{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T05:11:32Z","timestamp":1784869892433,"version":"3.55.0"},"reference-count":29,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"publisher","award":["484120"],"award-info":[{"award-number":["484120"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Charles University","doi-asserted-by":"publisher","award":["260500"],"award-info":[{"award-number":["260500"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"name":"institutional support programme Cooperation, research area HEAS","award":["484120"],"award-info":[{"award-number":["484120"]}]},{"name":"institutional support programme Cooperation, research area HEAS","award":["260500"],"award-info":[{"award-number":["260500"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Children"],"abstract":"<jats:p>Background: The World Health Organisation defines dual diagnosis as the co-occurrence in the same individual of a psychoactive substance use disorder and another psychiatric disorder. Children and adolescents with dual diagnoses represent a significant public health burden in social and financial terms. Aims: The objective of the present paper is to provide a review of studies dealing with dual diagnoses and their prevalence among children and adolescents whose primary treatment involves psychiatric conditions. Methods: The PRISMA was used to conduct a systematic search. Articles published between January 2010 and May 2022 were searched for analysis. Results: Eight articles were eventually found eligible for the final content analysis. The analysis of the articles identified the prevalence of dual diagnoses among children and adolescents treated primarily for psychiatric conditions, the gender-specific occurrence of dual diagnoses, methods used to diagnose psychiatric and substance use disorders, types of psychiatric diagnoses involved in dual diagnoses, and prevalence differences contingent on the type of service provision as the main thematic areas. The prevalence of dual diagnoses among the target population ranged from 18.3% to 54% (mean 32.7%). Boys were more likely to experience dual diagnoses and affective disorders were the most frequent psychiatric diagnoses. Conclusion: The importance of the issue and the high prevalence of dual diagnoses make it imperative that this type of research is pursued.<\/jats:p>","DOI":"10.3390\/children10020293","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T04:55:12Z","timestamp":1675313712000},"page":"293","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Prevalence of Dual Diagnoses among Children and Adolescents with Mental Health Conditions"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8230-8580","authenticated-orcid":false,"given":"Jand\u00e1\u010d","family":"Tom\u00e1\u0161","sequence":"first","affiliation":[{"name":"First Faculty of Medicine, Department of Addictology, Charles University, 12108 Prague, Czech Republic"},{"name":"Department of Addictology, General University Hospital in Prague, 12800 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0160\u0165astn\u00e1","family":"Lenka","sequence":"additional","affiliation":[{"name":"First Faculty of Medicine, Department of Addictology, Charles University, 12108 Prague, Czech Republic"},{"name":"Department of Addictology, General University Hospital in Prague, 12800 Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"ref_1","unstructured":"EMCDDA (2004). Drugs in Focus, EMCDDAL. [14th ed.]."},{"key":"ref_2","unstructured":"Hughes, L. (2006). Closing the Gap: Dual Diagnosis Framework, DOH\/CSIP."},{"key":"ref_3","unstructured":"Harvey, C., McGill, K., Kinney, C., Harvey, M., Blumberg, E., and Farr, J. (2022). FDDC-NADD Dual Diagnosis Study, Final Research Study Report, Florida Developmental Disabilities Council."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"e145905","DOI":"10.1155\/2015\/145905","article-title":"Substance Use and Dual Diagnosis Disorders: Future Epidemiology, Determinants, and Policies","volume":"2015","author":"Saddichha","year":"2015","journal-title":"BioMed Res. Int."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0740-5472(01)00193-3","article-title":"Dual diagnosis and successful participation of adolescents in substance abuse treatment","volume":"21","author":"Wise","year":"2001","journal-title":"J. Subst. Abus. Treat."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00004583-199701000-00013","article-title":"Is ADHD a risk factor for psychoactive substance use disorders? Findings from a four-year prospective follow-up study","volume":"36","author":"Biederman","year":"1997","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00787-006-0535-6","article-title":"Comorbid psychopathology in adolescents and young adults treated for substance use disorders: A review","volume":"15","author":"Couwenbergh","year":"2006","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1001\/archpedi.152.10.952","article-title":"Substance Abuse in Children: Prediction, Protection, and Prevention","volume":"152","author":"Belcher","year":"1998","journal-title":"Arch. Pediatr. Adolesc. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00004583-200104000-00010","article-title":"Prevalence of Adolescent Substance Use Disorders Across Five Sectors of Care","volume":"40","author":"Aarons","year":"2001","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.jaac.2014.04.018","article-title":"Risk and Protective Factors Associated with Substance Use Disorders in Adolescents with First-Episode Mania","volume":"53","author":"Stephens","year":"2014","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_11","first-page":"69","article-title":"Autism Spectrum Disorder and Co-occurring Substance Use Disorder\u2014A Systematic Review","volume":"10","author":"Arnevik","year":"2016","journal-title":"Subst. Abus. Res. Treat."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/ajad.12808","article-title":"Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults: Dual diagnosis in Mexican adolescents","volume":"27","author":"Corona","year":"2018","journal-title":"Am. J. Addict."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.jaac.2013.07.009","article-title":"Predictors of First-Onset Substance Use Disorders During the Prospective Course of Bipolar Spectrum Disorders in Adolescents","volume":"52","author":"Goldstein","year":"2013","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1080\/17523281.2011.578583","article-title":"Correlates of substance use disorder in bipolar disorder: A systematic review and meta-analysis","volume":"4","author":"Richardson","year":"2011","journal-title":"Ment. Health Subst. Use Dual Diagn."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.addbeh.2012.03.026","article-title":"Longitudinal investigation of the impact of anxiety and mood disorders in adolescence on subsequent substance use disorder onset and vice versa","volume":"37","author":"Bobova","year":"2012","journal-title":"Addict. Behav."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1001\/archpsyc.60.7.709","article-title":"Prior Juvenile Diagnoses in Adults with Mental Disorder: Developmental Follow-Back of a Prospective-Longitudinal Cohort","volume":"60","author":"Caspi","year":"2003","journal-title":"Arch. Gen. Psychiatry"},{"key":"ref_17","first-page":"e15602","article-title":"Substance Use Disorders (SUD) and Suicidal Behaviors in Adolescents: Insights From Cross-Sectional Inpatient Study","volume":"13","author":"Basith","year":"2021","journal-title":"Cureus J. Med. Sci."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Queeneth, U., Bhimanadham, N.N., Mainali, P., Onyeaka, H.K., Pankaj, A., and Patel, R.S. (2019). Heroin Overdose-Related Child and Adolescent Hospitalizations: Insight on Comorbid Psychiatric and Substance Use Disorders. Behav. Sci., 9.","DOI":"10.3390\/bs9070077"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Babor, T.F., Stenius, K., Pates, R., Miovsk\u00fd, M., O\u2019reilly, J., and Candon, P. (2017). Publishing Addiction Science: A Guide for the Perplexed, Ubiquity Press. Available online: http:\/\/www.jstor.org\/stable\/j.ctv3t5qxw.","DOI":"10.5334\/bbd"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Moher, D., Liberati, A., Tetzlaff, J., Altman, D.G., and PRISMA Group (2009). Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Medicine, 6.","DOI":"10.1371\/journal.pmed.1000097"},{"key":"ref_21","unstructured":"Higgins, J.P.T., and Green, S. (2011). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1, The Cochrane Collaboration. Available online: http:\/\/handbook.cochrane.org."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00787-011-0173-5","article-title":"Patterns of substance use in adolescents attending a mental health department","volume":"20","author":"Goti","year":"2011","journal-title":"Eur. Child Adolesc. Psychiatry"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.jsat.2011.09.010","article-title":"Moderators of fluoxetine treatment response for children and adolescents with comorbid depression and substance use disorders","volume":"42","author":"Hirschtritt","year":"2012","journal-title":"J. Subst. Abus. Treat."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Masroor, A., Patel, R.S., Bhimanadham, N.N., Raveendran, S., Ahmad, N., Queeneth, U., Pankaj, A., and Mansuri, Z. (2019). Conduct Disorder-Related Hospitalization and Substance Use Disorders in American Teens. Behav. Sci., 9.","DOI":"10.3390\/bs9070073"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.drugalcdep.2013.01.015","article-title":"Difficulties in emotional regulation and substance use disorders: A controlled family study of bipolar adolescents","volume":"132","author":"Wilens","year":"2013","journal-title":"Drug Alcohol Depend."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.jpsychires.2011.06.012","article-title":"Substance use disorders and comorbid Axis I and II psychiatric disorders among young psychiatric patients: Findings from a large electronic health records database","volume":"45","author":"Wu","year":"2011","journal-title":"J. Psychiatr. Res."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13034-016-0096-5","article-title":"Substance abuse and personality disorder comorbidity in adolescent outpatients: Are girls more severely ill than boys?","volume":"10","author":"Korsgaard","year":"2016","journal-title":"Child Adolesc. Psychiatry Ment. Health"},{"key":"ref_28","first-page":"53","article-title":"A retrospective chart review of the clinical and psychosocial profile of psychotic adolescents with co-morbid substance use disorders presenting to acute adolescent psychiatric services at Tygerberg Hospital","volume":"18","author":"Lachman","year":"2012","journal-title":"South Afr. J. Psychiatry"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1080\/1067828X.2013.768575","article-title":"Mental Health and Substance Use Comorbidity Among Adolescents in Psychiatric Inpatient Hospitals: Prevalence and Covariates","volume":"24","author":"Hollen","year":"2015","journal-title":"J. Child Adolesc. Subst. Abus."}],"container-title":["Children"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2227-9067\/10\/2\/293\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:22:09Z","timestamp":1760120529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2227-9067\/10\/2\/293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,2]]},"references-count":29,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,2]]}},"alternative-id":["children10020293"],"URL":"https:\/\/doi.org\/10.3390\/children10020293","relation":{},"ISSN":["2227-9067"],"issn-type":[{"value":"2227-9067","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,2]]}}}