{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T14:11:38Z","timestamp":1785507098646,"version":"3.56.0"},"reference-count":88,"publisher":"MDPI AG","issue":"15","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background\/Objectives: Nutritional impairment is common across the cancer care continuum and may negatively affect treatment tolerance, functional status, quality of life, and caregiver burden. Digital tools may offer new opportunities to extend nutritional care beyond conventional clinical encounters, but their application in oncology remains heterogeneous and poorly defined. This narrative review aims to describe the current landscape of digital nutritional care in oncology, focusing on quality of life and patient perspectives while also considering the emerging role of caregivers. Methods: We conducted a narrative review of the available evidence on digital nutritional and lifestyle interventions in cancer care, including mobile applications, web-based platforms, teleconsultations, SMS- or email-based communication, remote monitoring systems, and hybrid models. Results: Digital nutritional and lifestyle interventions have been evaluated across active treatment, postoperative recovery, and survivorship. Available studies indicate that these interventions are generally feasible and may improve nutritional status, dietary behaviors, and physical activity levels. However, quality-of-life outcomes remain heterogeneous and have not been consistently assessed across studies. Some interventions combining digital tools with personalization, professional feedback, behavioral support, or clinically actionable monitoring reported favorable patient-centered outcomes. However, heterogeneity across studies limits the interpretation of these findings and the identification of specific intervention features associated with effectiveness. Patient and caregiver perspectives further highlight the importance of usability, trust, access to reliable information, communication with healthcare professionals, and practical support in the home setting. Conclusions: Digital nutritional care has the potential to extend and strengthen the delivery of nutritional care. Rather than replacing conventional interventions, it should be implemented through hybrid, supervised, equitable, and clinically integrated models. Future studies should consistently assess quality of life and other patient-reported outcomes while also addressing caregiver needs, digital burden, psychological safety, and inequalities in access.<\/jats:p>","DOI":"10.3390\/cancers18152468","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T13:23:20Z","timestamp":1785504200000},"page":"2468","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Digital Nutritional Care in Oncology: Opportunities to Enhance Quality of Life and Support Patient-Centered Care"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1092-3493","authenticated-orcid":false,"given":"Elisa","family":"Mattavelli","sequence":"first","affiliation":[{"name":"Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy"},{"name":"Clinical Nutrition and Dietetics Unit, Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8783-1904","authenticated-orcid":false,"given":"Valentina","family":"Da Prat","sequence":"additional","affiliation":[{"name":"Clinical Nutrition and Dietetics Unit, Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Perrone","sequence":"additional","affiliation":[{"name":"Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"De Simeis","sequence":"additional","affiliation":[{"name":"Clinical Nutrition and Dietetics Unit, Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0607-2154","authenticated-orcid":false,"given":"Laura","family":"Boldrini","sequence":"additional","affiliation":[{"name":"Multidisciplinary Clinical Nutrition Service, European Institute of Oncology, IRCCS, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6672-0233","authenticated-orcid":false,"given":"Salvatore","family":"Corallo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy"},{"name":"Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annarita","family":"Sabbatini","sequence":"additional","affiliation":[{"name":"Multidisciplinary Clinical Nutrition Service, European Institute of Oncology, IRCCS, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9419-7160","authenticated-orcid":false,"given":"Paolo","family":"Pedrazzoli","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, Italy"},{"name":"Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8548-323X","authenticated-orcid":false,"given":"Roberto","family":"Biffi","sequence":"additional","affiliation":[{"name":"Division of Gynecology-Peritoneal Cancer Surgery Unit, Multidisciplinary Clinical Nutrition Service, European Institute of Oncology, IRCCS, 20141 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9379-3569","authenticated-orcid":false,"given":"Riccardo","family":"Caccialanza","sequence":"additional","affiliation":[{"name":"Clinical Nutrition and Dietetics Unit, Department of Oncology, Comprehensive Cancer Center, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy"},{"name":"Department of Oncology and Hematology-Oncology, University of Milan, 20123 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1016\/j.clnu.2021.02.005","article-title":"ESPEN Practical Guideline: Clinical Nutrition in Cancer","volume":"40","author":"Muscaritoli","year":"2021","journal-title":"Clin. 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