{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:35:51Z","timestamp":1779244551147,"version":"3.51.4"},"reference-count":31,"publisher":"MDPI AG","issue":"20","license":[{"start":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T00:00:00Z","timestamp":1697673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2022-00166271"],"award-info":[{"award-number":["RS-2022-00166271"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["KGCA2022IC2"],"award-info":[{"award-number":["KGCA2022IC2"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["KGCA2022IC3"],"award-info":[{"award-number":["KGCA2022IC3"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["KSERS-22-04"],"award-info":[{"award-number":["KSERS-22-04"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Catholic Medical Center Research Foundation","award":["RS-2022-00166271"],"award-info":[{"award-number":["RS-2022-00166271"]}]},{"name":"Catholic Medical Center Research Foundation","award":["KGCA2022IC2"],"award-info":[{"award-number":["KGCA2022IC2"]}]},{"name":"Catholic Medical Center Research Foundation","award":["KGCA2022IC3"],"award-info":[{"award-number":["KGCA2022IC3"]}]},{"name":"Catholic Medical Center Research Foundation","award":["KSERS-22-04"],"award-info":[{"award-number":["KSERS-22-04"]}]},{"name":"Research Supporting Program of the Korean Gastric Cancer Association","award":["RS-2022-00166271"],"award-info":[{"award-number":["RS-2022-00166271"]}]},{"name":"Research Supporting Program of the Korean Gastric Cancer Association","award":["KGCA2022IC2"],"award-info":[{"award-number":["KGCA2022IC2"]}]},{"name":"Research Supporting Program of the Korean Gastric Cancer Association","award":["KGCA2022IC3"],"award-info":[{"award-number":["KGCA2022IC3"]}]},{"name":"Research Supporting Program of the Korean Gastric Cancer Association","award":["KSERS-22-04"],"award-info":[{"award-number":["KSERS-22-04"]}]},{"name":"Korean Society of Endo-Laparoscopic and Robotic Surgery","award":["RS-2022-00166271"],"award-info":[{"award-number":["RS-2022-00166271"]}]},{"name":"Korean Society of Endo-Laparoscopic and Robotic Surgery","award":["KGCA2022IC2"],"award-info":[{"award-number":["KGCA2022IC2"]}]},{"name":"Korean Society of Endo-Laparoscopic and Robotic Surgery","award":["KGCA2022IC3"],"award-info":[{"award-number":["KGCA2022IC3"]}]},{"name":"Korean Society of Endo-Laparoscopic and Robotic Surgery","award":["KSERS-22-04"],"award-info":[{"award-number":["KSERS-22-04"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Appendicitis is a prevalent surgical emergency. Although appendectomy has traditionally been the go-to treatment, recent studies suggest antibiotics can be equally effective for uncomplicated cases. However, evidence is scant regarding patients with hematologic disorders. This study delves into the surgical risks tied to appendicitis in patients with underlying hematologic conditions. A retrospective analysis was carried out on patients diagnosed with appendicitis and hematologic disorders from January 2000 to June 2021. Patients were pinpointed using ICD-10 diagnostic codes, and surgical procedures were identified based on the hospital\u2019s surgical fee codes. Hematologic conditions were sorted into risk levels, and patient treatments were scrutinized. Among the 131 initially identified patients, 89 were included in the study. Out of these, 75 underwent surgical procedures, while 14 received non-surgical treatments. The surgical group displayed better preoperative laboratory outcomes. Clinical characteristics, hematologic disease risk, and severity of appendicitis appeared not to be related to surgical complications. Patients without surgical complications showed improvement in preoperative absolute neutrophil count (ANC) and platelet counts. Lower preoperative ANCs and platelet counts were associated with extended hospital stays. For patients with hematologic disorders diagnosed with appendicitis, thorough preoperative laboratory evaluations followed by minimally invasive appendectomy appear to be a safe route without heightening the risk of severe complications compared to non-surgical management.<\/jats:p>","DOI":"10.3390\/cancers15205049","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T05:43:28Z","timestamp":1697694208000},"page":"5049","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Risks Associated with Surgical Treatment for Appendicitis in Hematologic Patients"],"prefix":"10.3390","volume":"15","author":[{"given":"Seung Hyun","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8826-4136","authenticated-orcid":false,"given":"Sung-Soo","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3606-6074","authenticated-orcid":false,"given":"Ho Seok","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea"},{"name":"Division of Gastrointestinal Surgery, Department of Surgery, Seoul St. Mary\u2019s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,10,19]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.2188\/jea.JE20090011","article-title":"The epidemiology of appendicitis and appendectomy in South Korea: National registry data","volume":"20","author":"Lee","year":"2010","journal-title":"J. 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