{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T12:05:01Z","timestamp":1790597101661,"version":"4.1.0"},"reference-count":63,"publisher":"MDPI AG","issue":"13","license":[{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background\/Objectives: The aim of this case series is to evaluate the outcomes and safety of video-assisted mastectomy, illustrating the harmonious collaboration of oncologic and plastic surgery. This novel minimally invasive technique allows immediate prosthetic reconstruction and represents a cost-effective alternative to robotic breast surgery. Methods: Video-assisted, single-port nipple-sparing mastectomies were performed in patients with small to medium-sized breasts, followed by immediate direct-to-implant reconstruction with either prepectoral or dual plane implant placement. The patients\u2019 electronic medical records were analyzed, including demographic characteristics, operative times and histopathology reports. Results: A total of 18 patients underwent successful video-assisted mastectomy, without conversion to traditional open procedure. Fifteen of the operations were risk-reducing mastectomies. Twelve patients had complementary procedures performed concurrently on the previously operated contralateral breast (delayed reconstruction\/expander-to-implant exchange). Moreover, three patients benefited from additional minimally invasive techniques during the same surgery (prophylactic laparoscopic hysterectomy). Immediate breast reconstruction with polyurethane or microtextured breast implants up to 450 cc was performed, with satisfactory aesthetic outcomes and no cancer recurrences at 6 to 12 months postoperative follow-up. Early complications included transient hypercapnia, areolar congestion and cellulitis. No skin necrosis or implant-related complications were reported. The most frequently encountered late issues were contour irregularities. Conclusions: Video-assisted mastectomy facilitates the safe removal of proven pathologic or healthy breast tissue with minimal damage to the breast\u2019s skin envelope, facilitating single-stage breast reconstruction.<\/jats:p>","DOI":"10.3390\/cancers17132267","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T02:25:53Z","timestamp":1751941553000},"page":"2267","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Video-Assisted Mastectomy with Immediate Breast Reconstruction: First Clinical Experience and Outcomes in an Eastern European Medical Center"],"prefix":"10.3390","volume":"17","author":[{"given":"Adrian Daniel","family":"Tulin","sequence":"first","affiliation":[{"name":"Discipline of Anatomy, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of General Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela-Elena","family":"Ion","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaida","family":"Avino","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8603-5807","authenticated-orcid":false,"given":"Daniela-Elena","family":"Gheoca-Mutu","sequence":"additional","affiliation":[{"name":"Discipline of Anatomy, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdalah","family":"Abu-Baker","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Andrada-Elena","family":"\u021aig\u0103ran","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"software","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Teodora","family":"Timofan","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"visualization","vocabulary":"credit"}]},{"given":"Ileana","family":"Ostafi","sequence":"additional","affiliation":[{"name":"Discipline of Anatomy, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of General Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"software","vocabulary":"credit"}]},{"given":"Cristian Radu","family":"Jecan","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9376-6774","authenticated-orcid":false,"given":"Laura","family":"R\u0103ducu","sequence":"additional","affiliation":[{"name":"Discipline of Plastic Surgery, \u2018Carol Davila\u2019 University of Medicine and Pharmacy, 020021 Bucharest, Romania"},{"name":"Department of Plastic and Reconstructive Surgery, \u2018Prof. Dr Agrippa Ionescu\u2019 Clinical Emergency Hospital, 011356 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/00006534-198404000-00018","article-title":"The psychological impact of immediate breast reconstruction for women with early breast cancer","volume":"73","author":"Stevens","year":"1984","journal-title":"Plast. 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