{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T03:35:36Z","timestamp":1762054536956,"version":"build-2065373602"},"reference-count":17,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Human Genome Research Institute (NHGRI)","award":["U24HG003345","208349\/Z\/17\/Z"],"award-info":[{"award-number":["U24HG003345","208349\/Z\/17\/Z"]}]},{"name":"Wellcome Trust","award":["U24HG003345","208349\/Z\/17\/Z"],"award-info":[{"award-number":["U24HG003345","208349\/Z\/17\/Z"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cells"],"abstract":"<jats:p>This commentary is written in response to the recent article from Herring et al., discussing the eradication of the offensive term \u201cretardation\u201d from gene nomenclature. We discuss the work of the HUGO (Human Genome Organisation) Gene Nomenclature Committee (HGNC) and outline the steps already taken to remove this term from our gene names. We also highlight the latest nomenclature changes made as a result of discussions with the authors and agreement with the European Fragile X Network.<\/jats:p>","DOI":"10.3390\/cells11121937","type":"journal-article","created":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T01:48:12Z","timestamp":1655430492000},"page":"1937","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comment on Herring et al. The Use of \u201cRetardation\u201d in FRAXA, FMRP, FMR1 and Other Designations. Cells 2022, 11, 1044"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8380-5247","authenticated-orcid":false,"given":"Elspeth","family":"Bruford","sequence":"first","affiliation":[{"name":"Department of Haematology, University of Cambridge School of Clinical Medicine, Cambridge CB2 0PT, UK"},{"name":"HUGO Gene Nomenclature Committee, EMBL-EBI, European Molecular Biology Laboratory, Wellcome Genome Campus, Hinxton CB10 1SD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the HUGO Gene Nomenclature Committee (HGNC)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Herring, J., Johnson, K., and Richstein, J. (2022). The Use of \u201cRetardation\u201d in FRAXA, FMRP, FMR1 and Other Designations. Cells, 11.","DOI":"10.3390\/cells11061044"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1136\/jnnp.6.3-4.154","article-title":"A pedigree of mental defect showing sex-linkage","volume":"6","author":"Martin","year":"1943","journal-title":"J. Neurol. Psychiatry"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/ajmg.1320230157","article-title":"DNA Studies of X-Linked Mental Retardation Associated with a Fragile Site at Xq27","volume":"23","author":"Davies","year":"1986","journal-title":"Am. J. Med. Genet."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1126\/science.1245831","article-title":"Promoter-Bound Trinucleotide Repeat mRNA Drives Epigenetic Silencing in Fragile X Syndrome","volume":"343","author":"Colak","year":"2014","journal-title":"Science"},{"key":"ref_5","unstructured":"(2022, June 08). 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Genet."}],"container-title":["Cells"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4409\/11\/12\/1937\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T23:32:48Z","timestamp":1760139168000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4409\/11\/12\/1937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,16]]},"references-count":17,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,6]]}},"alternative-id":["cells11121937"],"URL":"https:\/\/doi.org\/10.3390\/cells11121937","relation":{},"ISSN":["2073-4409"],"issn-type":[{"type":"electronic","value":"2073-4409"}],"subject":[],"published":{"date-parts":[[2022,6,16]]}}}