{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:47:23Z","timestamp":1784173643351,"version":"3.55.0"},"reference-count":68,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,6]],"date-time":"2024-01-06T00:00:00Z","timestamp":1704499200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: Risk of postoperative transient or permanent hypoparathyroidism represents one of the most common complications following total thyroidectomy. This risk increases if a cervical lymphadenectomy procedure must also be performed, as is usually the case in thyroid carcinoma patients. Parathyroid autofluorescence (AF) is a non-invasive method that aids intraoperative identification of parathyroid glands. Methods: In this prospective study, 189 patients with papillary thyroid cancer who underwent total thyroidectomy with central neck dissection were included. Patients were randomly allocated to one of two groups: NAF (no AF, surgery was performed without AF) and the AF group (surgery was performed with AF\u2014Fluobeam LX system, Fluoptics, Grenoble, France). Results: The number of excised lymph nodes was significantly higher in the AF compared to the NAF group, with mean values of 21.3 \u00b1 4.8 and 9.2 \u00b1 4.1, respectively. Furthermore, a significantly higher number of metastatic lymph nodes were observed in the AF group. Transient hypocalcemia recorded significantly lower rates in the AF group with 4.9% compared to 16.8% in the NAF group. Conclusions: AF use during total thyroidectomy with central neck dissection for papillary thyroid carcinoma patients, decreased the rate of iatrogenic parathyroid gland lesions, and increased the rate of lymphatic clearance.<\/jats:p>","DOI":"10.3390\/cancers16020258","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T05:21:38Z","timestamp":1704691298000},"page":"258","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Improvement in Central Neck Dissection Quality in Thyroid Cancer by Use of Tissue Autofluorescence"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7084-758X","authenticated-orcid":false,"given":"Octavian Constantin","family":"Neagoe","sequence":"first","affiliation":[{"name":"Second Clinic of General Surgery and Surgical Oncology, Emergency Clinical Municipal Hospital Timi\u0219oara, 300079 Timi\u0219oara, Romania"},{"name":"Second Discipline of Surgical Semiology, First Department of Surgery, \u201dVictor Babe\u0219\u201d University of Medicine, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7316-4749","authenticated-orcid":false,"given":"Mihaela","family":"Ionic\u0103","sequence":"additional","affiliation":[{"name":"Second Clinic of General Surgery and Surgical Oncology, Emergency Clinical Municipal Hospital Timi\u0219oara, 300079 Timi\u0219oara, Romania"},{"name":"Second Discipline of Surgical Semiology, First Department of Surgery, \u201dVictor Babe\u0219\u201d University of Medicine, 300041 Timi\u0219oara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.suc.2019.04.004","article-title":"Management of Nodal Disease in Thyroid Cancer","volume":"99","author":"Khokhar","year":"2019","journal-title":"Surg. 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