{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:24:37Z","timestamp":1792715077390,"version":"4.5.0"},"reference-count":45,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T00:00:00Z","timestamp":1699488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>We evaluate postoperative complications, aesthetic results and satisfaction outcomes in patients with breast cancer after intervening with a skin-sparing or nipple-sparing mastectomy with an immediate prosthetic reconstruction with or without a biological mesh. Patients with multifocal breast cancer, ductal carcinoma in situ with an indication for a mastectomy and cT2 tumors with no response to primary systemic treatment were included, whereas patients aged &gt;75 years, with inflammatory carcinoma, and severe circulatory disorders were excluded. Patients in the control group were reconstructed using a prosthesis, whereas the study group included patients reconstructed using a prosthesis and biological acellular porcine dermal mesh (Strattice\u2122). In both groups, the result was assessed using the BREAST-Q instrument. A total of 51 patients (62 intervened breasts) were included in the study group and 38 patients (41 intervened breasts) in the control group. Implant loss and removal occurred in three patients in the study group (5.9%) and nine patients in the control group (24.3%; p = 0.030). Infections appeared in three patients in the study group (4.8%) and three patients in the control group (7.3%; p = 1.00). Skin necrosis appeared in 5 patients in the study group (12.2%) and 11 patients in the control group (21.6%; p = 0.367). Seroma appeared in five patients in the study group (12.2%) and five patients in the control group (8.1%; p = 0.514). The BREAST-Q questionnaire is a comparison between both groups regarding \u201csatisfaction with breasts after surgery\u201d (p = 0.026), \u201csexual well-being after intervention\u201d (p = 0.010) and \u201csatisfaction with the information received\u201d (p = 0.049). We have noted a statistically significant decrease in implant loss in women receiving an implant with a biological mesh. A higher satisfaction was observed in patients reconstructed using Strattice\u2122, with statistically significant differences in three items.<\/jats:p>","DOI":"10.3390\/cancers15225349","type":"journal-article","created":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T10:19:27Z","timestamp":1699525167000},"page":"5349","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Single-Stage Immediate Breast Reconstruction with Acellular Dermal Matrix after Breast Cancer: Comparative Study and Evaluation of Breast Reconstruction Outcomes"],"prefix":"10.3390","volume":"15","author":[{"given":"Basilio","family":"Due\u00f1as-Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Unit of Breast Pathology, Department of Surgery, Hospital Complex of Ja\u00e9n, 23007 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Navarro-Cecilia","sequence":"additional","affiliation":[{"name":"Unit of Breast Pathology, Department of Surgery, Hospital Complex of Ja\u00e9n, 23007 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Luque-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Hospital Complex of Ja\u00e9n, 23007 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bel\u00e9n","family":"S\u00e1nchez-Andujar","sequence":"additional","affiliation":[{"name":"Unit of Breast Pathology, Department of Surgery, Hospital Complex of Ja\u00e9n, 23007 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Arsenio","family":"Garcel\u00e1n-Trigo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Complex of Ja\u00e9n, 23007 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9379-203X","authenticated-orcid":false,"given":"Mar\u00eda Jes\u00fas","family":"Ram\u00edrez-Exp\u00f3sito","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Ja\u00e9n, 23071 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2950-5614","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Mart\u00ednez-Martos","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Physiopathology Research Group CTS-1039, Department of Health Sciences, School of Experimental and Health Sciences, University of Ja\u00e9n, 23071 Ja\u00e9n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.breast.2021.02.004","article-title":"A multidisciplinary view of mastectomy and breast reconstruction: Understanding the challenges","volume":"56","author":"Offersen","year":"2021","journal-title":"Breast"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1089\/ten.tea.2008.0384","article-title":"A Porcine-Derived Acellular Dermal Scaffold That Supports Soft Tissue Regeneration: Removal of Terminal Galactose-alpha-(1,3)-Galactose and Retention of Matrix Structure","volume":"15","author":"Xu","year":"2009","journal-title":"Tissue Eng. 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