{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T01:16:39Z","timestamp":1779930999357,"version":"3.53.1"},"reference-count":111,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: The incidence of cancer in older patients is high, reaching 2.3 million world-wide in 2018 for patients aged over 80. Because the characteristics of this population make therapeutic choices difficult, co-management between geriatricians and other cancer specialists has gradually become essential. Methods: This narrative review aims to synthesize current data on the contribution of geriatric assessment in the management of elderly patients with non-colorectal digestive cancers. Oncogeriatric assessment is multi-domain, including the evaluation of co-morbidities, autonomy, nutrition, cognition, mood, and functional assessment. Results: Oncogeriatric parameters are predictive of mortality and adverse events. In the peri-operative phase of non-colorectal digestive cancer surgical management, geriatric management can assist in the decision-making process, identify frailties, and arrange a specific and personalized trimodal preoperative rehabilitation program, including nutritional management, adapted physical activity, and psychological care. Its aim is to limit the risks of confusion and of decompensation of comorbidities, mainly cardio-respiratory, which is associated with the highest morbidity in biliary-pancreatic surgery for older adults, facilitate recovery of previous autonomy when possible, and shorten hospital stay. For metastatic cancers, or during multimodal management, such as peri-operative chemotherapy for localized gastric cancers or pre-operative radio-chemotherapy for oesophageal or rectal cancers, specific assessment of the tolerance of chemotherapy is necessary. Neuropathic toxicity and chemobrain have a greater impact on elderly patients, with an increased loss of autonomy. Joint geriatric management can reduce the rate of grade 3\u20135 adverse effects of chemotherapy in particular and improve quality of life. Conclusions: Co-management between geriatricians and other specialties should be encouraged wherever possible.<\/jats:p>","DOI":"10.3390\/cancers17091589","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T08:20:53Z","timestamp":1746606053000},"page":"1589","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Geriatric Assessment and Management, Prehabilitation and Rehabilitation for Older Aldults with Non-Colorectal Digestive Cancers"],"prefix":"10.3390","volume":"17","author":[{"given":"Am\u00e9lie","family":"Aregui","sequence":"first","affiliation":[{"name":"Paris Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janina","family":"Estrada","sequence":"additional","affiliation":[{"name":"Geriatric Out-Patient Unit, Bretonneau Hospital, AP-HP, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeleine","family":"Lef\u00e8vre","sequence":"additional","affiliation":[{"name":"Paris Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0924-6646","authenticated-orcid":false,"given":"Anna","family":"Carteaux-Taieb","sequence":"additional","affiliation":[{"name":"Department of Digestive and Endocrine Surgery, Saint-Louis Hospital, AP-HP, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffroy","family":"Beraud-Chaulet","sequence":"additional","affiliation":[{"name":"Geriatrics Departement, Paul Brousse Hospital, AP-HP, 94800 Villejuif, France"},{"name":"Oncog\u00e9riatric Department, Gustave Roussy Institut, 94800 Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Hammel","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, Paul Brousse Hospital, AP-HP, Universit\u00e9 Paris Saclay, 94800 Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Fossey-Diaz","sequence":"additional","affiliation":[{"name":"Paris Nord Oncogeriatrics Coordination Unit, Bretonneau and Saint Louis Hospitals, AP-HP, 75018 Paris, France"},{"name":"Geriatrics Departement, Bretonneau Hospital, AP-HP, 75018 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8834-6927","authenticated-orcid":false,"given":"Thomas","family":"Aparicio","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Saint Louis Hospital, AP-HP, Universit\u00e9 Paris Cit\u00e9, 75010 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/ijc.33232","article-title":"Estimated global cancer incidence in the oldest adults in 2018 and projections to 2050","volume":"148","author":"Pilleron","year":"2021","journal-title":"Int. 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