{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:57:01Z","timestamp":1790787421446,"version":"4.1.0"},"reference-count":22,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background\/Objectives: Haematologic cancers, such acute leukaemia, lymphoma, and multiple myeloma, are associated with high morbidity and mortality rates, often exacerbated by malnutrition and functional decline. This study aims to evaluate the prognostic value of bioimpedance phase angle (PhA) and hand grip strength (HGS) as nutritional and clinical markers for predicting 12-month mortality in hospitalized patients with haematologic cancers. Methods: A retrospective observational study was conducted on 121 patients admitted to Hospital Quironsalud M\u00e1laga between January 2019 and June 2021. PhA was measured using bioelectrical impedance analysis (BIA) and HGS was assessed using a dynamometer. Nutritional status was evaluated through Subjective Global Assessment (SGA) and the Global Leadership Initiative on Malnutrition (GLIM) criteria. The primary outcome was 12-month mortality, analysed using ROC curves, Kaplan\u2013Meier survival estimates, and multivariate logistic regression models. Results: Lower PhA (&lt;3.8\u00b0 for females, &lt;5.4\u00b0 for males) and reduced HGS (&lt;17 kg for females, &lt;28 kg for males) were significantly associated with higher 12-month mortality (p &lt; 0.001). The optimal PhA cut-off showed high sensitivity (85.5%) and specificity (62.2%). Multivariate analysis confirmed PhA as an independent predictor of mortality (OR = 0.417, p = 0.023). Patients with lower PhA and HGS values exhibited reduced survival rates, emphasizing the importance of these markers in clinical practice. Conclusions: PhA and HGS are reliable, non-invasive tools for assessing prognosis in haematologic cancer patients. Incorporating these markers into routine care could improve risk stratification, guide nutritional interventions, and enhance patient outcomes.<\/jats:p>","DOI":"10.3390\/cancers17050886","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:54:38Z","timestamp":1741154078000},"page":"886","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Role of Bioimpedance Phase Angle and Hand Grip Strength in Predicting 12-Month Mortality in Patients Admitted with Haematologic Cancer"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1115-5715","authenticated-orcid":false,"given":"Lara","family":"Dalla Rovere","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"},{"name":"Department of Medicine and Dermatology, Faculty of Medicine, University of Malaga, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7469-5488","authenticated-orcid":false,"given":"Rocio","family":"Fern\u00e1ndez-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"},{"name":"Department of Medicine and Dermatology, Faculty of Medicine, University of Malaga, 29010 Malaga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain"},{"name":"Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3313-2312","authenticated-orcid":false,"given":"Alessandro","family":"Guerrini","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi ONLUS, 50143 Florence, Italy"},{"name":"Department of Science and Technology for Humans and the Environment, Universit\u00e0 Campus Bio-Medico di Roma, 00128 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5131-4478","authenticated-orcid":false,"given":"Mar\u00eda","family":"Garc\u00eda-Olivares","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"},{"name":"Department of Medicine and Dermatology, Faculty of Medicine, University of Malaga, 29010 Malaga, Spain"},{"name":"Department of Endocrinology and Nutrition, Regional de M\u00e1laga University Hospital, M\u00e1laga Biomedical Research Institute and BIONAND Platform (IBIMA), 29010 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Herola-Cobos","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Hardy-A\u00f1\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahinatu","family":"Awol-Tanko","sequence":"additional","affiliation":[{"name":"Department of Haematology, Quironsalud Malaga Hospital, 29004 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agust\u00edn","family":"Hernandez-Sanchez","sequence":"additional","affiliation":[{"name":"Department of Haematology, Quironsalud Malaga Hospital, 29004 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8570-184X","authenticated-orcid":false,"given":"Jos\u00e9 Manuel","family":"Garc\u00eda-Almeida","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition, Quironsalud Malaga Hospital, 29004 Malaga, Spain"},{"name":"Department of Medicine and Dermatology, Faculty of Medicine, University of Malaga, 29010 Malaga, Spain"},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, 29590 Malaga, Spain"},{"name":"Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, 29010 Malaga, Spain"},{"name":"Department of Endocrinology and Nutrition, Hospital Universitario Virgen de la Victoria, CIBEROBN, Carlos III Health Institute (ISCIII), University of M\u00e1laga, 29016 Malaga, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1182\/blood.2022015849","article-title":"Developing a Classification of Neoplasms in the Era of Precision 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