{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T02:52:14Z","timestamp":1789872734846,"version":"4.0.1"},"reference-count":189,"publisher":"MDPI AG","issue":"16","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cDun\u0103rea de Jos\u201d University of Galati","award":["RO50411550"],"award-info":[{"award-number":["RO50411550"]}]},{"award":["RO50411550"],"award-info":[{"award-number":["RO50411550"]}],"id":[{"id":"https:\/\/ror.org\/052sta926","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Artificial intelligence (AI) is increasingly being integrated into medical practice, offering promising tools to improve diagnostic accuracy and clinical efficiency. In the field of breast pathology, AI applications, particularly those based on deep learning (DL) and machine learning (ML), are emerging as decision-support tools in both diagnostic and prognostic workflows. This review provides a comprehensive overview of current AI-based approaches, with a focus on their clinical utility in tumor detection, histological classification, biomarker assessment, and prediction of treatment response. In addition to summarizing available AI platforms, the review critically examines their level of clinical validation, regulatory status, and integration into routine practice. Key challenges are also discussed. Overall, AI is expected to play an increasingly important role in supporting pathologists and advancing precision medicine in breast cancer management.<\/jats:p>","DOI":"10.3390\/cancers18162723","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T15:51:05Z","timestamp":1787327465000},"page":"2723","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Artificial Intelligence for Diagnostic and Prognostic Support in Breast Cancer: A Literature Overview"],"prefix":"10.3390","volume":"18","author":[{"given":"Diana Gina","family":"Poalelungi","sequence":"first","affiliation":[{"name":"Medical and Pharmaceutical Research Center, Faculty of Medicine and Pharmacy, \u201cDun\u0103rea de Jos\u201d University of Galati, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6473-3890","authenticated-orcid":false,"given":"Anca Iulia","family":"Neagu","sequence":"additional","affiliation":[{"name":"Saint John Clinical Emergency Hospital for Children, 800487 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Fulga","sequence":"additional","affiliation":[{"name":"Medical and Pharmaceutical Research Center, Faculty of Medicine and Pharmacy, \u201cDun\u0103rea de Jos\u201d University of Galati, 800008 Galati, Romania"},{"name":"Saint Apostle Andrew Emergency County Clinical Hospital, 177 Brailei St., 800578 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5853-393X","authenticated-orcid":false,"given":"Octavian Stefan","family":"Patrascanu","sequence":"additional","affiliation":[{"name":"Medical and Pharmaceutical Research Center, Faculty of Medicine and Pharmacy, \u201cDun\u0103rea de Jos\u201d University of Galati, 800008 Galati, Romania"},{"name":"University Emergency Hospital of Bucharest, 169 Splaiul Independentei St., 050098 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7414-9348","authenticated-orcid":false,"given":"Iuliu","family":"Fulga","sequence":"additional","affiliation":[{"name":"Medical and Pharmaceutical Research Center, Faculty of Medicine and Pharmacy, \u201cDun\u0103rea de Jos\u201d University of Galati, 800008 Galati, Romania"},{"name":"Saint Apostle Andrew Emergency County Clinical Hospital, 177 Brailei St., 800578 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"ref_1","first-page":"7","article-title":"Cancer Statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA Cancer J. 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