{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:32:47Z","timestamp":1791228767650,"version":"4.1.0"},"reference-count":125,"publisher":"MDPI AG","issue":"17","license":[{"start":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T00:00:00Z","timestamp":1724371200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Agence Nationale pour la Recherche (ANR)","award":["CILIAINTHEBRAIN"],"award-info":[{"award-number":["CILIAINTHEBRAIN"]}]},{"name":"Agence Nationale pour la Recherche (ANR)","award":["EQU201903007943"],"award-info":[{"award-number":["EQU201903007943"]}]},{"name":"Agence Nationale pour la Recherche (ANR)","award":["DEQ20140329544"],"award-info":[{"award-number":["DEQ20140329544"]}]},{"name":"Fondation pour la Recherche M\u00e9dicale (FRM)","award":["CILIAINTHEBRAIN"],"award-info":[{"award-number":["CILIAINTHEBRAIN"]}]},{"name":"Fondation pour la Recherche M\u00e9dicale (FRM)","award":["EQU201903007943"],"award-info":[{"award-number":["EQU201903007943"]}]},{"name":"Fondation pour la Recherche M\u00e9dicale (FRM)","award":["DEQ20140329544"],"award-info":[{"award-number":["DEQ20140329544"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cells"],"abstract":"<jats:p>Ciliated epithelia are widespread in animals and play crucial roles in many developmental and physiological processes. Epithelia composed of multi-ciliated cells allow for directional fluid flow in the trachea, oviduct and brain cavities. Monociliated epithelia play crucial roles in vertebrate embryos, from the establishment of left\u2013right asymmetry to the control of axis curvature via cerebrospinal flow motility in zebrafish. Cilia also have a central role in the motility and feeding of free-swimming larvae in a variety of marine organisms. These diverse functions rely on the coordinated orientation (rotational polarity) and asymmetric localization (translational polarity) of cilia and of their centriole-derived basal bodies across the epithelium, both being forms of planar cell polarity (PCP). Here, we review our current knowledge on the mechanisms of the translational polarity of basal bodies in vertebrate monociliated epithelia from the molecule to the whole organism. We highlight the importance of live imaging for understanding the dynamics of centriole polarization. We review the roles of core PCP pathways and of apicobasal polarity proteins, such as Par3, whose central function in this process has been recently uncovered. Finally, we emphasize the importance of the coordination between polarity proteins, the cytoskeleton and the basal body itself in this highly dynamic process.<\/jats:p>","DOI":"10.3390\/cells13171403","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T12:38:43Z","timestamp":1724416723000},"page":"1403","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Centriole Translational Planar Polarity in Monociliated Epithelia"],"prefix":"10.3390","volume":"13","author":[{"given":"Antoine","family":"Donati","sequence":"first","affiliation":[{"name":"Developmental Biology Unit, UMR7622, Institut de Biologie Paris Seine (IBPS), Sorbonne Universit\u00e9, CNRS, INSERM U1156, 75005 Paris, France"},{"name":"Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-4735","authenticated-orcid":false,"given":"Sylvie","family":"Schneider-Maunoury","sequence":"additional","affiliation":[{"name":"Developmental Biology Unit, UMR7622, Institut de Biologie Paris Seine (IBPS), Sorbonne Universit\u00e9, CNRS, INSERM U1156, 75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7983-4953","authenticated-orcid":false,"given":"Christine","family":"Vesque","sequence":"additional","affiliation":[{"name":"Developmental Biology Unit, UMR7622, Institut de Biologie Paris Seine (IBPS), Sorbonne Universit\u00e9, CNRS, INSERM U1156, 75005 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.ceb.2010.07.011","article-title":"Planar Cell Polarity Signaling, Cilia and Polarized Ciliary Beating","volume":"22","author":"Wallingford","year":"2010","journal-title":"Curr. 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