{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T22:15:23Z","timestamp":1769120123148,"version":"3.49.0"},"reference-count":57,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Dutch Research Council","doi-asserted-by":"crossref","award":["023.022.04"],"award-info":[{"award-number":["023.022.04"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background\/Objectives: Adolescents and young adults (AYAs) with cancer often begin their careers later in life and are at risk of negative work-related outcomes. Research into and tailored support programs for AYAs diagnosed during higher education remain limited. An improved understanding of AYAs\u2019 experiences is essential in guiding the development of age-appropriate support programs. This study explored the impact of cancer and the challenges AYAs face in educational participation and the transition to work. Methods: A qualitative study was conducted with thirteen AYAs diagnosed with cancer during higher education. Participants were interviewed using a semi-structured guide. In collaboration with patient experts as co-researchers, data were analyzed via thematic analysis. Results: Eight analytically derived themes reflected AYA students\u2019 experiences: (1) Meaning and importance of education, (2) Reduced performance, (3) Recovery and expectations, (4) Interruption and delay, (5) Transition to work, (6) Disclosure, (7) Challenges related to the context of students, and (8) Experienced lack of support. The themes were clustered into four overarching thematic categories: Meaningful participation, Impact on performance, Academic progress and career transition, and Challenges in navigation. Conclusions: Our findings provide greater insight into the significance of educational participation for AYAs. AYA students encounter challenges stemming from both diagnosis-related changes in functioning and from contextual factors tied to their roles as students and new starters in the labor market. Navigating the healthcare, education, and social systems is complex and AYAs often lack adequate support when resuming their education or transitioning to work. Tailored support programs in healthcare and educational settings should be developed to help AYAs harness their strong motivation to resume studies, enter the labor market, and achieve their full potential.<\/jats:p>","DOI":"10.3390\/cancers18020325","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T11:27:58Z","timestamp":1768908478000},"page":"325","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Understanding the Experiences of Adolescents and Young Adults Diagnosed with Cancer During Higher Education\u2014An Exploratory Interview Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5522-1701","authenticated-orcid":false,"given":"Anke W.","family":"Boumans","sequence":"first","affiliation":[{"name":"Department of Occupational Therapy and Centre of Expertise Urban Vitality, Amsterdam University of Applied Sciences, 1105 BD Amsterdam, The Netherlands"},{"name":"Centre of Expertise Urban Vitality, Amsterdam University of Applied Sciences, 1105 BD Amsterdam, The Netherlands"},{"name":"Department of Public and Occupational Health, Amsterdam UMC Location AMC, University of Amsterdam, 1100 DD Amsterdam, The Netherlands"},{"name":"Department of Medical Oncology, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8288-0002","authenticated-orcid":false,"given":"Margo J.","family":"van Hartingsveldt","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy and Centre of Expertise Urban Vitality, Amsterdam University of Applied Sciences, 1105 BD Amsterdam, The Netherlands"},{"name":"Centre of Expertise Urban Vitality, Amsterdam University of Applied Sciences, 1105 BD Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1942-6848","authenticated-orcid":false,"given":"Angela G. E. M.","family":"de Boer","sequence":"additional","affiliation":[{"name":"Department of Public and Occupational Health, Amsterdam UMC Location AMC, University of Amsterdam, 1100 DD Amsterdam, The Netherlands"},{"name":"Societal Participation and Health, Amsterdam Public Health Research Institute, 1105 AZ Amsterdam, The Netherlands"},{"name":"Cancer Center Amsterdam, Cancer Treatment and Quality of Life, 1006 BE Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maaike M.","family":"Brus","sequence":"additional","affiliation":[{"name":"Independent Researcher, 7522 NB Enschede, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floor M.","family":"Hoddenbagh-Bosdijk","sequence":"additional","affiliation":[{"name":"Independent Researcher, 1411 HB Naarden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milou J. P.","family":"Reuvers","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"},{"name":"Department of Public Health, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack D.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"},{"name":"Department of Public Health, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-7767","authenticated-orcid":false,"given":"Martijn M.","family":"Stuiver","sequence":"additional","affiliation":[{"name":"Centre of Expertise Urban Vitality, Amsterdam University of Applied Sciences, 1105 BD Amsterdam, The Netherlands"},{"name":"Centre for Quality of Life, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"},{"name":"Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1387-8686","authenticated-orcid":false,"given":"Olga","family":"Husson","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Netherlands Cancer Institute\u2014Antoni van Leeuwenhoek, 1066 CX Amsterdam, The Netherlands"},{"name":"Department of Public Health, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands"},{"name":"Department Surgical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e27486","DOI":"10.1002\/pbc.27486","article-title":"Understanding care and outcomes in adolescents and young adults with cancer: A review of the AYA HOPE study","volume":"66","author":"Smith","year":"2018","journal-title":"Pediatr. 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