{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T04:40:26Z","timestamp":1775018426940,"version":"3.50.1"},"reference-count":33,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008363","name":"Danish Cancer Society","doi-asserted-by":"publisher","award":["R306-A18169"],"award-info":[{"award-number":["R306-A18169"]}],"id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>(1) Background: Skin cancer is the most common cancer in transplant recipients. Timely and regular screening may reduce advanced disease. The study aimed to determine referral rates to screening, the incidence, and risk factors of skin cancer in a Danish liver transplant recipient cohort. (2) Methods: All first-time liver transplant recipients, &gt;18 years old, attending outpatient care between January 2018 and December 2021 were included. The referral rates and incidence of skin cancer\/preneoplastic lesions were calculated. Risk factors were assessed using Cox regression analyses. (3) Results: Of the 246 included recipients, 219 (89.0%) were referred to screening, and 102 skin cancer\/preneoplastic lesions were diagnosed in 32 (15.6%) recipients. The IR of any skin cancer\/preneoplastic lesion was 103.2 per 1000 person-years. BCC was the most frequent skin cancer followed by SCC, IR: 51.3 vs. 27.1 per 1000 person-years, respectively. No cases of MM were observed. The IR of actinic keratosis and Bowen\u2019s Disease were 48.1 vs. 13.2 per 1000 person-years, respectively. Time since transplantation was independently associated with skin cancer\/preneoplastic lesions, HR (95%CI) 2.81 (1.64\u20134.80). (4) Conclusions: The study determined the incidence and risk factors of skin cancer\/preneoplastic lesions in liver transplant recipients enrolled in a screening program, while demonstrating a high screening referral rate.<\/jats:p>","DOI":"10.3390\/cancers16061224","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T13:09:36Z","timestamp":1710940176000},"page":"1224","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Early Results of a Screening Program for Skin Cancer in Liver Transplant Recipients: A Cohort Study"],"prefix":"10.3390","volume":"16","author":[{"given":"Delal","family":"Akdag","sequence":"first","affiliation":[{"name":"Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Hepatic Malignancy Surgical Research Unit (HEPSURU), Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6391-7455","authenticated-orcid":false,"given":"Susanne Dam","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Hepatic Malignancy Surgical Research Unit (HEPSURU), Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Viro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3909-0643","authenticated-orcid":false,"given":"Dina Leth","family":"M\u00f8ller","sequence":"additional","affiliation":[{"name":"Viro-Immunology Research Unit, Department of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrine","family":"Togsverd-Bo","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5928-5042","authenticated-orcid":false,"given":"Emily","family":"Wenande","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1250-2035","authenticated-orcid":false,"given":"Merete","family":"Haedersdal","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"},{"name":"Department of Dermatology, Copenhagen University Hospital-Bispebjerg and Frederiksberg Hospital, 2400 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7068-1946","authenticated-orcid":false,"given":"Hans-Christian","family":"Pommergaard","sequence":"additional","affiliation":[{"name":"Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Hepatic Malignancy Surgical Research Unit (HEPSURU), Department of Surgery and Transplantation, Centre for Cancer and Organ Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1111\/ajt.14507","article-title":"Decreasing Incidence of Cancer after Liver Transplantation-A Nordic Population-Based Study over 3 Decades","volume":"18","author":"Nordin","year":"2018","journal-title":"Am. 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