{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T18:08:40Z","timestamp":1768586920170,"version":"3.49.0"},"reference-count":36,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: Gestational SARS-CoV-2 infection can impact maternal and neonatal health. The virus has also been reported to cause newborn sensorineural hearing loss, but its consequences for the auditory system are not fully understood. Objective: The aim of this study was to evaluate the impact of maternal SARS-CoV-2 infection during pregnancy on newborn\u2019 hearing function during the first year of life. Methods: An observational study was conducted from 1 November 2020 to 30 November 2021 at University Modena Hospital. All newborns whose mother had been infected by SARS-CoV-2 during pregnancy were enrolled and underwent audiological evaluation at birth and at 1 year of age. Results: A total of 119 neonates were born from mothers infected by SARS-CoV-2 during pregnancy. At birth, five newborns (4.2%) presented an increased threshold of ABR (Auditory Brainstem Evoked Response), but the results were confirmed only in 1.6% of cases, when repeated 1 month later, while the ABR thresholds in all other children returned to normal limits. At the 1-year follow-up, no cases of moderate or severe hearing loss were observed, while concomitant disorders of the middle ear were frequently observed. Conclusions: Maternal SARS-CoV-2 infection, regardless of the trimester in which it was contracted, appears not to induce moderate or severe hearing loss in infants. It is important to clarify the possible effect of the virus on late-onset hearing loss and future research is needed.<\/jats:p>","DOI":"10.3390\/children10020194","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T02:35:55Z","timestamp":1674182155000},"page":"194","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Monitoring of Auditory Function in Newborns of Women Infected by SARS-CoV-2 during Pregnancy"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0688-5770","authenticated-orcid":false,"given":"Enrico","family":"Apa","sequence":"first","affiliation":[{"name":"Otorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Teresa","family":"Presutti","sequence":"additional","affiliation":[{"name":"Infectious Disease Unit, Department of Medical and Surgical Sciences, Sant\u2019Orsola-Malpighi Hospital, University of Bologna, 40100 Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Rossi","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Federica","family":"Roversi","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Neri","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Gargano","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Paediatrics, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42121 Reggio Emilia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Bianchin","sequence":"additional","affiliation":[{"name":"Department of Audiology, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42123 Reggio Emilia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Polizzi","sequence":"additional","affiliation":[{"name":"Department of Audiology, Santa Maria Nuova Hospital, Centre for Clinical and Basic Research (IRCCS), 42123 Reggio Emilia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Caragli","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Monzani","sequence":"additional","affiliation":[{"name":"ENT, Department of Surgical Sciences, Dentistry, Gynaecology and Paediatrics, University of Verona, Borgo Roma Hospital, 37100 Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3534-7499","authenticated-orcid":false,"given":"Alberto","family":"Berardi","sequence":"additional","affiliation":[{"name":"Neonatal Intensive Care Unit, Department of Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5521-4343","authenticated-orcid":false,"given":"Silvia","family":"Palma","sequence":"additional","affiliation":[{"name":"Audiology, Primary Care Department; AUSL of Modena, 41100 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Genovese","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Unit, Department of Medical and Surgical Sciences for Children and Adults, Azienda Ospedaliero-Universitaria of Modena, 41125 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/s41591-021-01397-4","article-title":"SARS-CoV-2 variants of concern are emerging in India","volume":"27","author":"Singh","year":"2021","journal-title":"Nat. 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