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This review critically evaluates the various types of CVADs commonly employed in transplant settings, examining their indications, complications, and best practices to enhance patient outcomes. Moreover, it emphasizes the significance of broadening the selection algorithm for vascular devices and incorporating patient expectations and comfort into routine clinical practice.<\/jats:p>","DOI":"10.3390\/cancers17203325","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T07:29:38Z","timestamp":1760599778000},"page":"3325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Vascular Access Devices for Stem Cell Transplantation: A Review of Catheter Types\u2014A Crucial Step Towards the Enhancement of Patient Care"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4445-6192","authenticated-orcid":false,"given":"S\u0142awomir","family":"Milczarek","sequence":"first","affiliation":[{"name":"Department of Hematology and Transplantology, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8695-8863","authenticated-orcid":false,"given":"Piotr","family":"Kulig","sequence":"additional","affiliation":[{"name":"Department of General Pathology, Pomeranian Medical University, 70-111 Szczecin, Poland"},{"name":"Pharmaceutical Facility of Pomeranian Medical University, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliwia","family":"Piotrowska","sequence":"additional","affiliation":[{"name":"Department of Hematology and Transplantology, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Zuchma\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Hematology and Transplantology, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyna","family":"Brzosko","sequence":"additional","affiliation":[{"name":"Department of Hematology and Transplantology, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogus\u0142aw","family":"Machali\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Hematology and Transplantology, Pomeranian Medical University, 70-252 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1200\/JCO.2012.45.5733","article-title":"Central Venous Catheter Care for the Patient With Cancer: American Society of Clinical Oncology Clinical Practice Guideline","volume":"31","author":"Schiffer","year":"2013","journal-title":"J. Clin. Oncol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"v152","DOI":"10.1093\/annonc\/mdv296","article-title":"Central venous access in oncology: ESMO Clinical Practice Guidelines","volume":"26","author":"Sousa","year":"2015","journal-title":"Ann. Oncol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1177\/11297298241291248","article-title":"The NAVIGATE project: A GloVANet\u2013WoCoVA position statement on the nomenclature for vascular access devices","volume":"26","author":"Rens","year":"2025","journal-title":"J. Vasc. Access"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1177\/11297298241300792","article-title":"International experts consensus on optimal central vascular access device selection and management for patients with cancer","volume":"26","author":"Jahanzeb","year":"2024","journal-title":"J. Vasc. Access"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.clnesp.2020.11.019","article-title":"How to perform appropriate flushing after lipid emulsion administration using totally implantable venous access devices in long-term total parenteral nutrition and home parenteral nutrition","volume":"41","author":"Okamura","year":"2021","journal-title":"Clin. Nutr. ESPEN"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/NAN.0000000000000396","article-title":"Infusion Therapy Standards of Practice, 8th Edition","volume":"44","author":"Gorski","year":"2021","journal-title":"J. Infus. Nurs."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Cabrero, E.L., Robledo, R.T., Cu\u00f1ado, A.C., Sardelli, D.G., L\u00f3pez, C.H., Formatger, D.G., Perez, L.L., L\u00f3pez, C.E., and Moreno, A.T. (2023). Risk factors of catheter- associated bloodstream infection: Systematic review and meta-analysis. PLoS ONE, 18.","DOI":"10.1371\/journal.pone.0282290"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/hta25470","article-title":"Venous access devices for the delivery of long-term chemotherapy: The CAVA three-arm RCT","volume":"25","author":"Wu","year":"2021","journal-title":"Health Technol. Assess."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1007\/s00270-011-0271-2","article-title":"Venous Access Ports: Indications, Implantation Technique, Follow-Up, and Complications","volume":"35","author":"Walser","year":"2012","journal-title":"Cardiovasc. Interv. Radiol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1016\/S0924-8579(09)70565-5","article-title":"Peripheral venous catheters: An under-evaluated problem","volume":"34","author":"Zingg","year":"2009","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/tid.12175","article-title":"Incidence, risk factors, and outcome of bloodstream infections during the pre-engraftment phase in 521 allogeneic hematopoietic stem cell transplantations","volume":"16","author":"Blennow","year":"2014","journal-title":"Transpl. Infect. Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1086\/599376","article-title":"Clinical Practice Guidelines for the Diagnosis and Management of Intravascular Catheter-Related Infection: 2009 Update by the Infectious Diseases Society of America","volume":"49","author":"Mermel","year":"2009","journal-title":"Clin. Infect. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jhin.2021.10.008","article-title":"Catheter-associated bloodstream infection in patients with cancer: Comparison of left- and right-sided insertions","volume":"118","author":"Jones","year":"2021","journal-title":"J. Hosp. Infect."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3109\/08880018.2013.772683","article-title":"Catheter-associated Bloodstream Infections in Pediatric Hematology-Oncology Patients","volume":"30","author":"Celebi","year":"2013","journal-title":"Pediatr. Hematol. Oncol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13244-019-0770-2","article-title":"Complications of central venous port systems: A pictorial review","volume":"10","author":"Machat","year":"2019","journal-title":"Insights Imaging"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.ejso.2016.10.020","article-title":"Complication-related removal of totally implantable venous access port systems: Does the interval between placement and first use and the neutropenia-inducing potential of chemotherapy regimens influence their incidence? A four-year prospective study of 4045 patients","volume":"43","author":"Kakkos","year":"2017","journal-title":"Eur. J. Surg. Oncol. (EJSO)"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1002\/jhm.446","article-title":"Peripherally inserted central catheter use in the hospitalized patient: Is there a role for the hospitalist?","volume":"4","author":"Akers","year":"2009","journal-title":"J. Hosp. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"396","DOI":"10.5301\/jva.5000762","article-title":"Health-Related Quality of Life of Cancer Patients with Peripherally Inserted Central Catheter: A Pilot Study","volume":"18","author":"Kang","year":"2017","journal-title":"J. Vasc. Access"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jvsv.2022.03.007","article-title":"A systematic review and network meta-analysis of randomized controlled trials on choice of central venous access device for delivery of chemotherapy","volume":"10","author":"Yeow","year":"2022","journal-title":"J. Vasc. Surg. Venous Lymphat. Disord."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1177\/11297298211069256","article-title":"Difficult removal of totally implantable venous access devices in adult patients: Incidence, risk factors, and management","volume":"24","author":"Chatani","year":"2023","journal-title":"J. Vasc. Access"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/trf.14485","article-title":"Implantable vascular access devices \u2013 past, present, and future","volume":"58","author":"Lin","year":"2018","journal-title":"Transfusion"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1186\/cc8853","article-title":"Prevention of central venous catheter-related infection in the intensive care unit","volume":"14","author":"Frasca","year":"2010","journal-title":"Crit. Care"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1097\/MPH.0000000000000882","article-title":"Peripherally Inserted Central Catheters in Pediatric Oncology Patients: A 15-Year Population-based Review From Maritimes, Canada","volume":"40","author":"Borretta","year":"2018","journal-title":"J. Pediatr. Hematol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1007\/s12185-014-1677-9","article-title":"A role for peripherally inserted central venous catheters in the prevention of catheter-related blood stream infections in patients with hematological malignancies","volume":"100","author":"Sakai","year":"2014","journal-title":"Int. J. Hematol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s13613-018-0416-4","article-title":"Effectiveness of antimicrobial-coated central venous catheters for preventing catheter-related blood-stream infections with the implementation of bundles: A systematic review and network meta-analysis","volume":"8","author":"Wang","year":"2018","journal-title":"Ann. Intensiv. Care"},{"key":"ref_26","first-page":"1778","article-title":"Central Venous Catheter Colonization in Critically Ill Patients: A Prospective, Randomized, Controlled Study Comparing Standard with Two Antiseptic-Impregnated Catheters","volume":"101","author":"Mayr","year":"2005","journal-title":"Anesth. Analg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0934-8840(11)80203-3","article-title":"Prevention of Catheter-related Infections by Silver Coated Central Venous Catheters in Oncological Patients","volume":"283","author":"Goldschmidt","year":"1995","journal-title":"Zentralblatt Bakteriol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/1129729820916113","article-title":"Peripherally inserted central catheters inserted with current best practices have low deep vein thrombosis and central line\u2013associated bloodstream infection risk compared with centrally inserted central catheters: A contemporary meta-analysis","volume":"22","author":"Schears","year":"2020","journal-title":"J. Vasc. Access"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1007\/s00277-022-04908-6","article-title":"Peripherally inserted central venous catheters decrease central line-associated bloodstream infections and change microbiological epidemiology in adult hematology unit: A propensity score-adjusted analysis","volume":"101","author":"Nakaya","year":"2022","journal-title":"Ann. Hematol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ejca.2016.02.011","article-title":"Polyurethane versus silicone catheters for central venous port devices implanted at the forearm","volume":"59","author":"Wildgruber","year":"2016","journal-title":"Eur. J. Cancer"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"494","DOI":"10.3348\/kjr.2014.15.4.494","article-title":"Incidence and risk factors of infectious complications related to implantable venous-access ports","volume":"15","author":"Shim","year":"2014","journal-title":"Korean J. Radiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1017\/ice.2024.1","article-title":"A comparative analysis of infection and complication rates between single- and double-lumen ports","volume":"45","author":"Kozlowski","year":"2024","journal-title":"Infect. Control Hosp. Epidemiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1002\/ajh.26445","article-title":"The insertion site is the main risk factor for central venous catheter-related complications in patients with hematologic malignancies","volume":"97","author":"Heidenreich","year":"2022","journal-title":"Am. J. Hematol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2929","DOI":"10.1038\/s41409-021-01430-7","article-title":"Risk of infectious complications in adult patients after allogeneic hematopoietic stem cell transplantation depending on the site of central venous catheter insertion\u2014Multicenter prospective observational study, from the IDWP EBMT and Nurses Group of EBMT","volume":"56","author":"Snarski","year":"2021","journal-title":"Bone Marrow Transplant."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s15010-023-02029-4","article-title":"Impact of the insertion site of central venous catheters on central venous catheter-related bloodstream infections in patients with cancer: Results from a large prospective registry","volume":"51","author":"Hentrich","year":"2023","journal-title":"Infection"},{"key":"ref_36","unstructured":"Centers for Disease Control and Prevention (2025, July 25). Available online: https:\/\/www.cdc.gov\/infection-control\/media\/pdfs\/Strive-CLABSI103-508.pdf."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"329","DOI":"10.5301\/jva.5000239","article-title":"Peripherally Inserted Central Catheter (PICC)-Related Thrombosis in Critically Ill Patients","volume":"15","author":"Zochios","year":"2014","journal-title":"J. Vasc. Access"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1056\/NEJMra011883","article-title":"Preventing Complications of Central Venous Catheterization","volume":"348","author":"McGee","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"ref_39","first-page":"S127","article-title":"Challenging the Practice of Utilizing Central Venous Catheter Samples to Guide Tacrolimus Therapeutic Drug Monitoring Results","volume":"30","author":"Sapp","year":"2024","journal-title":"Biol. Blood Marrow Transplant."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Miller, L.M., Clark, E., Dipchand, C., Hiremath, S., Kappel, J., Kiaii, M., Lok, C., Luscombe, R., Moist, L., and Oliver, M. (2016). Hemodialysis Tunneled Catheter-Related Infections. Can. J. Kidney Health Dis., 3.","DOI":"10.1177\/2054358116669129"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1097\/00003246-199808000-00038","article-title":"Tunneling short-term central venous catheters to prevent catheter-related infection","volume":"26","author":"Randolph","year":"1998","journal-title":"Crit. Care Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1538-7836.2010.04126.x","article-title":"Risk factors for catheter-related thrombosis (CRT) in cancer patients: A patient-level data (IPD) meta-analysis of clinical trials and prospective studies","volume":"9","author":"Saber","year":"2011","journal-title":"J. Thromb. Haemost."},{"key":"ref_43","unstructured":"Flick, A.I., and Winters, R. (2024). Vascular Tunneled Central Catheter Access, StatPearls Publishing."},{"key":"ref_44","first-page":"1285","article-title":"Catheter-related thrombosis in stem cell recipients: Comparison of different types of catheter","volume":"109","author":"Milczarek","year":"2024","journal-title":"Haematologica"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0140-6736(09)60220-8","article-title":"Management of occlusion and thrombosis associated with long-term indwelling central venous catheters","volume":"374","author":"Baskin","year":"2009","journal-title":"Lancet"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/bjh.12474","article-title":"Catheter-related thrombosis in cancer patients","volume":"162","author":"Murray","year":"2013","journal-title":"Br. J. Haematol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1200\/JCO.2005.03.5600","article-title":"Incidence, Risk Factors, and Outcomes of Catheter-Related Thrombosis in Adult Patients With Cancer","volume":"24","author":"Lee","year":"2006","journal-title":"J. Clin. Oncol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e162","DOI":"10.1093\/cid\/cir257","article-title":"Guidelines for the Prevention of Intravascular Catheter-related Infections","volume":"52","author":"Alexander","year":"2011","journal-title":"Clin. Infect. Dis."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.4065\/81.9.1159","article-title":"The Risk of Bloodstream Infection in Adults With Different Intravascular Devices: A Systematic Review of 200 Published Prospective Studies","volume":"81","author":"Maki","year":"2006","journal-title":"Mayo Clin. Proc."},{"key":"ref_50","first-page":"531","article-title":"Peripherally inserted central catheters (PICCs) in the management of oncohematological patients submitted to autologous stem cell transplantation","volume":"21","author":"Bellesi","year":"2013","journal-title":"Support. Care Cancer"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Baier, C., Linke, L., Eder, M., Schwab, F., Chaberny, I.F., Vonberg, R.-P., and Ebadi, E. (2020). Incidence, risk factors and healthcare costs of central line-associated nosocomial bloodstream infections in hematologic and oncologic patients. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0227772"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1188\/13.CJON.297-302","article-title":"Reducing Central Line-Associated Bloodstream Infections in the Blood and Marrow Transplantation Population: A Review of the Literature","volume":"17","author":"Boubekri","year":"2013","journal-title":"Clin. J. Oncol. Nurs."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/00003246-200202000-00031","article-title":"Complications of central venous catheters: Internal jugular versus subclavian access\u2014A systematic review","volume":"30","author":"Ruesch","year":"2002","journal-title":"Crit. Care Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.clnu.2009.03.015","article-title":"Espen ESPEN Guidelines on Parenteral Nutrition: Central Venous Catheters (access, care, diagnosis and therapy of complications)","volume":"28","author":"Pittiruti","year":"2009","journal-title":"Clin. Nutr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2","DOI":"10.5758\/vsi.210062","article-title":"Efficacy and Safety of Midline Catheters with Integrated Wire Accelerated Seldinger Technique","volume":"38","author":"Jeon","year":"2022","journal-title":"Vasc. Spe\u0301c. Int."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.idc.2017.05.007","article-title":"Prevention of Central Line\u2013Associated Bloodstream Infections","volume":"31","author":"Bell","year":"2017","journal-title":"Infect. Dis. Clin. N. Am."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00277-020-04286-x","article-title":"Central venous catheter\u2013related infections in hematology and oncology: 2020 updated guidelines on diagnosis, management, and prevention by the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO)","volume":"100","author":"Schalk","year":"2021","journal-title":"Ann. Hematol."},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Milczarek, S., Kulig, P., Piotrowska, O., Zuchma\u0144ska, A., Wilk-Milczarek, E., and Machali\u0144ski, B. (2024). Incidence of Catheter-Associated Bloodstream Infections in Stem Cell Recipients\u2014Should We Be \u201cPICCy\u201d?. Cancers, 16.","DOI":"10.3390\/cancers16061239"},{"key":"ref_59","first-page":"3289","article-title":"Catheter-associated bloodstream infections and thrombotic risk in hematologic patients with peripherally inserted central catheters (PICC)","volume":"23","author":"Morano","year":"2015","journal-title":"Support. Care Cancer"},{"key":"ref_60","first-page":"4193","article-title":"Peripherally inserted central catheters in allogeneic hematopoietic stem cell transplant recipients","volume":"28","author":"Iori","year":"2020","journal-title":"Support. Care Cancer"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1111\/j.1445-5994.2011.02596.x","article-title":"Essential, but at what risk? A prospective study on central venous access in patients with haematological malignancies","volume":"42","author":"Dix","year":"2012","journal-title":"Intern. Med. J."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1182\/asheducation.V2012.1.638.3798656","article-title":"Catheter-related thrombosis: Lifeline or a pain in the neck?","volume":"2012","author":"Kamphuisen","year":"2012","journal-title":"Am. Soc. Hematol."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Lee, A.Y., and Levine, M.N. (2003). Venous Thromboembolism and Cancer: Risks and Outcomes. Circulation, 107.","DOI":"10.1161\/01.CIR.0000078466.72504.AC"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1086\/671737","article-title":"The Risk of Bloodstream Infection Associated with Peripherally Inserted Central Catheters Compared with Central Venous Catheters in Adults: A Systematic Review and Meta-Analysis","volume":"34","author":"Chopra","year":"2013","journal-title":"Infect. Control. Hosp. Epidemiol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"5611","DOI":"10.1182\/blood.V126.23.5611.5611","article-title":"Peripherally Inserted Central Catheters (PICCs) Implantation in the Clinical Management of Oncohematologic Patients: Results of a Large Multicenter, Retrospective Study of the REL Group (Rete Ematologica Lombarda - Lombardy Hematologic Network, Italy)","volume":"126","author":"Fracchiolla","year":"2015","journal-title":"Blood"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.bja.2022.08.036","article-title":"Mechanical complications after central venous catheterisation in the ultrasound-guided era: A prospective multicentre cohort study","volume":"129","author":"Adrian","year":"2022","journal-title":"Br. J. Anaesth."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"e17894","DOI":"10.1097\/MD.0000000000017894","article-title":"The anticoagulants rivaroxaban and low molecular weight heparin prevent PICC-related upper extremity venous thrombosis in cancer patients","volume":"98","author":"Lv","year":"2019","journal-title":"Medicine"},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1038\/s41409-023-02039-8","article-title":"Evaluation of venous thromboembolism prophylaxis protocol in hematopoietic cell transplant patients","volume":"58","author":"Lee","year":"2023","journal-title":"Bone Marrow Transplant."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1111\/jocn.16020","article-title":"Dual-lumen power injectable peripherally inserted central catheters in allogeneic hematopoietic stem cell transplantation: A prospective observational study","volume":"31","author":"Shih","year":"2022","journal-title":"J. Clin. Nurs."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.2147\/PPA.S142556","article-title":"Comparison of three types of central venous catheters in patients with malignant tumor receiving chemotherapy","volume":"ume 11","author":"Fang","year":"2017","journal-title":"Patient Prefer. Adherence"},{"key":"ref_71","doi-asserted-by":"crossref","unstructured":"Chen, Y.B., Bao, H.S., Hu, T.T., He, Z., Wen, B., Liu, F.T., Su, F.X., Deng, H.R., and Wu, J.N. (2022). Comparison of comfort and complications of Implantable Venous Access Port (IVAP) with ultrasound guided Internal Jugular Vein (IJV) and Axillary Vein\/Subclavian Vein (AxV\/SCV) puncture in breast cancer patients: A randomized controlled study. BMC Cancer, 22.","DOI":"10.1186\/s12885-022-09228-6"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/ajcp\/aqx145","article-title":"Assessment of the Measurement Error in Cyclosporine Levels Drawn Between Peripheral and Central Sources","volume":"149","author":"Shih","year":"2017","journal-title":"Am. J. Clin. Pathol."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"232","DOI":"10.4103\/0971-5851.195732","article-title":"Outcomes, cost comparison, and patient satisfaction during long-term central venous access in cancer patients: Experience from a Tertiary Care Cancer Institute in South India","volume":"37","author":"Babu","year":"2016","journal-title":"Indian J. Med Paediatr. Oncol."}],"container-title":["Cancers"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-6694\/17\/20\/3325\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T07:42:08Z","timestamp":1760600528000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-6694\/17\/20\/3325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,15]]},"references-count":73,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2025,10]]}},"alternative-id":["cancers17203325"],"URL":"https:\/\/doi.org\/10.3390\/cancers17203325","relation":{},"ISSN":["2072-6694"],"issn-type":[{"value":"2072-6694","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,15]]}}}