{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:21:46Z","timestamp":1792513306923,"version":"4.5.0"},"reference-count":41,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T00:00:00Z","timestamp":1699401600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>This single-institution, retrospective study aimed to compare the surgical outcomes of single-port, multi-port, and robot-assisted laparoscopy, as well as laparotomy, in patients with endometrial cancer who underwent surgical staging between January 2006 and December 2017. This study evaluated various parameters, including disease-free survival (DFS), overall survival (OS), recurrence rate (RR), recurrence site, and intra- and postoperative complications. Propensity score matching was performed to account for baseline characteristics, and a total of 881 patients were included in the analysis. The 3-year DFS of single-port laparoscopy was similar to that of the other groups, but laparotomy exhibited a lower 3-year DFS compared to multi-port (p = 0.001) and robot-assisted (p = 0.031) laparoscopy. Single-port laparoscopy resulted in a significantly higher 3-year OS than laparotomy (p = 0.013). After propensity score matching, the four groups demonstrated similar survival outcomes (3-year DFS: p = 0.533; 3-year OS: p = 0.328) and recurrence rates (10.3%, 12.1%, 10.3%, and 15.9% in the single-port, multi-port, and robot-assisted laparoscopy and laparotomy groups, respectively, p = 0.552). Recurrence most commonly occurred in distant organs. The single-port laparoscopy group had the longest operative time (205.1 \u00b1 76.9 min) but the least blood loss (69.5 \u00b1 90.8 mL) and the shortest postoperative hospital stay (5.2 \u00b1 2.3 days). In contrast, the laparotomy group had the shortest operative time (163.4 \u00b1 51.0 min) but the highest blood loss (368.3 \u00b1 326.4 mL) and the longest postoperative hospital stay (10.3 \u00b1 4.6 days). The transfusion rate was 0% in the single-port laparoscopy group and 3.7% in the laparotomy group. Notably, the laparotomy group had the highest wound complication rate (p = 0.001), whereas no wound hernias were observed in the three minimally invasive approaches. In conclusion, the survival outcomes were comparable between the methods, with the benefit of lower blood loss and shorter hospital stay observed in the single-port laparoscopy group. This study suggests that single-port laparoscopy is a feasible approach for endometrial cancer surgical staging.<\/jats:p>","DOI":"10.3390\/cancers15225322","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T01:54:30Z","timestamp":1699408470000},"page":"5322","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of Single-Port Laparoscopy with Other Surgical Approaches in Endometrial Cancer Surgical Staging: Propensity-Score-Matched Analysis"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7849-1829","authenticated-orcid":false,"given":"Sang Hyun","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Graduate School, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"},{"name":"Department of Obstetrics and Gynecology, St. Vincent\u2019s Hospital, The Catholic University of Korea, Suwon 16247, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7948-1350","authenticated-orcid":false,"given":"Jung-Yun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women\u2019s Cancer Center, Yonsei Cancer Center, Institute of Women\u2019s Life Medical Science, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Ji","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women\u2019s Cancer Center, Yonsei Cancer Center, Institute of Women\u2019s Life Medical Science, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunghoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women\u2019s Cancer Center, Yonsei Cancer Center, Institute of Women\u2019s Life Medical Science, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7347-1052","authenticated-orcid":false,"given":"Young Tae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women\u2019s Cancer Center, Yonsei Cancer Center, Institute of Women\u2019s Life Medical Science, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8342-8701","authenticated-orcid":false,"given":"Sang Wun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Women\u2019s Cancer Center, Yonsei Cancer Center, Institute of Women\u2019s Life Medical Science, Yonsei University College of Medicine, Seoul 03722, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1002\/ijgo.13866","article-title":"Cancer of the corpus uteri: 2021 update","volume":"155","author":"Koskas","year":"2021","journal-title":"Int. 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