{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:06:38Z","timestamp":1787166398232,"version":"build-2736575974"},"reference-count":30,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T00:00:00Z","timestamp":1705276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of T\u00fcbingen","award":["3006-0-0"],"award-info":[{"award-number":["3006-0-0"]}]},{"name":"German Research Foundation (DFG)","award":["3006-0-0"],"award-info":[{"award-number":["3006-0-0"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Solid tumors of the cervicothoracic junction, the posterior mediastinum, or bilateral dorsal thoracic tumors represent a challenge in pediatric surgical oncology. The aim of this study was to evaluate trap-door thoracotomy and clamshell thoracotomy as surgical approaches. A single-center retrospective study of children with solid tumors in these specific localizations was performed. From 2015 to 2023, 26 children (17 girls; 9 boys) were treated at a median age of 54 months (range 8\u2013229). Tumor resection was performed for neuroblastoma (n = 11); metastatic disease (n = 7); malignant rhabdoid tumor (n = 4); Ewing sarcoma (n = 1); inflammatory myofibroblastic tumor (n = 1); rhabdomyosarcoma (n = 1); and neurofibroma (n = 1). The surgical goal of macroscopic complete excision was achieved in all of the 14 children who underwent trap-door thoracotomy and in 11 of the 12 children who underwent clamshell thoracotomy. There were no major complications. At a median follow-up of 8 months (range 0\u201360), the disease was under local control or in complete remission in 66.7% of the children. In conclusion, surgical resection of solid tumors of the cervicothoracic junction in children can be performed safely and successfully with trap-door thoracotomy and with clamshell thoracotomy for posterior mediastinal or bilateral dorsal thoracic tumors.<\/jats:p>","DOI":"10.3390\/cancers16020373","type":"journal-article","created":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T11:15:01Z","timestamp":1705317301000},"page":"373","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Trap-Door Thoracotomy and Clamshell Thoracotomy as Surgical Approaches for Neuroblastoma and Other Thoracic Tumors in Children"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1025-3496","authenticated-orcid":false,"given":"Benjamin F. B.","family":"Mayer","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery and Pediatric Urology, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias C.","family":"Schunn","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Pediatric Urology, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8909-0484","authenticated-orcid":false,"given":"Cristian","family":"Urla","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Pediatric Urology, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3279-8726","authenticated-orcid":false,"given":"J\u00fcrgen F.","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Division of Pediatric Radiology, Department of Diagnostic Radiology, University Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 1, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8667-8992","authenticated-orcid":false,"given":"Frank","family":"Fideler","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Intensive Care Medicine, University Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 1, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Neunhoeffer","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, Pulmonology and Intensive Care Medicine, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin U.","family":"Schuhmann","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Department of Neurosurgery, University Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 1, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5522-3250","authenticated-orcid":false,"given":"Steven W.","family":"Warmann","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Pediatric Urology, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery and Pediatric Urology, University Children\u2019s Hospital T\u00fcbingen, Hoppe-Seyler Stra\u00dfe 3, 72076 T\u00fcbingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1055\/s-2007-964873","article-title":"The Relevance of Surgical Therapy for Bilateral and\/or Multiple Pulmonary Metastases in Children","volume":"17","author":"Schweinitz","year":"2007","journal-title":"Eur. 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