{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:51:39Z","timestamp":1791193899683,"version":"4.1.0"},"reference-count":43,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:00:00Z","timestamp":1790985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"A. Stuart Hamilton III and Betty S. Hamilton"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Purpose: Assess the feasibility of a 6-month individualized nutrition counseling and exercise program targeting a 10% body weight loss in breast cancer (BC) survivors, with secondary endpoints assessing metabolic parameters, cardiovascular function, and quality of life. Methods: This single-arm pilot study enrolled BC survivors with body mass index (BMI) \u2265 25 kg\/m2 in a counseling program with a registered dietitian, consisting of in-person and telephone visits over six months. Outcomes measured included weight, body composition, blood markers, cardiovascular function, and quality of life at 3 and 6 months. Results: A total of 78 breast cancer survivors were enrolled; 59 remained in the study at Month 3, and 54 completed the 6-month follow-up. The median age of participants was 58.5 years, and the cohort was predominantly White (72.4%). Among the 54 participants who completed 6-month follow-up, 11.1% achieved &gt;10% weight loss and 29.6% achieved &gt;5% weight loss. At 3 months, significant reductions were observed in BMI, body fat composition, and hemoglobin A1c (HbA1c), along with improvements in quality of life, depression, and anxiety. At 6 months, significant reductions were observed in weight, BMI, and body fat composition, with improvements in quality of life and depressive symptoms. Conclusions: This hybrid nutrition and exercise program was associated with observed improvements in weight loss and improved quality of life among BC survivors. Implications for Cancer Survivors: A low-burden, hybrid nutrition and exercise program integrated into routine oncology follow-up may help breast cancer survivors achieve weight loss while improving their quality of life.<\/jats:p>","DOI":"10.3390\/cancers18193198","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:57:18Z","timestamp":1791190638000},"page":"3198","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quality-of-Life and Weight Loss Outcomes Following an Individualized Nutrition and Physical Activity Counseling Program in Breast Cancer Survivors: A Prospective Single-Arm Pilot Study"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3186-3887","authenticated-orcid":false,"given":"Shashi","family":"Kant","sequence":"first","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Ahmad","family":"Alhalabi","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7335-9319","authenticated-orcid":false,"given":"Nadeem","family":"Bilani","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8991-7445","authenticated-orcid":false,"given":"Iktej Singh","family":"Jabbal","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Mar\u00eda","family":"Herr\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, 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Center, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3533-111X","authenticated-orcid":false,"given":"Kaylee","family":"Sarna","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Cleveland Clinic Florida, Weston, FL 33331, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]},{"given":"Amanda","family":"Stevenson","sequence":"additional","affiliation":[{"name":"Department of Hematology-Oncology, Maroone Cancer Center, Cleveland Clinic Florida, Weston, FL 33331, 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