title":"Case report: Uniportal video-assisted thoracoscopic resection of a solitary fibrous tumor preoperatively predicted visceral pleura origin using dynamic chest radiography","volume":"15","author":"Tamura","year":"2020","journal-title":"J. Cardiothorac. 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Surg."},{"key":"ref_73","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1186\/1749-8090-6-122","article-title":"A silent gigantic solitary fibrous tumor of the pleura: Case report","volume":"6","author":"Furukawa","year":"2011","journal-title":"J. Cardiothorac. Surg."},{"key":"ref_74","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.lungcan.2008.10.006","article-title":"Radical resection of a giant, invasive and symptomatic malignant solitary fibrous tumour (sft) of the pleura","volume":"64","author":"Filosso","year":"2009","journal-title":"Lung Cancer"},{"key":"ref_75","doi-asserted-by":"publisher","first-page":"8","DOI":"10.21037\/acr.2017.11.02","article-title":"Extended thoracotomy with subcostal incision for giant solitary fibrous tumor of the diaphragm","volume":"1","author":"Yanagiya","year":"2017","journal-title":"AME Case Rep."},{"key":"ref_76","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.thorsurg.2021.04.009","article-title":"Implications of adverse biological factors and management of solitary fibrous tumors of the pleura","volume":"31","author":"Andrews","year":"2021","journal-title":"Thorac. Surg. Clin."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Ghanim, B., Baier, D., Pirker, C., M\u00fcllauer, L., Sinn, K., Lang, G., Hoetzenecker, K., and Berger, W. (2022). Trabectedin is active against two novel, patient-derived solitary fibrous pleural tumor cell lines and synergizes with ponatinib. Cancers, 14.","DOI":"10.3390\/cancers14225602"},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Levard, A., Derbel, O., M\u00e9eus, P., Ranch\u00e8re, D., Ray-Coquard, I., Blay, J.Y., and Cassier, P.A. (2013). Outcome of patients with advanced solitary fibrous tumors: The centre leon berard experience. BMC Cancer, 13.","DOI":"10.1186\/1471-2407-13-109"},{"key":"ref_79","doi-asserted-by":"publisher","first-page":"1385978","DOI":"10.1155\/2020\/1385978","article-title":"Clinical presentation, natural history, and therapeutic approach in patients with solitary fibrous tumor: A retrospective analysis","volume":"2020","author":"Timmermans","year":"2020","journal-title":"Sarcoma"},{"key":"ref_80","doi-asserted-by":"publisher","first-page":"245","DOI":"10.4103\/1817-1737.140142","article-title":"Recurrent intrathoracic solitary fibrous tumor: Remarkable response to radiotherapy","volume":"9","author":"Liu","year":"2014","journal-title":"Ann. Thorac. Med."},{"key":"ref_81","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S1010-7940(98)00213-9","article-title":"Localized fibrous tumours of the pleura: 15 new cases and review of the literature","volume":"14","author":"Suter","year":"1998","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"ref_82","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1016\/j.ijrobp.2018.04.024","article-title":"Radiation therapy as sole management for solitary fibrous tumors (sft): A retrospective study from the global sft initiative in collaboration with the sarcoma patients euronet","volume":"101","author":"Haas","year":"2018","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"ref_83","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s12032-009-9168-1","article-title":"Recurrent solitary fibrous tumor of the pleura: Significant response to radiotherapy","volume":"27","author":"Saynak","year":"2010","journal-title":"Med. Oncol."},{"key":"ref_84","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/2045-3329-3-7","article-title":"The role of chemotherapy in advanced solitary fibrous tumors: A retrospective analysis","volume":"3","author":"Park","year":"2013","journal-title":"Clin. Sarcoma Res."},{"key":"ref_85","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/S1470-2045(18)30676-4","article-title":"Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: A multicentre, single-arm, phase 2 trial","volume":"20","author":"Stacchiotti","year":"2019","journal-title":"Lancet Oncol."},{"key":"ref_86","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s13569-015-0022-2","article-title":"Pazopanib as first line treatment for solitary fibrous tumours: The royal marsden hospital experience","volume":"5","author":"Maruzzo","year":"2015","journal-title":"Clin. Sarcoma Res."},{"key":"ref_87","doi-asserted-by":"publisher","first-page":"4939","DOI":"10.1002\/cncr.26098","article-title":"Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor","volume":"117","author":"Park","year":"2011","journal-title":"Cancer"},{"key":"ref_88","doi-asserted-by":"publisher","first-page":"3171","DOI":"10.1093\/annonc\/mds143","article-title":"Sunitinib malate in solitary fibrous tumor (sft)","volume":"23","author":"Stacchiotti","year":"2012","journal-title":"Ann. Oncol."},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Franzen, D., Diebold, M., Soltermann, A., Schneiter, D., Kestenholz, P., Stahel, R., Weder, W., and Kohler, M. (2014). Determinants of outcome of solitary fibrous tumors of the pleura: An observational cohort study. BMC Pulm. Med., 14.","DOI":"10.1186\/1471-2466-14-138"},{"key":"ref_90","doi-asserted-by":"publisher","first-page":"100895","DOI":"10.1016\/j.rmcr.2019.100895","article-title":"Recurrence of a malignant solitary fibrous tumor of the pleura 17 years after primary tumor resection\u2014A case report","volume":"28","author":"Kovacs","year":"2019","journal-title":"Respir. Med. Case Rep."},{"key":"ref_91","doi-asserted-by":"publisher","first-page":"815","DOI":"10.6004\/jnccn.2022.0035","article-title":"Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology","volume":"207","author":"Kane","year":"2022","journal-title":"J. Natl. Compr. Cancer Netw."},{"key":"ref_92","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1093\/icvts\/ivab012","article-title":"Recurrence rates of surgically resected solitary fibrous tumours of the pleura: A systematic review and meta-analysis","volume":"32","author":"Liu","year":"2021","journal-title":"Interact. Cardiovasc. Thorac. Surg."},{"key":"ref_93","doi-asserted-by":"publisher","first-page":"472","DOI":"10.21037\/qims-20-598","article-title":"Intrapulmonary solitary fibrous tumor with adenofibromatous pattern with features of pleomorphic high grade sarcoma-a case report and an overview of the differential diagnosis","volume":"11","author":"Brunner","year":"2021","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_94","doi-asserted-by":"publisher","first-page":"12557","DOI":"10.1038\/s41598-017-12914-2","article-title":"Intrathoracic solitary fibrous tumor\u2014An international multicenter study on clinical outcome and novel circulating biomarkers","volume":"7","author":"Ghanim","year":"2017","journal-title":"Sci. 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