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Sci."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s40263-019-00630-6","article-title":"Pathophysiological Mechanisms in Migraine and the Identification of New Therapeutic Targets","volume":"33","author":"Haanes","year":"2019","journal-title":"CNS Drugs"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1055\/s-0039-1700525","article-title":"Migraine Aura: Pathophysiology, Mimics, and Treatment Options","volume":"39","author":"Fraser","year":"2019","journal-title":"Semin. Neurol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s10194-019-1043-7","article-title":"Animal models of migraine and experimental techniques used to examine trigeminal sensory processing","volume":"20","author":"Harriott","year":"2019","journal-title":"J. Headache Pain"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s10072-020-04808-5","article-title":"Migraine neuroscience: From experimental models to target therapy","volume":"41","author":"Greco","year":"2020","journal-title":"Neurol. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Tardiolo, G., Bramanti, P., and Mazzon, E. (2019). Migraine: Experimental Models and Novel Therapeutic Approaches. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20122932"},{"key":"ref_17","first-page":"e1166","article-title":"Correlation of neurochemical and imaging markers in migraine: PACAP38 and DTI measures","volume":"91","author":"Tuka","year":"2018","journal-title":"Neurology"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Szab\u00f3, N., Farag\u00f3, P., Kir\u00e1ly, A., Ver\u00e9b, D., Csete, G., T\u00f3th, E., Kocsis, K., Kincses, B., Tuka, B., and P\u00e1rdutz, \u00c1. (2018). Evidence for plastic processes in migraine with aura: A diffusion weighted MRI study. Front. Neuroanat., 11.","DOI":"10.3389\/fnana.2017.00138"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1177\/03331024221111529","article-title":"Personal view: Modelling pain mechanisms of migraine without aura","volume":"42","author":"Olesen","year":"2022","journal-title":"Cephalalgia"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/head.13585","article-title":"Emerging Treatment Targets for Migraine and Other Headaches","volume":"59","author":"Bertels","year":"2019","journal-title":"Headache"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41582-019-0216-y","article-title":"Does inflammation have a role in migraine?","volume":"15","author":"Edvinsson","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s10194-019-0963-6","article-title":"Behavioral and cognitive animal models in headache research","volume":"20","author":"Vuralli","year":"2019","journal-title":"J. Headache Pain"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s11064-021-03335-9","article-title":"Brain Energy Deficit as a Source of Oxidative Stress in Migraine: A Molecular Basis for Migraine Susceptibility","volume":"46","author":"Borkum","year":"2021","journal-title":"Neurochem. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1186\/s10194-019-1066-0","article-title":"Mechanisms of migraine as a chronic evolutive condition","volume":"20","author":"Andreou","year":"2019","journal-title":"J. Headache Pain"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"eabj7360","DOI":"10.1126\/scitranslmed.abj7360","article-title":"Brain circuits for pain and its treatment","volume":"13","author":"Chen","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Vigan\u00f2, A., Toscano, M., Puledda, F., and Di Piero, V. (2019). Treating chronic migraine with neuromodulation: The role of neurophysiological abnormalities and maladaptive plasticity. Front. Pharmacol., 10.","DOI":"10.3389\/fphar.2019.00032"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1177\/0333102420974359","article-title":"How does the brain change in chronic migraine? Developing disease biomarkers","volume":"41","author":"Coppola","year":"2021","journal-title":"Cephalalgia"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1097\/j.pain.0000000000001770","article-title":"Temporal instability of salience network activity in migraine with aura","volume":"161","author":"Tuka","year":"2020","journal-title":"Pain"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Battaglia, S., Avenanti, A., V\u00e9csei, L., and Tanaka, M. (2024). Neural Correlates and Molecular Mechanisms of Memory and Learning. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25052724"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1744806918767697","DOI":"10.1177\/1744806918767697","article-title":"Chronic migraine: A process of dysmodulation and sensitization","volume":"14","author":"Su","year":"2018","journal-title":"Mol. 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Med."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Tanaka, M., Battaglia, S., Gim\u00e9nez-Llort, L., Chen, C., Hepsomali, P., Avenanti, A., and V\u00e9csei, L. (2024). Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry. Cells, 13.","DOI":"10.20944\/preprints202404.1130.v1"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Battaglia, S., Schmidt, A., Hassel, S., and Tanaka, M. (2023). Case reports in neuroimaging and stimulation. Front. Psychiatry, 14.","DOI":"10.3389\/fpsyt.2023.1264669"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Tortora, F., Hadipour, A.L., Battaglia, S., Falzone, A., Avenanti, A., and Vicario, C.M. (2023). The role of serotonin in fear learning and memory: A systematic review of human studies. Brain Sci., 13.","DOI":"10.3390\/brainsci13081197"},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Battaglia, S., Di Fazio, C., Mazz\u00e0, M., Tamietto, M., and Avenanti, A. (2024). Targeting Human Glucocorticoid Receptors in Fear Learning: A Multiscale Integrated Approach to Study Functional Connectivity. Int. J. Mol. Sci., 25.","DOI":"10.3390\/ijms25020864"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1080\/14728222.2020.1724285","article-title":"Calcitonin gene-related peptide (CGRP): Role in migraine pathophysiology and therapeutic targeting","volume":"24","author":"Wattiez","year":"2020","journal-title":"Expert. Opin. Ther. Targets"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1152\/physrev.00059.2021","article-title":"CGRP physiology, pharmacology, and therapeutic targets: Migraine and beyond","volume":"103","author":"Russo","year":"2023","journal-title":"Physiol. Rev."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1177\/0333102417736900","article-title":"Recognizing the role of CGRP and CGRP receptors in migraine and its treatment","volume":"39","author":"Edvinsson","year":"2019","journal-title":"Cephalalgia"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Kamm, K. (2022). CGRP and Migraine: What Have We Learned From Measuring CGRP in Migraine Patients So Far?. Front. Neurol., 13.","DOI":"10.3389\/fneur.2022.930383"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/head.13300","article-title":"A Phase-by-Phase Review of Migraine Pathophysiology","volume":"58","author":"Dodick","year":"2018","journal-title":"Headache"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Vincent, M., Viktrup, L., Nicholson, R.A., Ossipov, M.H., and Vargas, B.B. (2022). The not so hidden impact of interictal burden in migraine: A narrative review. Front. Neurol., 13.","DOI":"10.3389\/fneur.2022.1032103"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1080\/14737175.2022.2091435","article-title":"A systematic review with expert opinion on the role of gepants for the preventive and abortive treatment of migraine","volume":"22","author":"Argyriou","year":"2022","journal-title":"Expert. Rev. Neurother."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1080\/14740338.2020.1811229","article-title":"CGRP inhibitors for migraine prophylaxis: A safety review","volume":"19","author":"MaassenVanDenBrink","year":"2020","journal-title":"Expert. Opin. Drug Saf."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/nrneurol.2010.127","article-title":"CGRP and its receptors provide new insights into migraine pathophysiology","volume":"6","author":"Ho","year":"2010","journal-title":"Nat. Rev. Neurol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Carmine Belin, A., Ran, C., and Edvinsson, L. (2020). Calcitonin gene-related peptide (CGRP) and cluster headache. Brain Sci., 10.","DOI":"10.3390\/brainsci10010030"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/bcp.12686","article-title":"CGRP as a neuropeptide in migraine: Lessons from mice","volume":"80","author":"Russo","year":"2015","journal-title":"Br. J. Clin. Pharmacol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s10194-020-01189-0","article-title":"Plasma levels of CGRP and expression of specific microRNAs in blood cells of episodic and chronic migraine subjects: Towards the identification of a panel of peripheral biomarkers of migraine?","volume":"21","author":"Greco","year":"2020","journal-title":"J. Headache Pain"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s10194-017-0807-1","article-title":"Blocking CGRP in migraine patients\u2014A review of pros and cons","volume":"18","author":"Deen","year":"2017","journal-title":"J. Headache Pain"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/head.13081","article-title":"T he T rigeminovascular P athway: R ole of CGRP and CGRP R eceptors in M igraine","volume":"57","author":"Edvinsson","year":"2017","journal-title":"Headache J. Head. Face Pain"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1440-1681.1996.tb02760.x","article-title":"Recent insights into the regulation of cerebral circulation","volume":"23","author":"Brian","year":"1996","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Kee, Z., Kodji, X., and Brain, S.D. (2018). The role of calcitonin gene related peptide (CGRP) in neurogenic vasodilation and its cardioprotective effects. Front. Physiol., 9.","DOI":"10.3389\/fphys.2018.01249"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0196-9781(01)00408-9","article-title":"Neuronal messengers in the human cerebral circulation","volume":"22","author":"Gulbenkian","year":"2001","journal-title":"Peptides"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"H608","DOI":"10.1152\/ajpheart.01290.2004","article-title":"Remote arteriolar dilations caused by methacholine: A role for CGRP sensory nerves?","volume":"289","author":"Thengchaisri","year":"2005","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ejphar.2019.01.007","article-title":"Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage: Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity","volume":"846","author":"Johansson","year":"2019","journal-title":"Eur. J. Pharmacol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/sj.bjp.0703685","article-title":"Mechanisms of the cutaneous vasodilator response to local external pressure application in rats: Involvement of CGRP, neurokinins, prostaglandins and NO","volume":"131","author":"Fromy","year":"2000","journal-title":"Br. J. Pharmacol."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1046\/j.1468-2982.2002.00378.x","article-title":"An immunocytochemical investigation of human trigeminal nucleus caudalis: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres","volume":"22","author":"Smith","year":"2002","journal-title":"Cephalalgia"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"17448069211059400","DOI":"10.1177\/17448069211059400","article-title":"Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain","volume":"17","author":"Edvinsson","year":"2021","journal-title":"Mol. Pain"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s00702-020-02161-7","article-title":"Cross-talk signaling in the trigeminal ganglion: Role of neuropeptides and other mediators","volume":"127","author":"Messlinger","year":"2020","journal-title":"J. Neural Transm."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s10194-024-01769-4","article-title":"Untangling the mess of CGRP levels as a migraine biomarker: An in-depth literature review and analysis of our experimental experience","volume":"25","author":"Pascual","year":"2024","journal-title":"J. Headache Pain"},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Benedicter, N., Vogler, B., Kuhn, A., Schramm, J., Mackenzie, K.D., Stratton, J., Dux, M., and Messlinger, K. (2024). Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception\u2014Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab. Cells, 13.","DOI":"10.3390\/cells13070572"},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Greco, R., Demartini, C., Francavilla, M., Zanaboni, A.M., and Tassorelli, C. (2022). Antagonism of CGRP receptor: Central and peripheral mechanisms and mediators in an animal model of chronic migraine. Cells, 11.","DOI":"10.3390\/cells11193092"},{"key":"ref_64","doi-asserted-by":"crossref","unstructured":"Dux, M., Vogler, B., Kuhn, A., Mackenzie, K.D., Stratton, J., and Messlinger, K. (2022). The anti-CGRP antibody fremanezumab lowers CGRP release from rat dura mater and meningeal blood flow. Cells, 11.","DOI":"10.3390\/cells11111768"},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Pavelic, A.R., W\u00f6ber, C., Riederer, F., and Zebenholzer, K. (2022). Monoclonal antibodies against calcitonin gene-related peptide for migraine prophylaxis: A systematic review of real-world data. Cells, 12.","DOI":"10.20944\/preprints202211.0177.v1"},{"key":"ref_66","doi-asserted-by":"crossref","unstructured":"Tanaka, M., Szab\u00f3, \u00c1., K\u00f6rt\u00e9si, T., Szok, D., Tajti, J., and V\u00e9csei, L. (2023). From CGRP to PACAP, VIP, and Beyond: Unraveling the Next Chapters in Migraine Treatment. Cells, 12.","DOI":"10.20944\/preprints202309.0459.v2"},{"key":"ref_67","doi-asserted-by":"crossref","unstructured":"Gecse, K., \u00c9des, A.E., Nagy, T., Demeter, A.K., Vir\u00e1g, D., Kir\u00e1ly, M., Dalmadi Kiss, B., Lud\u00e1nyi, K., K\u00f6rnyei, Z., and Denes, A. (2022). Citalopram Neuroendocrine Challenge Shows Altered Tryptophan and Kynurenine Metabolism in Migraine. Cells, 11.","DOI":"10.3390\/cells11142258"},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"K\u00f6rt\u00e9si, T., Spekker, E., and V\u00e9csei, L. (2022). Exploring the tryptophan metabolic pathways in migraine-related mechanisms. 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Pineal Res."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"665","DOI":"10.2174\/1570159X14666151208113006","article-title":"Stress, the autonomic nervous system, and the immune-kynurenine pathway in the etiology of depression","volume":"14","author":"Won","year":"2016","journal-title":"Curr. Neuropharmacol."},{"key":"ref_78","doi-asserted-by":"crossref","unstructured":"Staats Pires, A., Tan, V.X., Heng, B., Guillemin, G.J., and Latini, A. (2020). Kynurenine and tetrahydrobiopterin pathways crosstalk in pain hypersensitivity. Front. Neurosci., 14.","DOI":"10.3389\/fnins.2020.00620"},{"key":"ref_79","first-page":"161","article-title":"Role of tryptophan in health and disease: Systematic review of the anti-oxidant, anti-inflammation, and nutritional aspects of tryptophan and its metabolites","volume":"11","author":"Singh","year":"2019","journal-title":"World Heart J."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.2741\/4363","article-title":"Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation","volume":"20","author":"Wang","year":"2015","journal-title":"Front. Biosci. (Landmark Ed.)"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s10194-021-01239-1","article-title":"Clinical relevance of depressed kynurenine pathway in episodic migraine patients: Potential prognostic markers in the peripheral plasma during the interictal period","volume":"22","author":"Tuka","year":"2021","journal-title":"J. Headache Pain"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1177\/0333102417703762","article-title":"Macro-and microstructural alterations of the subcortical structures in episodic cluster headache","volume":"38","author":"Tajti","year":"2018","journal-title":"Cephalalgia"},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3988\/jcn.2021.17.2.164","article-title":"The role of endothelial dysfunction in the pathophysiology and cerebrovascular effects of migraine: A narrative review","volume":"17","author":"Paolucci","year":"2021","journal-title":"J. Clin. Neurol."},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Fila, M., Chojnacki, J., Pawlowska, E., Szczepanska, J., Chojnacki, C., and Blasiak, J. (2021). Kynurenine pathway of tryptophan metabolism in migraine and functional gastrointestinal disorders. Int. J. Mol. Sci., 22.","DOI":"10.3390\/ijms221810134"},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Jovanovic, F., Candido, K.D., and Knezevic, N.N. (2020). The role of the kynurenine signaling pathway in different chronic pain conditions and potential use of therapeutic agents. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21176045"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Fila, M., Chojnacki, C., Chojnacki, J., and Blasiak, J. (2023). The kynurenine pathway of tryptophan metabolism in abdominal migraine in children\u2013A therapeutic potential?. Eur. J. Paediatr. Neurol.","DOI":"10.20944\/preprints202308.0760.v1"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s10194-023-01570-9","article-title":"Cluster headache and kynurenines","volume":"24","author":"Tuka","year":"2023","journal-title":"J. Headache Pain"},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Tajti, J., Szok, D., Cs\u00e1ti, A., Szab\u00f3, \u00c1., Tanaka, M., and V\u00e9csei, L. (2023). Exploring novel therapeutic targets in the common pathogenic factors in migraine and neuropathic pain. Int. J. Mol. Sci., 24.","DOI":"10.20944\/preprints202301.0034.v1"},{"key":"ref_89","doi-asserted-by":"crossref","unstructured":"Martos, D., L\u0151rinczi, B., Szatm\u00e1ri, I., V\u00e9csei, L., and Tanaka, M. (2024). The Impact of C-3 Side Chain Modifications on Kynurenic Acid: A Behavioral Analysis of Its Analogs in the Motor Domain. Int. J. Mol. Sci., 25.","DOI":"10.20944\/preprints202402.1164.v1"},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"J\u00e1szber\u00e9nyi, M., Thurz\u00f3, B., Bagosi, Z., V\u00e9csei, L., and Tanaka, M. (2024). The Orexin\/Hypocretin System, the Peptidergic Regulator of Vigilance, Orchestrates Adaptation to Stress. Biomedicines, 12.","DOI":"10.3390\/biomedicines12020448"},{"key":"ref_91","doi-asserted-by":"crossref","unstructured":"Tanaka, M., Boh\u00e1r, Z., and V\u00e9csei, L. (2020). Are kynurenines accomplices or principal villains in dementia? Maintenance of kynurenine metabolism. Molecules, 25.","DOI":"10.3390\/molecules25030564"},{"key":"ref_92","doi-asserted-by":"crossref","unstructured":"Tanaka, M., and V\u00e9csei, L. (2024). A Decade of Dedication: Pioneering Perspectives on Neurological Diseases and Mental Illnesses. Biomedicines, 12.","DOI":"10.3390\/biomedicines12051083"},{"key":"ref_93","doi-asserted-by":"crossref","unstructured":"Tanaka, M., and V\u00e9csei, L. (2024). From Lab to Life: Exploring Cutting-Edge Models for Neurological and Psychiatric Disorders. Biomedicines, 12.","DOI":"10.20944\/preprints202403.0259.v1"},{"key":"ref_94","doi-asserted-by":"crossref","unstructured":"Tanaka, M., Szab\u00f3, \u00c1., V\u00e9csei, L., and Gim\u00e9nez-Llort, L. (2023). Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models. Int. J. Mol. Sci., 24.","DOI":"10.20944\/preprints202310.0800.v1"},{"key":"ref_95","doi-asserted-by":"crossref","unstructured":"Spekker, E., Tanaka, M., Szab\u00f3, \u00c1., and V\u00e9csei, L. (2021). Neurogenic inflammation: The participant in migraine and recent advancements in translational research. Biomedicines, 10.","DOI":"10.3390\/biomedicines10010076"},{"key":"ref_96","doi-asserted-by":"crossref","unstructured":"Khan, J., Al Asoom, L.I., Al Sunni, A., Rafique, N., Latif, R., Al Saif, S., Almandil, N.B., Almohazey, D., AbdulAzeez, S., and Borgio, J.F. (2021). Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine. Biomed. Pharmacother., 139.","DOI":"10.1016\/j.biopha.2021.111557"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/14728222.2020.1728255","article-title":"Migraine pathways and the identification of novel therapeutic targets","volume":"24","author":"Rainero","year":"2020","journal-title":"Expert. Opin. Ther. Targets"},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.tips.2021.01.002","article-title":"Identifying new antimigraine targets: Lessons from molecular biology","volume":"42","author":"Edvinsson","year":"2021","journal-title":"Trends Pharmacol. Sci."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/14737175.2020.1729130","article-title":"Metabolic treatments of migraine","volume":"20","author":"Lisicki","year":"2020","journal-title":"Expert. Rev. Neurother."},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"136380","DOI":"10.1016\/j.neulet.2021.136380","article-title":"The role of TRP ion channels in migraine and headache","volume":"768","author":"Iannone","year":"2022","journal-title":"Neurosci. Lett."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1186\/s10194-022-01412-0","article-title":"Involvement of adenosine signaling pathway in migraine pathophysiology: A systematic review of preclinical studies","volume":"23","author":"Thuraiaiyah","year":"2022","journal-title":"J. Headache Pain"},{"key":"ref_102","doi-asserted-by":"crossref","unstructured":"Nisar, A., Ahmed, Z., and Yuan, H. (2023). Novel therapeutic targets for migraine. Biomedicines, 11.","DOI":"10.3390\/biomedicines11020569"},{"key":"ref_103","first-page":"S16","article-title":"Neurogenic inflammation in the pathophysiology and treatment of migraine","volume":"43","author":"Moskowitz","year":"1993","journal-title":"Neurol. Minneap."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Biscetti, L., Cresta, E., Cupini, L.M., Calabresi, P., and Sarchielli, P. (2023). The putative role of neuroinflammation in the complex pathophysiology of migraine: From bench to bedside. Neurobiol. Dis.","DOI":"10.1016\/j.nbd.2023.106072"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s10194-022-01478-w","article-title":"Disease-and headache-specific microRNA signatures and their predicted mRNA targets in peripheral blood mononuclear cells in migraineurs: Role of inflammatory signalling and oxidative stress","volume":"23","author":"Benczik","year":"2022","journal-title":"J. Headache Pain"},{"key":"ref_106","first-page":"1","article-title":"Identification of disease-and headache-specific mediators and pathways in migraine using blood transcriptomic and metabolomic analysis","volume":"22","author":"Kun","year":"2021","journal-title":"J. Headache Pain"},{"key":"ref_107","doi-asserted-by":"crossref","unstructured":"Suzuki, K., Suzuki, S., Shiina, T., Kobayashi, S., and Hirata, K. (2022). Central sensitization in migraine: A narrative review. J. Pain Res., 2673\u20132682.","DOI":"10.2147\/JPR.S329280"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00281-018-0676-y","article-title":"Neurogenic inflammation and its role in migraine","volume":"40","author":"Ramachandran","year":"2018","journal-title":"Semin. Immunopathol."},{"key":"ref_109","doi-asserted-by":"crossref","unstructured":"Mungoven, T.J., Henderson, L.A., and Meylakh, N. (2021). Chronic migraine pathophysiology and treatment: A review of current perspectives. Front. Pain Res., 2.","DOI":"10.3389\/fpain.2021.705276"},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1111\/head.14352","article-title":"Migraine and peripheral pain models show differential alterations in neuronal complexity","volume":"62","author":"Bertels","year":"2022","journal-title":"Headache"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1136\/practneurol-2020-002844","article-title":"Migraine: Beyond pain","volume":"21","author":"Karsan","year":"2021","journal-title":"Pract. Neurol."},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Tuttolomondo, A., and Simonetta, I. (2023). Molecular Research on Migraine: From Pathogenesis to Treatment. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24108681"},{"key":"ref_113","doi-asserted-by":"crossref","unstructured":"Rattanawong, W., Rapoport, A., and Srikiatkhachorn, A. (2022). Neurobiology of migraine progression. Neurobiol. Pain, 12.","DOI":"10.1016\/j.ynpai.2022.100094"},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1177\/1073858413503711","article-title":"Migraine mistakes: Error awareness","volume":"20","author":"Borsook","year":"2014","journal-title":"Neuroscientist"},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1177\/2049463719889380","article-title":"Interrelations between pain, stress and executive functioning","volume":"14","author":"Feller","year":"2020","journal-title":"Br. J. Pain"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/acps.13602","article-title":"Heart's tale of trauma: Fear-conditioned heart rate changes in post-traumatic stress disorder","volume":"148","author":"Battaglia","year":"2023","journal-title":"Acta Psychiatr. Scand."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Di Gregorio, F., Steinhauser, M., Maier, M.E., Thayer, J.F., and Battaglia, S. (2024). Error-related cardiac deceleration: Functional interplay between error-related brain activity and autonomic nervous system in performance monitoring. Neurosci. Biobehav. Rev.","DOI":"10.1016\/j.neubiorev.2024.105542"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41398-024-02737-x","article-title":"Genetic differences associated with dopamine and serotonin release mediate fear-induced bradycardia in the human brain","volume":"14","author":"Battaglia","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11910-015-0547-z","article-title":"CGRP mechanism antagonists and migraine management","volume":"15","author":"Karsan","year":"2015","journal-title":"Curr. Neurol. Neurosci. Rep."},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1038\/s41582-019-0255-4","article-title":"The metabolic face of migraine\u2014From pathophysiology to treatment","volume":"15","author":"Gross","year":"2019","journal-title":"Nat. Rev. Neurol."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1468-2982.2005.01082.x","article-title":"Experimental migraine models and their relevance in migraine therapy","volume":"26","author":"Arulmani","year":"2006","journal-title":"Cephalalgia"},{"key":"ref_122","doi-asserted-by":"crossref","unstructured":"Pagotto, G.L.d.O., Santos, L.M.O.d., Osman, N., Lamas, C.B., Laurindo, L.F., Pomini, K.T., Guissoni, L.M., Lima, E.P.d., Goulart, R.d.A., and Catharin, V.M.S. (2024). Ginkgo biloba: A Leaf of Hope in the Fight against Alzheimer\u2019s Dementia: Clinical Trial Systematic Review. Antioxidants, 13.","DOI":"10.20944\/preprints202404.0852.v1"},{"key":"ref_123","doi-asserted-by":"crossref","unstructured":"Valotto Neto, L.J., Reverete de Araujo, M., Moretti Junior, R.C., Mendes Machado, N., Joshi, R.K., dos Santos Buglio, D., Barbalho Lamas, C., Direito, R., Fornari Laurindo, L., and Tanaka, M. (2024). Investigating the Neuroprotective and Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review Focused on Inflammation, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis. Antioxidants, 13.","DOI":"10.3390\/antiox13040393"},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"109670","DOI":"10.1016\/j.jnutbio.2024.109670","article-title":"Pomegranate (Punica granatum L.) phytochemicals target the components of metabolic syndrome","volume":"131","author":"Laurindo","year":"2024","journal-title":"J. Nutr. Biochem."},{"key":"ref_125","doi-asserted-by":"crossref","unstructured":"Direito, R., Barbalho, S.M., Sepodes, B., and Figueira, M.E. (2024). Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention. Pharmaceutics, 16.","DOI":"10.20944\/preprints202402.0641.v1"},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"100771","DOI":"10.1016\/j.hermed.2023.100771","article-title":"The Effects of Curcumin on Neurodegenerative Diseases: A Systematic Review","volume":"42","author":"Audi","year":"2023","journal-title":"J. Herb. Med."},{"key":"ref_127","doi-asserted-by":"crossref","unstructured":"Pasierski, M., and Szulczyk, B. (2022). Beneficial effects of capsaicin in disorders of the central nervous system. Molecules, 27.","DOI":"10.3390\/molecules27082484"},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1002\/ptr.7339","article-title":"Role of herbal medicine for prevention and treatment of migraine","volume":"36","author":"Chen","year":"2022","journal-title":"Phytother. Res."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.2174\/0929867326666190125155947","article-title":"Natural products and their (semi-) synthetic forms in the treatment of migraine: History and current status","volume":"27","author":"Tauchen","year":"2020","journal-title":"Curr. Med. Chem."},{"key":"ref_130","doi-asserted-by":"crossref","unstructured":"Wei, T.-H., and Hsieh, C.-L. (2023). Headaches, migraine, and herbal medicine. Treatments, Nutraceuticals, Supplements, and Herbal Medicine in Neurological Disorders, Elsevier.","DOI":"10.1016\/B978-0-323-90052-2.00006-8"},{"key":"ref_131","doi-asserted-by":"crossref","unstructured":"Minniti, G., Laurindo, L.F., Machado, N.M., Duarte, L.G., Guiguer, E.L., Araujo, A.C., Dias, J.A., Lamas, C.B., Nunes, Y.C., and Bechara, M.D. (2023). Mangifera indica L., By-Products, and Mangiferin on Cardio-Metabolic and Other Health Conditions: A Systematic Review. Life, 13.","DOI":"10.3390\/life13122270"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1089\/act.2017.29131.eya","article-title":"Herbal medicine and migraine","volume":"23","author":"Yarnell","year":"2017","journal-title":"Altern. Complement. Ther."},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"4333","DOI":"10.1080\/87559129.2021.2023819","article-title":"Psidium guajava L.: A systematic review of the multifaceted health benefits and economic importance","volume":"39","author":"Takeda","year":"2023","journal-title":"Food Rev. Int."},{"key":"ref_134","doi-asserted-by":"crossref","unstructured":"Laurindo, L.F., Barbalho, S.M., Ara\u00fajo, A.C., Guiguer, E.L., Mondal, A., Bachtel, G., and Bishayee, A. (2023). A\u00e7a\u00ed (Euterpe oleracea Mart.) in health and disease: A critical review. Nutrients, 15.","DOI":"10.3390\/nu15040989"},{"key":"ref_135","doi-asserted-by":"crossref","unstructured":"Nishikito, D.F., Borges, A.C.A., Laurindo, L.F., Otoboni, A.M.B., Direito, R., Goulart, R.d.A., Nicolau, C.C., Fiorini, A.M., Sinatora, R.V., and Barbalho, S.M. (2023). Anti-inflammatory, antioxidant, and other health effects of dragon fruit and potential delivery systems for its bioactive compounds. Pharmaceutics, 15.","DOI":"10.3390\/pharmaceutics15010159"},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1089\/jmf.2021.0084","article-title":"The role of resveratrol in mild cognitive impairment and Alzheimer's disease: A systematic review","volume":"25","author":"Buglio","year":"2022","journal-title":"J. Med. Food"},{"key":"ref_137","doi-asserted-by":"crossref","unstructured":"Zhong, J., Lan, W., Feng, Y., Yu, L., Xiao, R., Shen, Y., Zou, Z., and Hou, X. (2022). Efficacy of repetitive transcranial magnetic stimulation on chronic migraine: A meta-analysis. Front. Neurol., 13.","DOI":"10.3389\/fneur.2022.1050090"},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/nyas.15145","article-title":"The role of pre-supplementary motor cortex in action control with emotional stimuli: A repetitive transcranial magnetic stimulation study","volume":"1536","author":"Battaglia","year":"2024","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ref_139","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1097\/PHM.0000000000001953","article-title":"Effectiveness of high-frequency repetitive transcranial magnetic stimulation in migraine: A systematic review and meta-analysis","volume":"101","author":"Saltychev","year":"2022","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"ref_140","doi-asserted-by":"crossref","first-page":"104548","DOI":"10.1016\/j.brat.2024.104548","article-title":"\u2018Nip it in the bud\u2019: Low-frequency rTMS of the prefrontal cortex disrupts threat memory consolidation in humans","volume":"178","author":"Battaglia","year":"2024","journal-title":"Behav. Res. Ther."},{"key":"ref_141","doi-asserted-by":"crossref","first-page":"113790","DOI":"10.1016\/j.psychres.2021.113790","article-title":"Optimized repetitive transcranial magnetic stimulation techniques for the treatment of major depression: A proof of concept study","volume":"298","author":"Miron","year":"2021","journal-title":"Psychiatry Res."},{"key":"ref_142","doi-asserted-by":"crossref","unstructured":"Zhang, J.-H., Liang, J., and Yang, Z.-W. (2023). Non-invasive brain stimulation for fibromyalgia: Current trends and future perspectives. Front. Neurosci., 17.","DOI":"10.3389\/fnins.2023.1288765"}],"container-title":["Cells"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2073-4409\/13\/13\/1098\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:04:08Z","timestamp":1760108648000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2073-4409\/13\/13\/1098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,25]]},"references-count":142,"journal-issue":{"issue":"13","published-online":{"date-parts":[[2024,7]]}},"alternative-id":["cells13131098"],"URL":"https:\/\/doi.org\/10.3390\/cells13131098","relation":{},"ISSN":["2073-4409"],"issn-type":[{"value":"2073-4409","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,25]]}}}