{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T06:43:43Z","timestamp":1793515423461,"version":"4.5.0"},"reference-count":38,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: Lower limb lymphedema (LLL) is a frequent complication after gynecological cancer treatment, with a significant impact on quality of life. Despite the common use of compression therapy in managing established lymphedema, its role in prevention remains insufficiently explored. Methods: In this prospective randomized study, 64 women treated for gynecological malignancies were assigned to either a compression group (CG) using medium-pressure stockings (23\u201332 mmHg) or a no-compression group (NCG). All participants received standard education and physical activity guidance. Limb volume, symptom burden, and quality of life were assessed over 12 months. Results: The incidence of LLL was significantly lower in the CG (3.4%) compared to the NCG (38%, p = 0.003). Compression use resulted in significant reductions in limb volume and symptom severity, as well as improved physical functioning. Compliance with compression therapy was high, and patients reported good comfort and usability. Conclusions: Medium-pressure compression stockings combined with education and physical activity are effective and well-tolerated in preventing LLL following gynecological cancer treatment.<\/jats:p>","DOI":"10.3390\/cancers17152530","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T08:51:41Z","timestamp":1754038301000},"page":"2530","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of Compression Stockings in Prophylaxis of Lower Limb Lymphedema in Women Undergoing Treatment for Gynecological Malignancies: A Prospective Randomized Study"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8434-3745","authenticated-orcid":false,"given":"Joanna","family":"Kurpiewska-Pieni\u0105\u017cek","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, Andrzej Frycz Modrzewski Krakow University, 30-705 Krak\u00f3w, Poland"},{"name":"St. Lazarus Hospice, 31-831 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5980-0104","authenticated-orcid":false,"given":"Katarzyna","family":"Ocha\u0142ek","sequence":"additional","affiliation":[{"name":"St. Lazarus Hospice, 31-831 Krak\u00f3w, Poland"},{"name":"Department of Clinical Rehabilitation, University of Physical Culture, 31-571 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3705-3846","authenticated-orcid":false,"given":"Tomasz","family":"Gr\u0105dalski","sequence":"additional","affiliation":[{"name":"St. Lazarus Hospice, 31-831 Krak\u00f3w, Poland"},{"name":"Chair of Palliative Care, Medical Faculty, Andrzej Frycz Modrzewski Krakow University, 30-705 Krak\u00f3w, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej","family":"Szuba","sequence":"additional","affiliation":[{"name":"Department of Angiology and Internal Medicine, Wroclaw Medical University, 50-367 Wroc\u0142aw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.asjsur.2020.03.022","article-title":"Early prevention of complex decongestive therapy and rehabilitation exercise for prevention of lower extremity lymphedema after operation of gynecologic cancer","volume":"44","author":"Wu","year":"2021","journal-title":"Asian J. 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