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Over the last 20 years, researchers have investigated mesenchymal stem cell infusion and the transplantation of stem cell-derived \u03b2 cells and islet tissues. This review aims to comprehensively discuss the latest advances in the field of stem cell use in diabetes, including clinical studies and preclinical experiments aiming at improving the efficacy and safety of stem cell use.<\/jats:p>","DOI":"10.3390\/cells15100907","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T08:06:26Z","timestamp":1779696386000},"page":"907","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["What Is the Current State of Stem Cell Therapy in Diabetes?"],"prefix":"10.3390","volume":"15","author":[{"given":"Estera","family":"Bakinowska","sequence":"first","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech Jerzy","family":"Biniek","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8227-6753","authenticated-orcid":false,"given":"Kajetan","family":"Kie\u0142bowski","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0384-1692","authenticated-orcid":false,"given":"Kamil","family":"Dyrka","sequence":"additional","affiliation":[{"name":"Doctoral School, Poznan University of Medical Sciences, 60-812 Poznan, Poland"},{"name":"Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, University of Medical Sciences, 60-572 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9182-9875","authenticated-orcid":false,"given":"Konrad","family":"Szewczyk","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Osta\u0142owska","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4234-1772","authenticated-orcid":false,"given":"Zuzanna","family":"Leciej","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6557-1208","authenticated-orcid":false,"given":"Andrzej","family":"Pawlik","sequence":"additional","affiliation":[{"name":"Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Zhang, J., Xiao, Y., Hu, J., Liu, S., Zhou, Z., and Xie, L. 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