{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T09:12:08Z","timestamp":1790759528488,"version":"4.1.0"},"reference-count":104,"publisher":"MDPI AG","issue":"14","license":[{"start":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T00:00:00Z","timestamp":1658102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the National Institutes of Health","award":["HL116273-07"],"award-info":[{"award-number":["HL116273-07"]}]},{"name":"the National Institutes of Health","award":["K08HL141590"],"award-info":[{"award-number":["K08HL141590"]}]},{"name":"the Jack and Gitta Nagel and Family Endowed Cardiac Surgery Fellowship","award":["HL116273-07"],"award-info":[{"award-number":["HL116273-07"]}]},{"name":"the Jack and Gitta Nagel and Family Endowed Cardiac Surgery Fellowship","award":["K08HL141590"],"award-info":[{"award-number":["K08HL141590"]}]},{"name":"National Institutes of Health","award":["HL116273-07"],"award-info":[{"award-number":["HL116273-07"]}]},{"name":"National Institutes of Health","award":["K08HL141590"],"award-info":[{"award-number":["K08HL141590"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cells"],"abstract":"<jats:p>Cardiovascular disease is a leading cause of death worldwide. The underlying mechanisms of most cardiovascular disorders involve innate and adaptive immune responses, and extracellular vesicles are implicated in both. In this review, we describe the mechanistic role of extracellular vesicles at the intersection of inflammatory processes and cardiovascular disease. Our discussion focuses on atherosclerosis, myocardial ischemia and ischemic heart disease, heart failure, aortic aneurysms, and valvular pathology.<\/jats:p>","DOI":"10.3390\/cells11142229","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T11:32:23Z","timestamp":1658143943000},"page":"2229","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Extracellular Vesicles, Inflammation, and Cardiovascular Disease"],"prefix":"10.3390","volume":"11","author":[{"given":"Akbarshakh","family":"Akhmerov","sequence":"first","affiliation":[{"name":"Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4790-0730","authenticated-orcid":false,"given":"Tanyalak","family":"Parimon","sequence":"additional","affiliation":[{"name":"Women\u2019s Guild Lung Institute, Pulmonary and Critical Care Division, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,7,18]]},"reference":[{"key":"ref_1","unstructured":"WHO (2022, May 18). 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