{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:23:47Z","timestamp":1760243027686,"version":"build-2065373602"},"reference-count":30,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T00:00:00Z","timestamp":1429660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancers"],"abstract":"<jats:p>Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) is associated with multiple metabolic complications, previously predominantly evaluated in the white population. Methods: A chart-based retrospective review was conducted on black patients with PCa, considered for ADT, from September 2007 to July 2010. Baseline data were collected on body mass index (BMI), vitamin-D status, bone mineral density (BMD), dyslipidemia and diabetes. Overweight and obesity were classified as BMI \u2265 25 and BMI \u2265 30, respectively. Vitamin-D sufficiency was defined as levels \u226530 ng\/mL, insufficiency as &lt;30 ng\/mL and deficiency as \u226420 ng\/mL. Osteopenia was defined as T scores between \u22121 to \u22122.5 and osteoporosis when T scores \u2264\u22122.5. Results: Of the initial cohort of 130 black men, 111 (85.4%) patients underwent ADT. At baseline, average BMI was 28.1 \u00b1 5.9 with 43.3% of men being overweight and 30.8% obese. More than one-third of the patients had  pre-existing dyslipidemia while 28.8% were diabetics. 50% were vitamin-D deficient while 41% had low bone mass. Conclusions: Black men with PCa presenting for consideration of ADT have a high prevalence of existing metabolic risk factors. Close monitoring of this patient population is needed during ADT to prevent and treat metabolic complications.<\/jats:p>","DOI":"10.3390\/cancers7020679","type":"journal-article","created":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T12:14:23Z","timestamp":1429704863000},"page":"679-687","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cardiometabolic and Skeletal Risk Factors in Black Men with Prostate Cancer Starting Androgen Deprivation Therapy"],"prefix":"10.3390","volume":"7","author":[{"given":"Orvar","family":"Gunnarsson","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Hematology and Oncology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 16 Penn Tower, Philadelphia, PA 19104, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shehzad","family":"Basaria","sequence":"additional","affiliation":[{"name":"Department of Medicine, Section of Men's Health, Aging and Metabolism, Brigham and Women's Hospital, Boston, MA 02115, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gretchen","family":"Gignac","sequence":"additional","affiliation":[{"name":"Department of Medicine, Section of Hematology and Oncology, Boston University School of Medicine, Boston, MA 02118, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2015,4,22]]},"reference":[{"key":"ref_1","unstructured":"American Cancer Society (ACS) (2013). 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